Results 81 to 90 of about 10,014 (199)
Interaction of ganoderic acid on HIV related target: molecular docking studies [PDF]
Bioinformation, 2011 Trouver le remède ultime contre le VIH reste une tâche difficile depuis des décennies. Divers composés actifs ont été testés contre divers composants du virus dans le but d'arrêter le développement du virus chez l'hôte infecté. L'idée de trouver un remède à partir de composés naturels pharmacologiquement actifs connus est intrigante et pratique.
Rahmad Akbar, Wai Keat Yam
openaire +2 more sources
Time course of ganoderic acids and fungal biomass production of Ganoderma lucidum cultured on PDA.
, 2013 Ganoderma lucidum was cultured on potato dextrose agar (PDA) for 1 to 6 weeks. Fungal biomass (A), accumulation of lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) (B) and total ganoderic acids (total GAs) (C) were evaluated.
Hui-Chuan Hsieh (289703) +7 more
core +1 more source
Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review
BioMed Research International, Volume 2026, Issue 1, 2026.All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh +3 more
wiley +1 more source
, 2017 Putrescine is an important polyamine that participates in a variety of stress responses. Ornithine decarboxylase (ODC) is a key enzyme that catalyzes the biosynthesis of putrescine. A homolog of the gene encoding ODC was cloned from Ganoderma
Ang Ren +7 more
core +1 more source
, 2023 The repurposing of expired drugs through bioconversion remains one of the most crucial research milestones, as this practice reduces drug contamination while producing compounds of significance.
Kudzanai Tapfuma +4 more
core +1 more source
Food Frontiers, Volume 6, Issue 6, Page 3108-3121, November 2025.Ganoderic acid A (GA) improved lipid metabolism disorders by inhibiting intestinal FXR. GA markedly suppressed the ileal intestinal FXR activity. Then, GA changed bile acid composition and upregulated hepatic Cyp7a1 mRNA through decreasing FXR target genes encoded protein levels.
Feng Lu +7 more
wiley +1 more source
Synthesis of ganoderic acid analogues to investigate their activity as anti-prostate cancer agents [PDF]
, 2019 Cancers are one of the leading causes of premature human death globally. Prostate cancer is the second most common cancer in the world; chemoprevention can help decrease the proportion of fatal cases and prevent recurrence of the cancer.
Al-Obaidi, Mohammed
core
Food Science &Nutrition, Volume 13, Issue 11, November 2025.This study demonstrates that phytofabricated silver nanoparticles (VACAgNPs) from Vaccinium arctostaphylos L. exhibit significant anticancer activity against breast cancer cells, inducing apoptosis and suppressing growth in both hormone‐responsive (MCF‐7) and triple‐negative (4T1, MDA‐MB‐231) subtypes. The nanoparticles enhanced reactive oxygen species
Nazila Soleimani +3 more
wiley +1 more source
Effect of fungal culture age on ganoderic acids induction by aspirin in Ganoderma lucidum.
, 2013 Fungal mycelium cultured on PDA for 4–12 days was incubated with 4 mM aspirin for additional 1 day. Fungal biomass (A), lanosta-7,9(11), 24-trien-3α-o1-26-oic acid (ganoderic acid 24) production (B) and total ganoderic acids (total GAs) production (C) by
Hui-Chuan Hsieh (289703) +7 more
core +1 more source
, 2023 Lanostane-type triterpenoid ganoderic acids (GAs) possess interesting bioactivities, but their efficient biosynthesis remains challenging. CYP512W2, a promiscuous membrane-anchored cytochrome P450, was recently found to oxidize C7 (or C11) and C15 to ...
Zeqian Du (17425639) +6 more
core +1 more source