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Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin +2 more
wiley +1 more source
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella +8 more
wiley +1 more source
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Seminars in Cancer Biology, 2022
The discovery of Helicobacter pylori in 1982 drew to an end the stomach being considered as a sterile organ. Later, the progress in molecular methods, especially Next Generation Sequencing and metagenomics, has highlighted the fact that a diverse microbiota including five major phyla could also be present in the stomach.
Emilie Bessède, Francis Megraud
exaly +3 more sources
The discovery of Helicobacter pylori in 1982 drew to an end the stomach being considered as a sterile organ. Later, the progress in molecular methods, especially Next Generation Sequencing and metagenomics, has highlighted the fact that a diverse microbiota including five major phyla could also be present in the stomach.
Emilie Bessède, Francis Megraud
exaly +3 more sources
Helicobacter pylori and the gastric microbiota
Bailliere's Best Practice and Research in Clinical Gastroenterology, 2013The human microbiota along the gastrointestinal tract is currently extensively studied and a number of studies focuses on elucidating the association between a more or less diverse intestinal microbial community and health and disease. The human stomach is considered to be exclusively inhabited by Helicobacter pylori and further lacks a colonizing non ...
Lars Engstrand
exaly +4 more sources
The influence of the gastric microbiota in gastric cancer development
Best Practice & Research Clinical Gastroenterology, 2021Colonization of the stomach by Helicobacter pylori is the trigger for a series of gastric mucosal changes that culminate in gastric cancer. Infection with this bacterium is considered the major risk factor for this malignancy. The introduction of high-throughput sequencing technologies coupled to advanced computational pipelines offered an improved ...
Joana Pereira-Marques +3 more
openaire +2 more sources
Helicobacter, 2015
AbstractAfter the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture‐independent methods of analysis, a non‐H.
Gianluca Ianiro +2 more
exaly +3 more sources
AbstractAfter the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture‐independent methods of analysis, a non‐H.
Gianluca Ianiro +2 more
exaly +3 more sources
The relationship between gastric microbiota and gastric disease
Scandinavian Journal of Gastroenterology, 2019Traditionally, the stomach was believed to be a sterile organ unsuitable for microbiota growth. However, the discovery of H. pylori subverted this conception. With the development of molecular techniques, an abundance of microbiota of great diversity was found in the stomach.
Ximo Wang
exaly +3 more sources
Characterization of Gastric Microbiota in Twins
Current Microbiology, 2016Contribution of host genetic backgrounds in the development of gastric microbiota has not been clearly defined. This study was aimed to characterize the biodiversity, structure and composition of gastric microbiota among twins. A total of four pairs of twins and eight unrelated individuals were enrolled in the study.
Quanjiang, Dong +6 more
openaire +2 more sources
Other Helicobacters and gastric microbiota
Helicobacter, 2016AbstractThis article aimed to review the literature from 2015 dealing with gastric and enterohepatic non‐Helicobacter pylori Helicobacter species (NHPH). A summary of the gastric microbiota interactions with H. pylori is also presented. An extensive number of studies were published during the last year and have led to a better understanding of the ...
Chloë, De Witte +4 more
openaire +2 more sources