Results 121 to 130 of about 9,792 (169)

Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor. [PDF]

Neurochem Res, 2021
Jia Y, Zhang D, Yin H, Li H, Du J, Bao H.   +5 more
europepmc   +1 more source

Dual inhibitory potential of ganoderic acid A on GLUT1/3: computational and in vitro insights into targeting glucose metabolism in human lung cancer. [PDF]

RSC Adv
Bashir MA, Abdalla M, Shao CS, Wang H, Bondzie-Quaye P, Almahi WA, Swallah MS, Huang Q.   +7 more
europepmc   +1 more source

In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes. [PDF]

Pharm Biol, 2020
Xu S, Zhang F, Chen D, Su K, Zhang L, Jiang R.   +5 more
europepmc   +1 more source

Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning. [PDF]

Am J Transl Res
Xiao C, Huang G, Cao X, Li X.
europepmc   +1 more source

Corrigendum to: Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells. [PDF]

Aging Cell, 2022
europepmc   +1 more source

Ganoderic Acid A Metabolites and Their Metabolic Kinetics [PDF]

Frontiers in Pharmacology, 2017
Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. The present study aims (1) to identify GAA metabolites, in vivo by analyzing the bile, plasma and urine after intravenous administration to rats (20 mg ...
, Qi Chang, Lisha Wang
exaly   +3 more sources

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Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitor

Bioorganic and Medicinal Chemistry Letters, 2009
Prostate cancer is the most common cancer in men in Western countries, with a high incidence of bone metastasis. Ganoderic acid DM, with 5alpha-reductase inhibitory and androgen receptor (AR) binding activity, isolated from the ethanol extracts of Ganoderma lucidum, can inhibit prostate cancer cell growth and block osteoclastogenesis.
Kuniyoshi Shimizu, Akiko Kukita, Ryuichiro Kondo   +2 more
exaly   +3 more sources

Protective effect of Ganoderic acid A on adjuvant-induced arthritis

Immunology Letters, 2020
The purpose of the experiment was to explore the effect of Ganoderic acid A (GAA) on adjuvant-induced arthritis in rats. In this study, the rat model of collagen-induced rheumatoid arthritis (CIA) was established with type II collagen plus Freund's complete adjuvant. Arthritis index, joint pathology, toe swelling, hemorheology, synovial cell apoptosis,
Tao, Cao, Chuanfeng, Tang, Lezhen, Xue, Mingzhu, Cui, Dan, Wang   +4 more
openaire   +2 more sources

Biotechnological production and application of ganoderic acids

Applied Microbiology and Biotechnology, 2010
Ganoderic acids (GAs), a kind of highly oxygenated lanostane-type triterpenoids, are important bioactive constituents of the famous medicinal mushroom Ganoderma lucidum. They have received wide attention in recent years due to extraordinarily pharmacological functions. Submerged fermentation of G.
Jun-Wei, Xu, Wei, Zhao, Jian-Jiang, Zhong   +2 more
openaire   +2 more sources

Ganoderic Acid and Lucidenic Acid (Triterpenoid)

2014
Ganoderma species is known as a functional mushroom used in many Asian countries. Triterpenoids, ganoderic acids, and lucidenic acids have been isolated from Ganoderma species (Ganodermataceae family), such as Ganoderma lucidum. Triterpenoids have been investigated for their biological activities, including antibacterial, antiviral, antitumor ...
Chin-Lin, Hsu, Gow-Chin, Yen
openaire   +2 more sources