Results 51 to 60 of about 236 (109)

BPC 157 Therapy and the Permanent Occlusion of the Superior Sagittal Sinus in Rat: Vascular Recruitment

Biomedicines, 2021
We show the complex syndrome of the occluded superior sagittal sinus, brain swelling and lesions and multiple peripheral organs lesions in rat. Recovery goes centrally and peripherally, with the stable gastric pentadecapeptide BPC 157, which alleviated ...
Slaven Gojkovic, Ivan Krezic, Hrvoje Vranes, Helena Zizek, Domagoj Drmic, Katarina Horvat Pavlov, Andrea Petrovic, Lovorka Batelja Vuletic, Marija Milavic, Suncana Sikiric, Irma Stilinovic, Mariam Samara, Mario Knezevic, Ivan Barisic, Ivica Sjekavica, Eva Lovric, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +1 more source

An Experimental Model of Prolonged Esophagitis With Sphincter Failure in the Rat and the Therapeutic Potential of Gastric Pentadecapeptide BPC 157

Journal of Pharmacological Sciences, 2006
We report a simple novel rat model that combines prolonged esophagitis and parallel sphincters failure. The anti-ulcer gastric pentadecapeptide BPC 157, which was found to be stable in gastric juice, and is being evaluated in inflammatory bowel disease ...
Igor Petrovic, Ivan Dobric, Petar Drvis, Drazen Shejbal, Luka Brcic, Alenka Boban Blagaic, Lovorka Batelja, Neven Kokic, Ante Tonkic, Stjepan Mise, Tomislav Baotic, Mario Staresinic, Bozo Radic, Ana Jakir, Tihomir Vuksic, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +17 more
doaj   +1 more source

Prolonged Esophagitis After Primary Dysfunction of the Pyloric Sphincter in the Rat and Therapeutic Potential of the Gastric Pentadecapeptide BPC 157

Journal of Pharmacological Sciences, 2007
Seven or fourteen days or twelve months after suturing one tube into the pyloric sphincter (removed by peristalsis by the seventh day), rats exhibit prolonged esophagitis with a constantly lowered pressure not only in the pyloric, but also in the lower ...
Ivan Dobric, Petar Drvis, Igor Petrovic, Drazen Shejbal, Luka Brcic, Alenka Boban Blagaic, Lovorka Batelja, Marko Sever, Neven Kokic, Ante Tonkic, Ivan Zoricic, Sandro Mise, Mario Staresinic, Bozo Radic, Ana Jakir, Jaksa Babel, Spomenko Ilic, Tihomir Vuksic, Ivan Jelic, Tomislav Anic, Sven Seiwerth, Predrag Sikiric   +21 more
doaj   +1 more source

Fourier Transform Infrared Spectroscopy Reveals Molecular Changes in Blood Vessels of Rats Treated with Pentadecapeptide BPC 157

Biomedicines, 2022
Recently, it was found that when confronted with major vessel occlusion and vascular failure, stable gastric pentadecapeptide BPC 157 therapy might rapidly functionally improve minor vessels to take over the function of disabled major vessels, reorganize
Ozren Gamulin, Katarina Oroz, Luka Coric, Maria Krajacic, Marko Skrabic, Vilim Dretar, Sanja Strbe, Jasminka Talapko, Martina Juzbasic, Ivan Krezic, Marin Lozic, Vasilije Stambolija, Helena Zizek, Ivana Jurca, Ivana Jurjevic, Alenka Boban Blagaic, Anita Skrtic, Sven Seiwerth, Predrag Sikiric   +18 more
doaj   +1 more source

Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review

Pharmaceuticals
BPC 157, known as the “Body Protection Compound”, is a pentadecapeptide isolated from human gastric juice that demonstrated its pleiotropic beneficial effects in various preclinical models mimicking medical conditions, such as tissue injury, inflammatory
Michalina Józwiak, Marta Bauer, Wojciech Kamysz, Patrycja Kleczkowska   +3 more
doaj   +1 more source

Stable gastric pentadecapeptide BPC 157 and insulin induced gastric lesions in rats.

Journal of physiology and pharmacology, 2009
The stable gastric pentadecapeptid BPC 157 (GEPPGKPADDAGLV, M.W. 1419) is a small anti- ulcer peptide efficient in inflammatory bowed disease trials (PL 14736) and various wound tretment, no toxiicity reported. Interestingly, it may have therapeutic effect on acute panckeatitis and act protzectively on endothelium, affects many central disturbances and
Ilić, S, Mester, M, Filipović, M, Sever, M, Klicek, R, Barisic, I, Zoričić, Z, Bilić, V, Berkopić, L, Brcic, L, Brcic, I, Kolenc, D, Seiwerth, S, Sikiric P   +13 more
openaire   +3 more sources

Unilateral Adrenalectomy, and the Stable Pentadecapeptide BPC 157 as Therapy in Rats—A Cytoprotection Approach

Pharmaceuticals
Background. This rat study reveals a new point: the considerable impact of unilateral adrenalectomy, severe vascular and multiorgan failure, occlusion/occlusion-like syndrome, and the stable gastric pentadecapeptide BPC 157 therapy.
Ivan Maria Smoday, Vlasta Vukovic, Katarina Oroz, Hrvoje Vranes, Luka Kalogjera, Ozren Gamulin, Josipa Vlainic, Marija Milavic, Suncana Sikiric, Nora Nikolac Gabaj, Domagoj Marijancevic, Antun Koprivanac, Laura Tomic, Sanja Strbe, Ivan Barisic, Lidija Beketic Oreskovic, Mario Kordic, Ante Tvrdeic, Sven Seiwerth, Predrag Sikiric, Alenka Boban Blagaic, Anita Skrtic   +21 more
doaj   +1 more source

Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats. [PDF]

Pharmaceuticals (Basel), 2023
Tepes M, Krezic I, Vranes H, Smoday IM, Kalogjera L, Zizek H, Vukovic V, Oroz K, Kovac KK, Madzar Z, Rakic M, Miskic B, Sikiric S, Barisic I, Strbe S, Antunovic M, Novosel L, Kavelj I, Vlainic J, Dobric I, Staresinic M, Skrtic A, Seiwerth S, Blagaic AB, Sikiric P.   +24 more
europepmc   +1 more source

Stomach perforation-induced general occlusion/occlusion-like syndrome and stable gastric pentadecapeptide BPC 157 therapy effect. [PDF]

World J Gastroenterol, 2023
Kalogjera L, Krezic I, Smoday IM, Vranes H, Zizek H, Yago H, Oroz K, Vukovic V, Kavelj I, Novosel L, Zubcic S, Barisic I, Beketic Oreskovic L, Strbe S, Sever M, Sjekavica I, Skrtic A, Boban Blagaic A, Seiwerth S, Sikiric P.   +19 more
europepmc   +1 more source

Corrigendum: Stable Gastric Pentadecapeptide BPC 157 Therapy for Primary Abdominal Compartment Syndrome in Rats. [PDF]

Front Pharmacol, 2021
Tepes M, Gojkovic S, Krezic I, Zizek H, Vranes H, Madzar Z, Santak G, Batelja L, Milavic M, Sikiric S, Kocman I, Simonji K, Samara M, Knezevic M, Barisic I, Lovric E, Strbe S, Kokot A, Sjekavica I, Kolak T, Skrtic A, Seiwerth S, Blagaic AB, Sikiric P.   +23 more
europepmc   +1 more source