Results 41 to 50 of about 236 (109)

Pentadecapeptide BPC 157 as Therapy for Inferior Caval Vein Embolization: Recovery of Sodium Laurate-Post-Embolization Syndrome in Rats

Pharmaceuticals, 2023
After inferior caval vein embolization therapy, post-embolization syndrome (sodium laurate 10 mg/kg, 0.1 mL into rat inferior caval vein, assessment at 15, 30, 60 min, prime lung lesions, thromboemboli occluding lung vessels), as a severe occlusion ...
Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Marija Skoro, Katarina Kasnik Kovac, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Sanja Strbe, Marijan Tepes, Katarina Oroz, Slavica Zubcic, Mirjana Stupnisek, Lidija Beketic Oreskovic, Ivana Kavelj, Luka Novosel, Matea Prenc, Sanja Barsic Ostojic, Ivan Dobric, Marko Sever, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Ivica Sjekavica, Sven Seiwerth, Predrag Sikiric   +27 more
doaj   +1 more source

Stable Gastric Pentadecapeptide BPC 157 and Intestinal Anastomoses Therapy in Rats-A Review. [PDF]

Pharmaceuticals (Basel)
By introducing the healing of many distinctive anastomoses by BPC 157 therapy, this review practically deals with the concept of the resection and reconnection of the hollow parts of the gastrointestinal tract as one of the cornerstones of visceral surgery.
Bajramagic S, Sever M, Rasic F, Staresinic M, Skrtic A, Beketic Oreskovic L, Oreskovic I, Strbe S, Loga Zec S, Hrabar J, Coric L, Prenc M, Blagaic V, Brcic K, Boban Blagaic A, Seiwerth S, Sikiric P.   +16 more
europepmc   +4 more sources

In relation to NO‐System, Stable Pentadecapeptide BPC 157 Counteracts Lidocaine‐Induced Adverse Effects in Rats and Depolarisation In Vitro

Emergency Medicine International, Volume 2020, Issue 1, 2020., 2020
Recently, the pentadecapeptide BPC 157‐induced counteraction of bupivacaine cardiotoxicity has been reported. Medication includes (i) lidocaine‐induced local anesthesia via intraplantar application and axillary and spinal (L4‐L5) intrathecal block, (ii) lidocaine‐induced arrhythmias, (iii) convulsions, and (iv) lidocaine‐induced HEK293 cell ...
Marin Lozic, Vasilije Stambolija, Ivan Krezic, Aleksandra Dugandzic, Gordana Zivanovic-Posilovic, Slaven Gojkovic, Josip Kovacevic, Luka Vrdoljak, Ivan Mirkovic, Antonio Kokot, Andreja Petrovic, Katarina Horvat Pavlov, Domagoj Drmic, Jelena Suran, Alenka Boban Blagaic, Sven Seiwerth, Predrag Sikiric, Chak W. Kam   +17 more
wiley   +1 more source

Stable Gastric Pentadecapeptide BPC 157: Prompt Particular Activation of Collateral Pathways

Current Medicinal Chemistry, 2023

Sikirić, Predrag, Gojković, Slaven, Knežević, Mario, Tepeš, Marijan, Štrbe, Sanja, Vukojević, Jakša, Đuzel, Antonija, Kralj, Tamara, Krezić, Ivan, Žižek, Helena, Oroz, Katarina, Vraneš, Hrvoje, Smoday, Ivan Maria, Kalogjera, Luka, Vlainić, Josipa, Kokot, Antonio, Jurjević, Ivana, Boban Blagaić, Alenka, Škrtić, Anita, Seiwert, Sven   +19 more
openaire   +2 more sources

Pentadecapeptide BPC 157, in Clinical Trials as a Therapy for Inflammatory Bowel Disease (PL14736), Is Effective in the Healing of Colocutaneous Fistulas in Rats: Role of the Nitric Oxide-System

Journal of Pharmacological Sciences, 2008
We focused on the therapeutic effect of the stable gastric pentadecapeptide BPC 157 and how its action is related to nitric oxide (NO) in persistent colocutaneous fistula in rats (at 5 cm from anus, colon defect of 5 mm, skin defect of 5 mm); this ...
Robert Klicek, Marko Sever, Bozo Radic, Domagoj Drmic, Ivan Kocman, Ivan Zoricic, Tihomir Vuksic, Mihovil Ivica, Ivan Barisic, Spomenko Ilic, Lidija Berkopic, Hrvoje Vrcic, Luka Brcic, Alenka Boban Blagaic, Marijana Coric, Iva Brcic, Dinko Stancic Rokotov, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +1 more source

Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine. [PDF]

PLoS ONE, 2015
BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker,
Mirjana Stupnisek, Antonio Kokot, Domagoj Drmic, Masa Hrelec Patrlj, Anita Zenko Sever, Danijela Kolenc, Bozo Radic, Jelena Suran, Davor Bojic, Aleksandar Vcev, Sven Seiwerth, Predrag Sikiric   +11 more
doaj   +1 more source

Intragastric Application of Aspirin, Clopidogrel, Cilostazol, and BPC 157 in Rats: Platelet Aggregation and Blood Clot

Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
We suggest that the stable gastric pentadecapeptide BPC 157 may rescue thrombocyte function. We focused on the antithrombotic agent aspirin, clopidogrel, and cilostazol application in rats; arachidonic acid, ADP, collagen, and arachidonic acid/PGE1 platelet aggregation (aggregometry) and blood clot viscoelastic properties (thromboelastometry); and the ...
Sanja Konosic, Mate Petricevic, Visnja Ivancan, Lucija Konosic, Eleonora Goluza, Branimir Krtalic, Domagoj Drmic, Mirjana Stupnisek, Sven Seiwerth, Predrag Sikiric, Aleksandar Kibel   +10 more
wiley   +1 more source

Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy

Current Issues in Molecular Biology, 2022
Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1 min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) appeared after a single intraperitoneal administration of the ...
Darko Perovic, Marija Milavic, Stjepan Dokuzovic, Ivan Krezic, Slaven Gojkovic, Hrvoje Vranes, Igor Bebek, Vide Bilic, Nenad Somun, Ivan Brizic, Ivan Skorak, Klaudija Hriberski, Suncana Sikiric, Eva Lovric, Sanja Strbe, Milovan Kubat, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +19 more
doaj   +1 more source

Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats

World Journal of Gastroenterology, 2004
To investigate the protective effects of gastric pentadecapeptide BPC 157 on acute and chronic gastric ulcers in rats and to compare the results in therapy of human gastric ulcers by different administration methods.Gastric pentadecapeptide BPC 157 was administered (initial single or continuous administration) into rats either intragastrically or ...
Xiao-Chang, Xue, Yong-Jie, Wu, Ming-Tang, Gao, Wen-Guang, Li, Ning, Zhao, Zeng-Lu, Wang, Chun-Jie, Bao, Zhen, Yan, Ying-Qi, Zhang   +8 more
openaire   +2 more sources

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts

Molecules, 2014
BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies.
Chung-Hsun Chang, Wen-Chung Tsai, Ya-Hui Hsu, Jong-Hwei Su Pang   +3 more
doaj   +1 more source