Results 91 to 100 of about 10,014 (199)

Sustainable Natural Product Glycosylation: A Critical Evaluation of Biocatalytic and Chemical Approaches

ChemSusChem, Volume 18, Issue 20, October 23, 2025.
Developing a process to produce glycosylated natural products involves many decisions, and given the current climate crisis, the environmental impact of the various processes must be a major consideration. This review provides an overview of the various processes and a framework for which metrics should be quantified to select processes that are both ...
Felipe Mejia‐Otalvaro, Brianna Marie Lax, Onur Kırtel, Ditte Hededam Welner   +3 more
wiley   +1 more source

Supercritical carbon-oxide extracts from cultivated and wild-grown Ganoderma lucidum mushroom: differences in ergosterol and ganoderic acids content, antioxidative and enzyme inhibitory properties

, 2023
In the present study, we investigated the effect of supercritical carbon-oxide (scCO2) extraction on antioxidant capacity, enzyme inhibitory potential, and levels of ergosterol and ganoderic acid in both cultivated and wild-grown G. lucidum.
Svetolik Maksimovic (14571690), Vanja Tadic (844469), Ivan Milovanovic (4567816), Gokhan Zengin (663484)   +3 more
core   +1 more source

Functional Foods Enriched With Bioactive Compounds: Therapeutic Potential and Technological Innovations

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Functional foods enriched with bioactive compounds such as polyphenols, carotenoids, omega‐3 fatty acids, and probiotics provide therapeutic benefits through antioxidant, anti‐inflammatory, and gut‐modulating mechanisms. Advances in biotechnology and AI have improved screening, formulation, and delivery of these compounds in diverse food matrices ...
Zargull Arshad, Shafa Shahid, Ammarah Hasnain, Esha Yaseen, Mehdi Rahimi   +4 more
wiley   +1 more source

Ganoderic acid A alleviate psoriasis by inhibiting GSDMD-mediated pyroptosis

Tissue and Cell
Psoriasis is a chronic inflammatory dermatological condition characterized by the infiltration of inflammatory cells into the dermal layer. This study aimed to elucidate the anti-inflammatory properties and underlying molecular mechanisms of Ganoderic acid A in the treatment of psoriasis.A psoriasis model was induced in mice using IMQ to evaluate the ...
Chenggen Xiao, Junchen Chen, Xingchen Zhou, Hong Liu   +3 more
openaire   +2 more sources

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

Plant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang, Luyao Zhang, Xia Li, Wensong Sun, Yike Wang, Luqi Huang, Juan Wang, Wenyuan Gao, Lanping Guo   +8 more
wiley   +1 more source

Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study

Tumor Biology, 2016
Receptor tyrosine kinases (RTKs) are transmembrane high-affinity surface receptors responsible for cell migration, adhesion, apoptosis, metabolism, and cell proliferation activities in various cancers. Minute aberration in the RTK signaling modulates the downstream signaling pathways that results in cancer.
Balraj Singh, Gill, , Navgeet, Sanjeev, Kumar   +2 more
openaire   +2 more sources

Time course of ganoderic acids and fungal biomass production of Ganoderma lucidum incubated with aspirin.

, 2013
Fungal mycelium was cultured on PDA for 4 days and then incubated with 4 mM aspirin for additional 6 to 48 hr. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs ...
Hui-Chuan Hsieh (289703), Ni Tien (289701), Hong-Zin Lee (280194), Yu-Lin Chung (289705), Lin-Hsien Tseng (289704), Meng-Shiou Lee (289702), Bang-Jau You (276811), Miin-Huey Lee (289700)   +7 more
core   +1 more source

Fig. 5 in Lanostane triterpenoids from cultivated fruiting bodies of Ganoderma sichuanense: Determination of the C-25 absolute configuration of ganoderic acid A and its derivatives using the phenylglycine methyl ester (PGME) method

, 2021
Fig. 5. Δδ-Values (δ(S) – δ(R)) of the bis-MTPA esters 28a/28b.Published as part of Chinthanom, Panida, Srichomthong, Kitlada, Rachtawee, Pranee, Boonpratuang, Thitiya, Choeyklin, Rattaket, Feng, Tao, Liu, Ji-Kai & Isaka, Masahiko, 2021, Lanostane ...
Isaka, Masahiko, Rachtawee, Pranee, Boonpratuang, Thitiya, Chinthanom, Panida, Liu, Ji-Kai, Choeyklin, Rattaket, Srichomthong, Kitlada, Feng, Tao   +7 more
core   +1 more source

Ganoderic Acid X, a Lanostanoid Triterpene, Inhibits Topoisomerases and Induces Apoptosis of Cancer Cells

, 2009
Lanostanoid triterpenes isolated from Ganoderma amboinense were found to inhibit the growth of numerous cancer cell lines, and some of them inhibited the activities of topoisomerases I and II?? in vitro.
方偉宏;蔡克嵩;林淑萍;甘魯生, FANG, WOEI-HORNG;TSAI, KEH-SUNG;LIN, SHWU-BIN;KAN, LOU-SING   +1 more
core   +1 more source

Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression

Neuropsychiatric Disease and Treatment, 2021
Ling Zhang,1 Lei Zhang,2 Rubo Sui1 1Department of Neurology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China; 2College of Nursing, Jinzhou Medical University, Jinzhou, People’s Republic of ...
Zhang L, Zhang L, Sui R
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