Non-Steroidal Anti-Inflammatory Drugs in the Carcinogenesisof the Gastrointestinal Tract [PDF]
, 2010 It is estimated that underlying infections and inflammatory responses are linked to 15–20% of all deaths from cancer worldwide. Inflammation is a physiologic process in response to tissue damage resulting from microbial pathogen infection, chemical ...
COMPARE, DEBORA +2 more
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Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: Avaliar as concentrações pré e pós-operatória da gastrina sérica, hormônio fundamental na produção do ácido clorídrico gástrico, correlacionando-as com as complicações cloridropépticas pós-cirúrgicas, em pacientes submetidos à gastroplastia ...
Edmundo Anderi Jr +3 more
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Exploring the application value of pro‐gastrin‐releasing peptide in the clinical diagnosis and surgical treatment of medullary thyroid carcinoma [PDF]
, 2023 Qiang Miao +4 more
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Acute effects of N-terminal progastrin fragments on gastric acid secretion in man [PDF]
, 2017 We previously identified an N‐terminal fragment of progastrin in human antrum and plasma, where it circulates in high concentrations. In this study, we examined the effects of N‐terminal progastrin fragments on gastric acid secretion by infusion in ...
Goetze, Jens P +2 more
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Helicobacter pylori infection: New pathogenetic and clinical aspects [PDF]
, 2014 Helicobacter pylori (H. pylori) infects more than half of the world’s human population, but only 1% to 3% of infected people consequently develop gastric adenocarcinomas. The clinical outcome of the infection is determined by host genetic predisposition,
Hagymási, Krisztina, Tulassay, Zsolt
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Glycine-extended gastrin promotes the growth of lung cancer [PDF]
, 2004 The less processed forms of gastrin have recently been shown to act as trophic factors for both normal and malignant colonic cells. Although incompletely processed forms of gastrin such as glycine-extended gastrin and progastrin are also expressed in ...
Cui, Guanglin +8 more
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Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [111In-DOTA]MG11 [PDF]
, 2016 Background: We have recently shown that treatment of mice with the neutral endopeptidase (NEP) inhibitor phosphoramidon (PA) improves the bioavailability and tumor uptake of biodegradable radiopeptides.
Jong, M. (Marion) de +6 more
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Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans [PDF]
, 2010 Background & Aims Trefoil factors (TFFs) regulate mucosal repair and suppress tumor formation in the stomach. Tff1 deficiency results in gastric cancer, whereas Tff2 deficiency increases gastric inflammation.
Fox, James G. +10 more
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Targeting the Gastrin-Releasing Peptide Receptor (GRP-R) in Cancer Therapy: Development of Bombesin-Based Peptide–Drug Conjugates [PDF]
, 2023 Jacopo Gomena +9 more
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