Results 211 to 220 of about 725,921 (266)

Gastric Inhibitory Polypeptide

Clinics in Gastroenterology, 1980
The available data show that GIP is at present the strongest candidate for the insulin-secreting factor of the gut named incretin. Its release is triggered by the absorption of ingested nutrients. GIP acts on the B-cells of the pancreas by potentiating glucose-induced insulin secretion. The role of GIP as an enterogastrone is less well established. The
R, Ebert, W, Creutzfeldt
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Gastric Inhibitory Polypeptide

Comprehensive Physiology, 1989
Abstract The sections in this article are: Gastric Inhibitory Effect of Gastric Inhibitory Polypeptide Insulinotropic Action of GIP
John C Brown, Alison M. J. Buchan, Christopher H. S. McIntosh, Raymond A. Pederson   +3 more
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Clinical studies with gastric inhibitory polypeptide

World Journal of Surgery, 1979
AbstractIntravenous infusion of porcine GIP in man induces insulin release when a degree of hyperglycemia is present. This glucose‐dependent insulinotropic response occurs when a dose of GIP is administered to obtain circulating levels of approximately 1 ng/ml, a physiologic level that can be achieved by the ingestion of glucose or corn oil or a mixed ...
J C, Brown, S, Otte
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Immunoreactive Gastric Inhibitory Polypeptide*

Endocrine Reviews, 1988
IN 1906 extracts of mucosa from the upper small intestine from pigs were tested as a treatment of diabetes in the hope that “the internal secretion of the pancreas might be stimulated and initiated by the substance of the nature of a hormone yielded by the duodenal mucous membrane” (1).
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Identification and Actions of Gastric Inhibitory Polypeptide

1975
Publisher Summary This chapter gives an overview of the identification and actions of gastric inhibitory polypeptide (GIP). It describes an experiment in which it is concluded that exogenous or endogenous GIP is capable of insulinotropic effects in normal man and can lead to substantial acceleration of the disposal of glucose.
J C, Brown, J R, Dryburgh, S A, Ross, J, Dupré   +3 more
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Gastric Inhibitory Polypeptide (GIP)

1988
Publisher Summary This chapter describes two apparently unrelated physiological phenomena for a single peptide that is gastric inhibitory polypeptide (GIP). These physiological actions are the inhibition of gastric acid secretion and stimulation of insulin release. GIP is a major hormone involved in the gastrointestinal regulation of insulin release,
J.C. Brown, C.H.S. McIntosh, R.A. Pederson   +2 more
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The Hepatic Extraction of Gastric Inhibitory Polypeptide and Insulin*

Endocrinology, 1984
The hepatic extractions of gastric inhibitory polypeptide (GIP) and insulin were determined using in vitro and in vivo methods to assess the role of the liver in GIP metabolism and the possible effect of GIP on the hepatic extraction of insulin. During in vitro studies using the isolated perfused rat liver, infusion of GIP (2000 pg/ml) alone and in ...
J B, Hanks, D K, Andersen, J E, Wise, W S, Putnam, W C, Meyers, R S, Jones   +5 more
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A RADIOIMMUNOASSAY OF GASTRIC INHIBITORY POLYPEPTIDE IN HUMAN PLASMA

Journal of Endocrinology, 1980
Abstract A sensitive radioimmunoassay for the measurement of human gastric inhibitory polypeptide (GIP), using pure porcine GIP, has been developed. Cross-reactivity of the antiserum with all available mammalian gut peptide preparations was negligible with the exception of glucagon when it was approximately 1%.
D L, Sarson, M G, Bryant, S R, Bloom
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Glucagon, gastric inhibitory polypeptide and the gastrocolic response

The American Journal of Surgery, 1982
Serosal bipolar electrodes and strain gauge force transducers were placed on the right and left colon in subhuman primates to record spike discharges and circular muscular contractions. The effect of glucagon on colonic motor and electrical activity were studied before and after meals.
J A, Strom, R E, Condon, W J, Schulte, V, Cowles, V L, Go   +4 more
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Cholecystokinin and gastric inhibitory polypeptide not glucagonotropic in dogs

Journal of Surgical Research, 1980
Abstract The role of cholecystokinin (CCK) and gastric inhibitory polypeptide (GIP) as stimulators of glucagon secretion under physiologic conditions is uncertain. Previous studies have utilized CCK preparations now known to have been contaminated with GIP and possibly other gastrointestinal peptides.
K R, Sirinek, B A, Levine, S E, Crockett, S, Cataland   +3 more
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