Results 61 to 70 of about 484,967 (279)

The Spatial Landscape of the Bacterial Community and Bile Acids in the Digestive Tract of Patients With Bile Reflux

Frontiers in Microbiology, 2022
BackgroundBile reflux can lead to inflammation and increased intestinal metaplasia. Since bile acids can influence the gastrointestinal environment, it is possible that bile reflux may alter the gastric microbiota and potentially the oral or gut ...
Ni Yang, Ni Yang, Jun Xu, Jun Xu, Xuemei Wang, Xuemei Wang, Ning Chen, Ning Chen, Lin Su, Lin Su, Yulan Liu, Yulan Liu   +11 more
doaj   +1 more source

Participation of microbiota in the development of gastric cancer

World Journal of Gastroenterology, 2014
There are a large number of bacteria inhabiting the human body, which provide benefits for the health. Alterations of microbiota participate in the pathogenesis of diseases. The gastric microbiota consists of bacteria from seven to eleven phyla, predominantly Proteobacteria, Firmicutes, Bacteroidetes, Actinobacteria and Fusobacteria.
Li-Li, Wang, Xin-Juan, Yu, Shu-Hui, Zhan, Sheng-Jiao, Jia, Zi-Bin, Tian, Quan-Jiang, Dong   +5 more
openaire   +2 more sources

Microbiota–Gastric Cancer Interactions and the Potential Influence of Nutritional Therapies [PDF]

Gastric cancer (GC) is one of the most common causes of cancer deaths, and GC treatments represent a large area of research. Although initially regarded as a sterile organ and unsuitable for microbial communities, the discovery of Helicobacter  ...
Antonio Gasbarrini, Marco Cintoni, Maria Cristina Mele, Emidio Scarpellini, Valeria Maccauro, Pauline Raoul, Emanuele Rinninella, Gianluca Ianiro   +7 more
core   +2 more sources

Human gastric microbiota transplantation recapitulates premalignant lesions in germ-free mice

, 2021
Objective: Gastric cancer (GC) is a leading cause of cancer-related mortality. Although microbes besides Helicobacter pylori may also contribute to gastric carcinogenesis, wild-type germ-free (GF) mouse models investigating the role of human gastric ...
이용찬, 김광휘, 남기택, 김성희, 박준철, Jun Chul Park, Haengdueng Jeong, Yong Chan Lee, Bo Ram Hwang, Sung-Hee Kim, So Dam Lee, Soon-Kyeong Kwon, Yejin Cho, Yeseul Oh, Buhyun Lee, Jihyun F Kim, Kwang H Kim, Jin-Jae Lee, Yusook Chung, Ki Taek Nam, Jaekyung Yoon   +20 more
core   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Change of the duodenal mucosa-associated microbiota is related to intestinal metaplasia

BMC Microbiology, 2019
Background In this study, we aimed to investigate the characteristics of the duodenal mucosal microbiota of patients with intestinal metaplasia (IM) and compare it with those of the gastric mucosal microbiota. Method We collected the duodenal and gastric
Jian Gong, Lixiang Li, Xiuli Zuo, Yanqing Li   +3 more
doaj   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Do we need gastric acid? [PDF]

, 2008
Evidence from comparative anatomy and physiology studies indicates that gastric acid secretion developed during the evolution of vertebrates approximately 350 million years ago.
Lippl, F., Lippl, F, Schiefke, I, Prinz, C., Pohl, D, Rogler, G., Prinz, C, Fox, M, Mönnikes, H, Schiefke, I., Keller, J, Seidler, U, Allescher, H D, Dauer, M, Göke, B., Seidler, U., Keller, J., Fox, M., Göke, B, Pohl, D., Moennikes, H., Dauer, M., Rogler, G, Kandahar Study Group, Fried, M, Allescher, H. D., Pohl, D.;Fox, M.;Fried, M.;Göke, B.;Prinz, C.;Mönnikes, H.;Rogler, G.;Dauer, M.;Keller, J.;Lippl, F.;Schiefke, I.;Seidler, U.;Allescher, H. D., Pohl, D;Fox, M;Fried, M;Göke, B;Prinz, C;Monnikes, H;Rögler, G;Dauer, M;Keller, J;Lippl, F;Schiefke, I;Seidler, U;Allescher, HD, Prinz C, Allescher HD, Mönnikes H, Schiefke I, Rogler G, Fox M, Pohl D, Seidler U, Dauer M, Keller J, Göke B, Lippl F, Fried M   +40 more
core   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Metabolic Interaction of Helicobacter pylori Infection and Gut Microbiota

, 2016
As a barrier, gut commensal microbiota can protect against potential pathogenic microbes in the gastrointestinal tract. Crosstalk between gut microbes and immune cells promotes human intestinal homeostasis. Dysbiosis of gut microbiota has been implicated
Bor-Shyang Sheu, Yao-Jong Yang
core   +1 more source