Spinal neurons that contain gastrin-releasing peptide seldom express Fos or phosphorylate extracellular signal-regulated kinases in response to intradermal chloroquine [PDF]
, 2016 Background: Gastrin-releasing peptide (GRP) is thought to play a role in the itch evoked by intradermal injection of chloroquine. Although some early studies suggested that GRP was expressed in pruriceptive primary afferents, it is now thought that GRP ...
Bell, Andrew M. +3 more
core +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy +16 more
wiley +1 more source
Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]
, 2017 Background: Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Blandamura, Stella +6 more
core +2 more sources
Equine Veterinary Education, EarlyView.Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley +1 more source
Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review
International Journal of Dermatology, EarlyView.ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska +8 more
wiley +1 more source
Enpostil Lowers Elevated Serum Gastrin Concentrations in Patients with Pernicious Anemia
Canadian Journal of Gastroenterology, 1991 A double-blind, randomized, crossover, placebo controlled study of Latin square design was conducted to determine the gastrin-lowering effects of a synthetic orally administered prostaglandin, enprostil, in fasted and fed patients with hypergastrinemia ...
P Kirdeikis +5 more
doaj +1 more source
Successful Chemotherapy Induction Following Management of Obstructive Jaundice and Femoral Pathological Fracture in Extensive-Stage Small Cell Lung Cancer: A Case Report. [PDF]
Respirol Case RepA 76‐year‐old man with extensive‐stage SCLC presented with obstructive jaundice from pancreatic metastasis and a pathological femoral fracture. Multidisciplinary management, including biliary stenting and hemiarthroplasty, improved his performance status, enabling systemic chemotherapy.
Hashimoto N +9 more
europepmc +2 more sources
Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels [PDF]
, 1997 There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is widely recognized as the dominant pacemaker of the circadian system, we have ...
Almeida, OFX +5 more
core +1 more source
The exposomal imprint on rosacea: More than skin deep
Journal of the European Academy of Dermatology and Venereology, EarlyView.Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki +3 more
wiley +1 more source
Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]
, 2002 Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core +2 more sources