Results 51 to 60 of about 483,352 (126)

Novel Therapeutic Effects in Rat Spinal Cord Injuries: Recovery of the Definitive and Early Spinal Cord Injury by the Administration of Pentadecapeptide BPC 157 Therapy

open access: yesCurrent Issues in Molecular Biology, 2022
Recently, marked therapeutic effects pertaining to the recovery of injured rat spinal cords (1 min compression injury of the sacrocaudal spinal cord (S2-Co1) resulting in tail paralysis) appeared after a single intraperitoneal administration of the ...
Darko Perovic   +19 more
doaj   +1 more source

BPC 157 Therapy and the Permanent Occlusion of the Superior Sagittal Sinus in Rat: Vascular Recruitment

open access: yesBiomedicines, 2021
We show the complex syndrome of the occluded superior sagittal sinus, brain swelling and lesions and multiple peripheral organs lesions in rat. Recovery goes centrally and peripherally, with the stable gastric pentadecapeptide BPC 157, which alleviated ...
Slaven Gojkovic   +18 more
doaj   +1 more source

Pentadecapeptide BPC 157 and Rac 1 inhibitors [PDF]

open access: yes, 2016
UVOD: Rac1 je mali signalizirajući G-protein koji može aktivirati NF-kappaB. Pentadekapeptid BPC 157 smanjuje transkripciju Vcam-1 u NF-kappaB signalnom putu kao i neki NF-kappaB inhibitori te suprimira da ERK inducira Vcam-1 preko NF-kappaB aktivacije ...
Vidović, Tinka
core   +1 more source

Prolonged Esophagitis After Primary Dysfunction of the Pyloric Sphincter in the Rat and Therapeutic Potential of the Gastric Pentadecapeptide BPC 157

open access: yesJournal of Pharmacological Sciences, 2007
Seven or fourteen days or twelve months after suturing one tube into the pyloric sphincter (removed by peristalsis by the seventh day), rats exhibit prolonged esophagitis with a constantly lowered pressure not only in the pyloric, but also in the lower ...
Ivan Dobric   +21 more
doaj   +1 more source

An Experimental Model of Prolonged Esophagitis With Sphincter Failure in the Rat and the Therapeutic Potential of Gastric Pentadecapeptide BPC 157

open access: yesJournal of Pharmacological Sciences, 2006
We report a simple novel rat model that combines prolonged esophagitis and parallel sphincters failure. The anti-ulcer gastric pentadecapeptide BPC 157, which was found to be stable in gastric juice, and is being evaluated in inflammatory bowel disease ...
Igor Petrovic   +17 more
doaj   +1 more source

PENTADECAPEPTIDE BPC 157: PANACEA OR OVERHYPED PEPTIDE? [PDF]

open access: yes
Interest in Pentadecapeptide BPC 157, an oligopeptide originally derived from human gastric juice, has grown substantially among members of the fitness community in the past few years due to its wide range of purported and previously reported effects on ...
Giandonato, Joseph A., Tringali, Victor
core   +1 more source

Fourier Transform Infrared Spectroscopy Reveals Molecular Changes in Blood Vessels of Rats Treated with Pentadecapeptide BPC 157

open access: yesBiomedicines, 2022
Recently, it was found that when confronted with major vessel occlusion and vascular failure, stable gastric pentadecapeptide BPC 157 therapy might rapidly functionally improve minor vessels to take over the function of disabled major vessels, reorganize
Ozren Gamulin   +18 more
doaj   +1 more source

ISOSORBIDE-5-MONONITRATE INDUCED PERIPHERAL AND CENTRAL VASCULAR DYSFUNCTION IN RATS AND TRETMENT WITH STABLE GASTRIC PENTADECAPEPTIDE BPC 157 [PDF]

open access: yes, 2023
Introduction: Although the understanding of migraine pathophysiology is incomplete, it is now well accepted that this neurovascular syndrome is mainly due to cranial vasodilation.
Kalogjera, Luka   +2 more
core   +1 more source

Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review

open access: yesPharmaceuticals
BPC 157, known as the “Body Protection Compound”, is a pentadecapeptide isolated from human gastric juice that demonstrated its pleiotropic beneficial effects in various preclinical models mimicking medical conditions, such as tissue injury, inflammatory
Michalina Józwiak   +3 more
doaj   +1 more source

Stable Gastric Pentadecapeptide BPC 157 Antagonized Local Anesthetic Effect of Lidocaine [PDF]

open access: yes, 2019
We documented that stable gastric pentadecapeptide BPC 157 counteracts convulsions induced by concomitant application of atypical neuroleptic, SSRI and NSAID, risperidone, citalopram and metamizole in rats.
Dretar, Vilim   +9 more
core   +1 more source

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