Results 191 to 200 of about 53,157 (259)

Infectious Triggers and Immune Dynamics in Guillain-Barré Syndrome: Revisiting Campylobacter jejuni and the Silent Role of Haemophilus influenzae. [PDF]

Microbiologyopen
Ramesh A, Subbarayan R, Srinivasan D, Balakrishnan R, Shrestha R, Chauhan A.   +5 more
europepmc   +1 more source

Profiling glycosphingolipid changes in mouse and human cellular models of lysosomal free sialic acid storage disorder. [PDF]

Mol Genet Metab Rep
Sabir MS, Dobrenis K, Rha AK, Pollard L, Leoyklang P, Marrero M, Ciccone C, Hackbarth ME, Huizing M, Wang RY, Gahl WA, Platt FM, Malicdan MCV.   +12 more
europepmc   +1 more source

Sialidases as Potential Therapeutic Targets for Treatment of a Number of Human Diseases. [PDF]

Int J Mol Sci
Schengrund CL.
europepmc   +1 more source

Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype-specific, and severity-linked alterations. [PDF]

Alzheimers Dement
Ambaw YA, Ljubenkov PA, Singh S, Hamed A, Boland S, Boxer AL, Walther TC, Farese RV.   +7 more
europepmc   +1 more source

The developmental expression of the cholinergic-specific antigen Chol-1 in the central and peripheral nervous system of the rat

, 1990
Borroni, E., Derrington, E.
core  

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The Biology of Gangliosides.

Advances in Carbohydrate Chemistry and Biochemistry, 2019
Gangliosides comprise a varied family of glycosphingolipid structures bearing one or more sialic acid residues. They are found in all mammalian tissues but are most abundant in the brain, where they represent the quantitatively major class of ...
R. Schnaar
semanticscholar   +1 more source

Ganglioside Storage Diseases

New England Journal of Medicine, 1971
For almost 100 years Tay-Sachs disease was the only ganglioside storage disease known. A second inborn error of ganglioside metabolism, generalized gangliosidosis, was discovered in 1965.13,35 Three additional ganglioside storage diseases have recently been uncovered,4,3,52,66,74 bringing the total to five.36 Of these, three involve storage of ...
openaire   +3 more sources

Gangliosides and hearing

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017
Severe auditory impairment observed in GM3 synthase-deficient mice and humans indicates that glycosphingolipids, especially sialic-acid containing gangliosides, are indispensable for hearing. Gangliosides associate with glycoproteins to form membrane microdomains, the composition of which plays a special role in maintaining the structural and ...
Jin-Ichi, Inokuchi, Shinji, Go, Misato, Yoshikawa, Kevin, Strauss   +3 more
openaire   +2 more sources

Gangliosides of Melanoma

The Journal of Dermatology, 1992
AbstractThe relationships between the ganglioside composition of melanomas and their biologic behavior were investigated. (1) The amount of GM2 and/or GD2 in melanoma cells injected into nude mice correlated with the tumor growth rate. (2) GD2 content of melanoma cell lines correlated with sensitivity to radiation and vincristine. (3) GM2 expression of
T, Tsuchida, Y, Ishibashi
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Gangliosides in Neuroblastomas

Neurochemical Pathology, 1988
Neuroblastomas from children presenting with tumors at various ages and different primary sites (abdominal, adrenals, pelvic, and thoracic) were studied. Analysis of the ganglioside patterns of 53 tumors indicated that patients who were either disease positive 2 yr following surgery or dead of disease, had significantly (p less than 0.005) less GT1b ...
C L, Schengrund, S J, Shochat
openaire   +2 more sources