Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma. [PDF]
Wang B +15 more
europepmc +1 more source
Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi. [PDF]
Liu YN +6 more
europepmc +1 more source
Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor. [PDF]
Jia Y +5 more
europepmc +1 more source
The Efficacy & Molecular Mechanisms of a Terpenoid Compound Ganoderic Acid C1 on Corticosteroid-Resistant Neutrophilic Airway Inflammation: In vivo and in vitro Validation. [PDF]
Wang ZZ +11 more
europepmc +1 more source
In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes. [PDF]
Xu S +5 more
europepmc +1 more source
Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning. [PDF]
Xiao C, Huang G, Cao X, Li X.
europepmc +1 more source
Corrigendum to: Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells. [PDF]
europepmc +1 more source
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Ganoderic acid A: an in-depth review of pharmacological effects and molecular docking analysis.
Journal of EthnopharmacologyETHNOPHARMACOLOGICAL RELEVANCE Ganoderic acid A (GAA, C30H44O7) is one of the most abundant and active components of Ganoderic acids (GAs). GAs are highly oxidized tetracyclic triterpenoid compounds mainly derived from Ganoderma lucidum (Curtis) P. Karst
Qi Sui +8 more
semanticscholar +3 more sources
BACKGROUND Hepatoblastoma (HB) is the most prevalent primary liver malignancy in children and is characterized by aggressive progression and suboptimal therapeutic outcomes.
Hang Song +10 more
semanticscholar +3 more sources
Ganoderic Acid A Metabolites and Their Metabolic Kinetics [PDF]
Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. The present study aims (1) to identify GAA metabolites, in vivo by analyzing the bile, plasma and urine after intravenous administration to rats (20 mg ...
, Qi Chang, Lisha Wang
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