Results 91 to 100 of about 886,070 (201)

MOESM1 of Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum

, 2019
Additional file 1: Figure S1. (A) The expression vector pJW-EXP-FPS. (B) Identification and characterization of the FPF gene-overexpressing strain. Amplification pattern of genomic PCR obtained with primers for the fusion of the gpd promoter and FPS gene fragment from different strains.
Fei, Yu, Li, Na, Zhang, De-Huai, Xu, Jun-Wei   +3 more
openaire   +1 more source

Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study

Tumor Biology, 2016
Receptor tyrosine kinases (RTKs) are transmembrane high-affinity surface receptors responsible for cell migration, adhesion, apoptosis, metabolism, and cell proliferation activities in various cancers. Minute aberration in the RTK signaling modulates the downstream signaling pathways that results in cancer.
Balraj Singh, Gill, , Navgeet, Sanjeev, Kumar   +2 more
openaire   +2 more sources

In vitro effects of Ganoderic acid A on NF-κB-mediated inflammatory response in caerulein-stimulated pancreatic acinar cells

Signa Vitae
This study aimed to investigate Ganoderic acid A’s (GAA) possible effects on inflammation and oxidative stress of caerulein-stimulated pancreatic acinar cells and uncover its effects on acute pancreatitis (AP).
Yuzhou Jin, Jin Huang, N. Ma
semanticscholar   +1 more source

Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression

Neuropsychiatric Disease and Treatment, 2021
Ling Zhang,1 Lei Zhang,2 Rubo Sui1 1Department of Neurology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China; 2College of Nursing, Jinzhou Medical University, Jinzhou, People’s Republic of ...
Zhang L, Zhang L, Sui R
doaj  

A novel molecular imprinted electrochemical biosensor for sensitive determination of Ganoderic acid A

Journal of Physics, Conference Series
Analytical approaches with the features of easy manipulation, cost-effectiveness, and miniature are needed for practice-oriented point-of-care diagnostics.
Wenwei Li, Yao Xie, Axin Liang
semanticscholar   +1 more source

Anticancer Activity of Ganoderic Acid DM: Current Status and Future Perspective

Journal of Clinical & Cellular Immunology, 2017
Ganoderma lucidum is a mushroom that has a long history of medicinal use in the Far East countries as this mushroom is revered for its supposed miracle cures and life improving properties. Recently, this mushroom has come under scientific scrutiny to examine the possibility of finding biologically active compounds that may have an impact on human ...
Bryant, John Matthew, Bouchard, Mollie, Haque, Azizul   +2 more
openaire   +2 more sources

Effect of selenium on main active component contents of Ganoderma lingzhi in different periods

浙江大学学报. 农业与生命科学版, 2017
Ganoderma lingzhi is one of the important edible and medicinal fungi with broad pharmacological activities, such as anti- tumor, immunity improvement and anti- oxidation, and also rich in selenium. Selenium is an essential trace element.
YE Liyun, XIE Fan, ZHAO Lili, FANG Jingjing, WU Xiaoping   +4 more
doaj   +1 more source

Immunomodulatory Function and Safety Evaluation of Compound Preparation Containing Ganoderma lucidum Polysaccharides

Shipin gongye ke-ji
Objective: To evaluate the immunomodulatory function and safety of compound preparation containing Ganoderma lucidum polysaccharides. Methods: According to the Technical Standards for Testing and Assessment of Health Food (2003 Edition), the ...
Lei WANG, Feng LIANG, Hongwei ZHAO, Deshan NING, Lihua YIN, Xiaomin YE, Guoxiao YIN   +6 more
doaj   +1 more source

Enhanced production of individual ganoderic acids by integrating Vitreoscilla haemoglobin expression and calcium ion induction in liquid static cultures of Ganoderma lingzhi

Microbial Biotechnology, 2019
Summary Ganoderic acids produced by Ganoderma exhibit anticancer and antimetastatic activities. A novel approach by combining Vitreoscilla haemoglobin (VHb) expression and calcium ion induction was developed to enhance ganoderic acid (GA) production in ...
Jun‐Wei Xu, Tong‐Hui Yue, Xuya Yu, Peng Zhao, Tao Li, Na Li   +5 more
doaj   +1 more source

Ganoderic Acid A alleviates ulcerative colitis by inhibiting the interleukin17 signaling pathway via targeting retinoic acid-related orphan receptor alpha.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Ulcerative colitis (UC), a chronic inflammatory bowel disease, poses a significant global public health burden, a challenge compounded by the limited availability of effective treatments.
Yifei Ye, Yinni Chen, Yiyang Cao, Tongzhan Liu, Yu Hu, Xi Chen, Xiangnuo Han, Shu Yang, Shun Li, Yuanli Chen, Meixiu Jiang   +10 more
semanticscholar   +1 more source