Results 151 to 160 of about 10,014 (199)

Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma. [PDF]

Saudi Pharm J, 2021
Wang B, Sun L, Wen M, Tan Y, Almalki WH, Katouah H, Kazmi I, Afzal O, Altamimi ASA, Al-Abbasi FA, Alrobaian M, Alharbi KS, Alenezi SK, Alghaith AF, Beg S, Rahman M.   +15 more
europepmc   +1 more source

Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi. [PDF]

Commun Biol
Liu YN, Chen YL, Zhang ZJ, Wu FY, Wang HJ, Wang XL, Liu GQ.   +6 more
europepmc   +1 more source

Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor. [PDF]

Neurochem Res, 2021
Jia Y, Zhang D, Yin H, Li H, Du J, Bao H.   +5 more
europepmc   +1 more source

Dual inhibitory potential of ganoderic acid A on GLUT1/3: computational and in vitro insights into targeting glucose metabolism in human lung cancer. [PDF]

RSC Adv
Bashir MA, Abdalla M, Shao CS, Wang H, Bondzie-Quaye P, Almahi WA, Swallah MS, Huang Q.   +7 more
europepmc   +1 more source

In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes. [PDF]

Pharm Biol, 2020
Xu S, Zhang F, Chen D, Su K, Zhang L, Jiang R.   +5 more
europepmc   +1 more source

Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning. [PDF]

Am J Transl Res
Xiao C, Huang G, Cao X, Li X.
europepmc   +1 more source

Corrigendum to: Ganoderic acid D prevents oxidative stress-induced senescence by targeting 14-3-3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells. [PDF]

Aging Cell, 2022
europepmc   +1 more source

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Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitor

Bioorganic and Medicinal Chemistry Letters, 2009
Prostate cancer is the most common cancer in men in Western countries, with a high incidence of bone metastasis. Ganoderic acid DM, with 5alpha-reductase inhibitory and androgen receptor (AR) binding activity, isolated from the ethanol extracts of Ganoderma lucidum, can inhibit prostate cancer cell growth and block osteoclastogenesis.
Kuniyoshi Shimizu, Akiko Kukita, Ryuichiro Kondo   +2 more
exaly   +3 more sources

Protective effect of Ganoderic acid A on adjuvant-induced arthritis

Immunology Letters, 2020
The purpose of the experiment was to explore the effect of Ganoderic acid A (GAA) on adjuvant-induced arthritis in rats. In this study, the rat model of collagen-induced rheumatoid arthritis (CIA) was established with type II collagen plus Freund's complete adjuvant. Arthritis index, joint pathology, toe swelling, hemorheology, synovial cell apoptosis,
Tao, Cao, Chuanfeng, Tang, Lezhen, Xue, Mingzhu, Cui, Dan, Wang   +4 more
openaire   +2 more sources

Biotechnological production and application of ganoderic acids

Applied Microbiology and Biotechnology, 2010
Ganoderic acids (GAs), a kind of highly oxygenated lanostane-type triterpenoids, are important bioactive constituents of the famous medicinal mushroom Ganoderma lucidum. They have received wide attention in recent years due to extraordinarily pharmacological functions. Submerged fermentation of G.
Jun-Wei, Xu, Wei, Zhao, Jian-Jiang, Zhong   +2 more
openaire   +2 more sources