Results 61 to 70 of about 10,669 (208)

Ganoderic Acid Me Inhibits Tumor Invasion Through Down-Regulating Matrix Metalloproteinases 2/9 Gene Expression

Journal of Pharmacological Sciences, 2008
The effect of ganoderic acid Me (GA-Me), which was purified from the fermentation mycelia of the traditional Chinese medicinal mushroom Ganoderma lucidum as reported (Tang W, Gu TY, Zhong JJ. Biochem Eng J.
Nian-Hong Chen, Jian-Wen Liu, Jian-Jiang Zhong   +2 more
doaj   +1 more source

Effect of Pd-Sensitization on Poisonous Chlorine Gas Detection Ability of TiO₂: Green Synthesis and Low-Temperature Operation

Sensors, 2022
Ganoderma lucidum mushroom-mediated green synthesis of nanocrystalline titanium dioxide (TiO2) is explored via a low-temperature (≤70 °C) wet chemical method. The role of Ganoderma lucidum mushroom extract in the reaction is to release the ganoderic acid
Satish Ekar, Umesh T. Nakate, Yogesh B. Khollam, Shoyebmohamad F. Shaikh, Rajaram S. Mane, Abu ul Hassan S. Rana, Marimuthu Palaniswami   +6 more
doaj   +1 more source

Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells

Life Sciences, 2005
Lanostanoid triterpenes isolated from Ganoderma amboinense were found to inhibit the growth of numerous cancer cell lines, and some of them inhibited the activities of topoisomerases I and IIalpha in vitro. Among the bioactive isolates, one of the most potent triterpene was identified to be 3 alpha-hydroxy-15 alpha-acetoxy-lanosta-7,9(11),24-trien-26 ...
Li, Chyi-Hann, Chen, Pei-Yu, Chang, Ue-Min, Kan, Lou-Sing, Fang, Woei-Horng, Tsai, Keh-Sung, Lin, Shwu-Bin   +6 more
openaire   +2 more sources

Ethanol Extract From Ganoderma atrum Alleviates Obesity Through Modulating Gut Microbiota and Metabolism

Food Frontiers, Volume 7, Issue 2, March 2026.
EEG potentially exerts anti‐obesity effects by reducing the abundance of Lactobacillus, which subsequently elevates the levels of conjugated bile acids. ABSTRACT Obesity is a serious public health challenge, underscoring the importance of developing natural and effective interventions.
Qiuyue Fang, Chenqing Xu, Siying Wu, Steve W. Cui, Shaoping Nie   +4 more
wiley   +1 more source

Self-assembled thermal gold nanorod-loaded thermosensitive liposome-encapsulated ganoderic acid for antibacterial and cancer photochemotherapy

Artificial Cells, Nanomedicine, and Biotechnology, 2019
A novel nanoparticle (Au-LTSL-GA.A) uses the thermosensitive liposome (LTSL) to encapsulate ganoderic acid A (GA.A), which successfully transforms the polarity of GA.A and has excellent water solubility. The multifunctional Au-LTSL-GA.A, a self-assembled
Weiwei Zhang, Wenwen Yu, Xiaoyuan Ding, Chenyang Yin, Jing Yan, Endong Yang, Feng Guo, Dongdong Sun, Weiyun Wang   +8 more
doaj   +1 more source

Low molecular weight compounds from mushrooms as potential Bcl-2 inhibitors: docking and virtual screening studies [PDF]

, 2016
Mestrado com dupla diplomação com o Institut Superieur de Biotechnologie de MonastirMushrooms have the ability to promote apoptosis in tumor cell lines, but the mechanism of action is not quite well understood. Inhibition of the interaction between Bcl-2
Khelifa, Sabrine
core  

Application of Electronic tongue and HPLC in rapid determination of functional triterpenes and origins of Ganoderma lucidum

Frontiers in Nutrition
IntroductionGanoderma lucidum is one well known functional food resource. The triterpenes, such as Ganoderic acid A and Ganoderic acid D, as well as the sensory characteristics could reflect the quality of G. lucidum.MethodsIn order to find rapid methods
Jing Tian, Jing Tian, Jinfeng Wei, Yuxin Liu, Yuxin Liu, Changqin Li, Changqin Li, Changqin Li, Changqin Li, Changyang Ma, Changyang Ma, Changyang Ma, Changyang Ma, Wenyi Kang, Wenyi Kang, Wenyi Kang, Wenyi Kang   +16 more
doaj   +1 more source

Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma with Ganoderma lucidum Extracts

Molecules, 2019
Mycotherapy has been shown to improve the overall response rate during cancer treatment and reduce some chemotherapy-related adverse events. Ganoderma lucidum is a traditional mushroom used for pharmaceutical purposes. G.
Sora Huh, Seulki Lee, Su Jin Choi, Zhexue Wu, Jae-Han Cho, Lina Kim, Yu Su Shin, Byung Woog Kang, Jong Gwang Kim, Kwanghyeon Liu, Hyosun Cho, Hyojeung Kang   +11 more
doaj   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

High Oxygen Treatments Enhance the Contents of Phenolic Compound and Ganoderic Acid, and the Antioxidant and DNA Damage Protective Activities of Ganoderma lingzhi Fruiting Body

Frontiers in Microbiology, 2019
Ganoderma lingzhi is a famous medicinal mushroom used as Chinese medicine or functional food and has been accepted across the globe. It is important to enhance the contents of bioactive compounds, which in turn improves the quality and biological ...
Qingying Dong, Yueyue Li, Gaoqiang Liu, Zhiwei Zhang, Huabin Zhou, Hailong Yang   +5 more
doaj   +1 more source