Results 51 to 60 of about 886,070 (201)

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer

Tumor Biology, 2017
Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and exogenous stress by activating ...
Balraj Singh Gill, Sanjeev Kumar, Navgeet   +2 more
doaj   +1 more source

Synergistic effect of Ganoderma lucidum Triterpenoids and biosynthesized Zinc Oxide nanoparticles against some dermatophytes [PDF]

Nanomedicine Research Journal
G. lucidum mushroom has been recorded in conventional medicine for more than 2000 years due to has several bioactive compounds including triterpenoids (GLTs).
Hasan Kareem, Alaa Mohsin Al-Araji
doaj   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao, Xiao‐li Dong, Rui‐ting Li, Qu‐huan Ma, Xiao‐feng Shi   +4 more
wiley   +1 more source

The Potential Alleviating Property Against NAFLD by Ganoderma lucidum With Bacteria‐Enzyme Synergistic Fermentation

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
A bacteria‐enzyme synergistic fermentation process using Lactobacillus rhamnosus was developed to produce fermented Ganoderma lucidum broth (FBG), which significantly enriched ganoderic acid F compared to water extraction. In FFA‐induced HepG2 cells, FBG alleviated NAFLD‐related damage by reducing lipid deposition, ROS, MDA, TC, TG, and LDL‐C, while ...
Manhui Sun, Kecheng Li, Zhenzhen Wang, Jing Dai, Jianwei Mao, Min Cai, Ruyi Sha   +6 more
wiley   +1 more source

Ganoderic Acid Me Inhibits Tumor Invasion Through Down-Regulating Matrix Metalloproteinases 2/9 Gene Expression

Journal of Pharmacological Sciences, 2008
The effect of ganoderic acid Me (GA-Me), which was purified from the fermentation mycelia of the traditional Chinese medicinal mushroom Ganoderma lucidum as reported (Tang W, Gu TY, Zhong JJ. Biochem Eng J.
Nian-Hong Chen, Jian-Wen Liu, Jian-Jiang Zhong   +2 more
doaj   +1 more source

Target specific inhibition of West Nile virus envelope glycoprotein and methyltransferase using phytocompounds: an in silico strategy leveraging molecular docking and dynamics simulation

Frontiers in Microbiology, 2023
Mosquitoes are the primary vector for West Nile virus, a flavivirus. The virus’s ability to infiltrate and establish itself in increasing numbers of nations has made it a persistent threat to public health worldwide.
Shopnil Akash, Imren Bayıl, Md. Anisur Rahman, Nobendu Mukerjee, Nobendu Mukerjee, Swastika Maitra, Md. Rezaul Islam, Sanchaita Rajkhowa, Arabinda Ghosh, Sami A. Al-Hussain, Magdi E. A. Zaki, Vikash Jaiswal, Sanjit Sah, Sanjit Sah, Joshuan J. Barboza, Ranjit Sah, Ranjit Sah, Ranjit Sah   +17 more
doaj   +1 more source

Comprehensive Evaluation of Fructus Tsaoko, Seeds of Tsaoko Fructus and Ginger Made Seeds of Tsaoko Fructus Based on Drug‐Like Compounds and Aroma Analysis

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This study mainly consists of two parts. First, after screening for drug‐like metabolites via LC–MS and GC–MS, a comprehensive evaluation model was established using a principal component analysis‐based weighted scoring method, by which the drug‐likeness ranking of three samples was determined.
Han Chen, Meiquan Yang, Weize Yang, Mingju Qi, Zongliang Xu, Tianmei Yang, Jinyu Zhang   +6 more
wiley   +1 more source

Application of Electronic tongue and HPLC in rapid determination of functional triterpenes and origins of Ganoderma lucidum

Frontiers in Nutrition
IntroductionGanoderma lucidum is one well known functional food resource. The triterpenes, such as Ganoderic acid A and Ganoderic acid D, as well as the sensory characteristics could reflect the quality of G. lucidum.MethodsIn order to find rapid methods
Jing Tian, Jing Tian, Jinfeng Wei, Yuxin Liu, Yuxin Liu, Changqin Li, Changqin Li, Changqin Li, Changqin Li, Changyang Ma, Changyang Ma, Changyang Ma, Changyang Ma, Wenyi Kang, Wenyi Kang, Wenyi Kang, Wenyi Kang   +16 more
doaj   +1 more source

Self-assembled thermal gold nanorod-loaded thermosensitive liposome-encapsulated ganoderic acid for antibacterial and cancer photochemotherapy

Artificial Cells, Nanomedicine, and Biotechnology, 2019
A novel nanoparticle (Au-LTSL-GA.A) uses the thermosensitive liposome (LTSL) to encapsulate ganoderic acid A (GA.A), which successfully transforms the polarity of GA.A and has excellent water solubility. The multifunctional Au-LTSL-GA.A, a self-assembled
Weiwei Zhang, Wenwen Yu, Xiaoyuan Ding, Chenyang Yin, Jing Yan, Endong Yang, Feng Guo, Dongdong Sun, Weiyun Wang   +8 more
doaj   +1 more source