Results 191 to 200 of about 20,173 (228)
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New England Journal of Medicine, 1971
For almost 100 years Tay-Sachs disease was the only ganglioside storage disease known. A second inborn error of ganglioside metabolism, generalized gangliosidosis, was discovered in 1965.13,35 Three additional ganglioside storage diseases have recently been uncovered,4,3,52,66,74 bringing the total to five.36 Of these, three involve storage of ...
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For almost 100 years Tay-Sachs disease was the only ganglioside storage disease known. A second inborn error of ganglioside metabolism, generalized gangliosidosis, was discovered in 1965.13,35 Three additional ganglioside storage diseases have recently been uncovered,4,3,52,66,74 bringing the total to five.36 Of these, three involve storage of ...
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GANGLIOSIDES IN THE NERVOUS SYSTEM
Neurochemistry International, 1983Gangliosides, sialic acid-containing glycosphingolipids, are embedded in neural plasma membranes to provide cell surface recognition sites with negative charges. Exogenous ligands such as bacterial toxins, hormones, growth factors, antibodies, viruses, and interferons bind to specific gangliosides to induce sequential activations of cellular ...
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2019
Gangliosides comprise a varied family of glycosphingolipid structures bearing one or more sialic acid residues. They are found in all mammalian tissues but are most abundant in the brain, where they represent the quantitatively major class of sialoglycans.
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Gangliosides comprise a varied family of glycosphingolipid structures bearing one or more sialic acid residues. They are found in all mammalian tissues but are most abundant in the brain, where they represent the quantitatively major class of sialoglycans.
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Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous System
2014Gangliosides are a large group of complex lipids found predominantly on the outer layer of the plasma membranes of cells, and they are particularly concentrated in nerve endings. Their half-life in the nervous system is short, and their membrane composition and content are strictly connected to their metabolism.
M. Aureli +7 more
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2000
Abstract Gangliosides are sialic acid-containing glycosphingolipids primarily found in the plasma membrane of virtually all vertebrate tissues, with particular abundance in the nervous system. A mixture of purified bovine brain gangliosides has been used for the treatment of alcoholic, diabetic, and uremic polyneuropathy; after ...
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Abstract Gangliosides are sialic acid-containing glycosphingolipids primarily found in the plasma membrane of virtually all vertebrate tissues, with particular abundance in the nervous system. A mixture of purified bovine brain gangliosides has been used for the treatment of alcoholic, diabetic, and uremic polyneuropathy; after ...
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[Gangliosides and antibodies to gangliosides in blood serum].
Biokhimiia (Moscow, Russia), 1992The concentration and composition of gangliosides from normal and pathological blood serum of animals and man are reviewed. Data concerning the elevation of the ganglioside content in the serum under malignization are summarized. The appearance of ganglioside-specific antibodies in some pathological states is described.
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