Results 161 to 170 of about 849 (195)
Journal of Diabetes, Volume 18, Issue 3, March 2026.OCT imaging assessments and visual tests, which were validated by pyroptosis of retinal ganglion cells (RGC) and upregulation of NLRP3 and GSDMD expression, established an early structure‐function‐pathology diabetic optic neuropathy (DON) model in high glucose & obesity mice. Early retinal nerve fiber layer (RNFL)/total retinal thickness (TRT) thinning
Jingyuan Zhu +3 more
wiley +1 more source
ALDH2 Mediated Ferroptosis Regulation in Ischemia–Reperfusion Injury
Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.ABSTRACT Ischemia–reperfusion injury (IRI) is a common complication in diverse clinical settings, including myocardial infarction, stroke, organ transplantation and major surgery. Its pathological core lies in the metabolic disruption caused by blood flow cessation, followed by oxidative stress, inflammatory cascades and cell death upon reperfusion ...
Liang Han, Wen Zhai
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Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.ABSTRACT Ulcerative colitis (UC) is a chronic, inflammatory bowel disease with limited clinical treatment. Traditional Chinese medicinal ingredients honokiol and magnolol have potential anti‐inflammatory and gastrointestinal protective effects. However, their anti‐inflammatory potential has not been investigated in UC.
Zhaoxu Cai +5 more
wiley +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Journal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 880-894, March 2026.Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
Folinic Acid Improves Healing of Diabetic Foot Ulcers
Wound Repair and Regeneration, Volume 34, Issue 2, March/April 2026.ABSTRACT A novel folinic acid (FA) wound treatment (FAWT) significantly (p < 0.05) improved healing (re‐epithelialization) of chronic diabetic foot ulcers (DFUs). In a double‐blind RCT, 10 (n = 10) chronic DFU subjects received daily topical treatment in either the Control group [(n = 5); PluroGel] or the FAWT group [(n = 5); PluroGel with FA 2.5 ...
Glenn D. Hoke +5 more
wiley +1 more source
Harnessing cell death vulnerabilities for the treatment of Small Cell Lung Cancer [PDF]
Regulated cell death is an essential process in multicellular organisms, necessary for development and critical for pathogen responses. Apoptosis, justifiably the most studied regulated cell death process, rids the body of old and damaged cells via the ...
Valdez Capuccino, Lucas
core
Unraveling Endocannabinoid Signaling Pathways in Cisplatin‐Induced Ototoxicity
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.We performed a comprehensive molecular profiling of the endocannabinoid (eCB) system (ECS) in an auditory Hair cell (HC)‐like cell line (1). Afterwards, we developed suitable in vitro and in vivo models of cisplatin‐induced ototoxicity where we identified distinct components of the ECS (CB2R, DAGLβ and ABHD6) as molecular targets of the drug (2 ...
Sakthimala Palaniappan +12 more
wiley +1 more source
Mitoxyperilysis: A Milestone Discovery in the Field of Cell Death
MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
Maochen Li, Yuhan Niu, Pengtao Jiao
wiley +1 more source
Correction to “Gasdermin D mutation protects against renal ischemia reperfusion injury”
Physiological Reports, Volume 14, Issue 6, March 2026.
wiley +1 more source