Results 81 to 90 of about 10,669 (208)
ABSTRACT This study aimed to evaluate the potential of the mycelial growth filtrate (MGF) from Ganoderma lucidum in providing systemic protection to tomato plants against Septoria lycopersici‐induced leaf spot and inhibiting the production of reproductive structures by the phytopathogen. In greenhouse experiments, foliar application of MGF at 40% (v/v)
Mycheli P. Cruz +3 more
wiley +1 more source
Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh +3 more
wiley +1 more source
Ganoderic acid A (GA) improved lipid metabolism disorders by inhibiting intestinal FXR. GA markedly suppressed the ileal intestinal FXR activity. Then, GA changed bile acid composition and upregulated hepatic Cyp7a1 mRNA through decreasing FXR target genes encoded protein levels.
Feng Lu +7 more
wiley +1 more source
Antiviral Agents From Fungi: Diversity, Mechanisms and Potential Applications [PDF]
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Cortina-Escribano, Marta +5 more
core +3 more sources
This study demonstrates that phytofabricated silver nanoparticles (VACAgNPs) from Vaccinium arctostaphylos L. exhibit significant anticancer activity against breast cancer cells, inducing apoptosis and suppressing growth in both hormone‐responsive (MCF‐7) and triple‐negative (4T1, MDA‐MB‐231) subtypes. The nanoparticles enhanced reactive oxygen species
Nazila Soleimani +3 more
wiley +1 more source
Antiangiogenic compounds: well-established drugs versus emerging natural molecules [PDF]
Angiogenesis is the natural and physiologic process of growing blood vessels from pre-existing ones. Pathological angiogenesis occurs when the precise balance of all the molecular pathways that regulate angiogenesis is disrupted, and this process is a ...
Abreu, Rui M.V. +4 more
core +1 more source
Ganoderic acid A (GAA) is a triterpenoid with identified effective activity, isolated from Ganoderma lucidum . Glycosylation of triterpenoid might improve its anti‐toxin bioactivity and also increase both water solubility and physical‐chemical ...
Jiumn-Yih Wu +3 more
openaire +1 more source
Developing a process to produce glycosylated natural products involves many decisions, and given the current climate crisis, the environmental impact of the various processes must be a major consideration. This review provides an overview of the various processes and a framework for which metrics should be quantified to select processes that are both ...
Felipe Mejia‐Otalvaro +3 more
wiley +1 more source
Department of Metabolic Engineering [PDF]
薬物代謝工学部門は和漢薬の薬効,毒性発現に関与する代謝系の分子生物学的研究を発展させることを設置目的とし,①和漢薬の薬効発現に関与する腸内細菌遺伝子の解析,②薬物代謝機能調節遺伝子の解明とその応用,③腎毒性物質産生機構の分子生物学的解明とその制御に関する研究を課題として取りあげ,和漢薬の薬効発現機構,生体へのレスポンスなどの基礎的研究を通じて,和漢薬の科学的評価や臨床応用をはかることを目指している。主な研究題目を以下に示す。1.
中村 憲夫 +3 more
core +2 more sources
Ganoderic acid G and I and ganolucidic acid A and B, new triterpenoids from Ganoderma lucidum.
Four new highly oxidized lanostane-type triterpenoids, ganoderic acid G and I and ganolucidic acid A and B, were isolated from the fungus ganoderma lucidum and their structures were elucidated on the basis of spectral evidence.
Tohru Kikuchi +3 more
openaire +2 more sources

