Phase II study of 5-fluorouracil and folinic acid in the treatment of patients with advanced gastric cancer. A southwest oncology group study [PDF]
, 1995 Jeffrey L. Berenberg +7 more
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Influence of experimental hypokinesia on gastric secretory function [PDF]
The gastric secretory function of rats was studied in 4, 8, 16 and 30 day hypokinesia. Inhibition of both the gastric juice secretory and acid producing functions was found. The greatest inhibition was observed on day 8 of limited mobility.
Markova, O. O. +3 more
core +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Advanced Science, EarlyView.Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang +9 more
wiley +1 more source
[Role of Potassium-competitive Acid Blockers in the Treatment of Gastric Acid-related Disorders]. [PDF]
Korean J Helicobacter Up Gastrointest Res, 2023 Cho MY, Cho YK.
europepmc +1 more source
Failure of the inhibition of rat gastric mucosal 5‐lipoxygenase by novel acetohydroxamic acids to prevent ethanol‐induced damage [PDF]
, 1988 N. K. Boughton-Smith +1 more
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PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
Advanced Science, EarlyView.This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
The Effect of Gastric Acid on the Surface Properties of Different Universal Composites: A SEM Study. [PDF]
Scanning, 2022 Alp CK, Gündogdu C, Ahısha CD.
europepmc +1 more source