Results 51 to 60 of about 6,644,990 (199)
Vps54 is a subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN).
Prajal H. Patel +5 more
doaj +1 more source
Generating primordial germ cell-like cells (PGCLCs) from human pluripotent stem cells (hPSCs) advances studies of human reproduction and development of infertility treatments, but often entails complex 3D aggregates.
Sivakamasundari Vijayakumar +11 more
doaj +1 more source
The GARP/Latent TGF‐β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance [PDF]
Treg cells can secrete latent TGF‐β1 (LTGF‐β1), but can also utilize an alternative pathway for transport and expression of LTGF‐β1 on the cell surface in which LTGF‐β1 is coupled to a distinct LTGF‐β binding protein termed glycoprotein A repetitions predominant (GARP)/LRRC32. The function of the GARP/LTGF‐β1 complex has remained elusive.
J. Edwards +5 more
semanticscholar +3 more sources
Microbial dysbiosis in the upper digestive tract is linked to an increased risk of esophageal squamous cell carcinoma (ESCC). Overabundance of Porphyromonas gingivalis is associated with shorter survival of ESCC patients.
Yi-Jun Qi +19 more
doaj +1 more source
Radial or bilateral? The molecular basis of floral symmetry. [PDF]
In the plant kingdom, the flower is one of the most relevant evolutionary novelties. Floral symmetry has evolved multiple times from the ancestral condition of radial to bilateral symmetry.
ACETO, SERENA +2 more
core +1 more source
Vps51p Mediates the Association of the GARP (Vps52/53/54) Complex with the Late Golgi t-SNARE Tlg1p [PDF]
Multisubunit tethering complexes may contribute to the specificity of membrane fusion events by linking transport vesicles to their target membrane in an initial recognition event that promotes SNARE assembly. However, the interactions that link tethering factors to the other components of the vesicle fusion machinery are still largely unknown. We have
Elizabeth, Conibear +2 more
openaire +2 more sources
Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells
The conserved oligomeric complex (COG) is a multi-subunit vesicle tethering complex that functions in retrograde trafficking at the Golgi. We have previously demonstrated that the formation of enlarged endo-lysosomal structures (EELSs) is one of the ...
Zinia D’Souza +4 more
doaj +1 more source
Plants generate their reproductive organs, the stamens and the carpels, de novo within the flowers that form when the plant reaches maturity. The carpels comprise the female reproductive organ, the gynoecium, a complex organ that develops along several ...
Lynne Hagelthorn +4 more
doaj +1 more source
Lead Toxicity in Cereals: Mechanistic Insight Into Toxicity, Mode of Action, and Management
Cereals are the major contributors to global food supply, accounting for more than half of the total human calorie requirements. Sustainable availability of quality cereal grains is an important step to address the high-priority issue of food security ...
Muhammad Aslam +7 more
doaj +1 more source
Tethering complexes in the Arabidopsis endomembrane system
Targeting of endomembrane transport containers is of the utmost importance for proper land plant growth and development. Given the immobility of plant cells, localized membrane vesicle secretion and recycling are amongst the main processes guiding proper
Nemanja eVukasinovic, Viktor eZarsky
doaj +1 more source

