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Determinants of gastric inhibitory polypeptide and insulin secretion
Metabolism, 1981The plasma concentrations of gastric inhibitory polypeptide (IR-GIP), insulin, and glucose were measured in 5 dogs after administration of various constituents of food. IR-GIP responses produced by galactose and fructose were minimal compared to those of glucose.
R H, Williams, J M, May, J B, Biesbroeck
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Gastric Inhibitory Polypeptide: the neglected incretin revisited
Regulatory Peptides, 2002After the ingestion of fat- and glucose-rich meals, gut hormones are secreted into the circulation in order to stimulate insulin secretion. This so-called "incretin effect" is primarily conferred by Glucagon-like peptide 1 (GLP-1) and Gastric Inhibitory Polypeptide (GIP).
Juris J, Meier +3 more
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Gastric Inhibitory Polypeptide
Archives of Surgery, 1974Gastric inhibitory polypeptide (GIP), immunoreactive insulin (IRI), and glucose levels in response to orally administered glucose were determined in ten patients with vagotomy and pyloroplasty (V&P) and in 21 normal subjects. The V&P patients had the expected early and exaggerated increase in mean serum glucose with a subsequent decline to a level ...
N R, Thomford +4 more
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The evaluation of gastric inhibitory polypeptide (GIP) as the enterogastrone
Journal of Surgical Research, 1979In 1886 Ewald and Boas [4] first showed that olive oil added to a test meal of starch paste given to human subjects inhibited both gastric emptying and acid secretion. Pavlov and his pupil Babkin (1928) later showed that this effect was of duodenal rather than of gastric origin.
P, Soon-Shiong, H T, Debas, J C, Brown
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Gastric Inhibitory Polypeptide (GIP) in Chronic Pancreatitis
The Journal of Clinical Endocrinology & Metabolism, 1976The plasma gastric inhibitory polypeptide (GIP), pancreatic glucagon-like immunoreactivity (PGLI), and gut glucagon-like immunoreactivity (GGLI) responses to oral glucose have been measured in five patients with chronic pancreatitis (with diabetic glucose tolerance tests) and in matched nondiabetic controls. Plasma GIP levels rise rapidly after glucose
J L, Botha, A I, Vinik, J C, Brown
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Gastric Inhibitory Polypeptide in Obesity and Diabetes Mellitus*
The Journal of Clinical Endocrinology & Metabolism, 1984Gastric inhibitory polypeptide (GIP) concentrations may be influenced by obesity, diabetes, and glucagon deficiency and be under feedback inhibition by insulin. To assess these factors, insulin-dependent diabetic, totally pancreatectomized diabetic, and lean and obese noninsulin-dependent diabetic patients were studied twice, once during partial ...
F J, Service +5 more
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Glucagon, gastric inhibitory polypeptide and the gastrocolic response
The American Journal of Surgery, 1982Serosal bipolar electrodes and strain gauge force transducers were placed on the right and left colon in subhuman primates to record spike discharges and circular muscular contractions. The effect of glucagon on colonic motor and electrical activity were studied before and after meals.
J A, Strom +4 more
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Gastric inhibitory polypeptide and gastric acid secretion in pregnant rats
Placenta, 1995The effects of pregnancy on the basal and pentagastrin-stimulated gastric acid secretion and the level of plasma gastric inhibitory polypeptide (GIP) in rats were studied on pentobarbital-anaesthetized non-pregnant rats and rats in the 1st, 2nd, or 3rd week of gestation. Acid output was determined by titration of the gastric perfusate.
T S, Chen +9 more
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