Results 31 to 40 of about 35,918 (226)
Research advancements and evaluation of multifactor‐induced murine models for gastric cancer
Animal Models and Experimental Medicine, EarlyView.Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang +5 more
wiley +1 more source
Similar acid stimulatory potencies of synthetic human big and little gastrins in man.
Journal of Clinical Investigation, 1984 A newly synthesized human big gastrin (G34) that was prepared according to the revised structure and that contained less than 3% oxidized methionine residues was compared with synthetic human little gastrin (G17) for acid-stimulating activity and ...
V. Eysselein +4 more
semanticscholar +1 more source
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
ChemMedChem, Accepted Article.The cannabinoid receptor type 2 (CB2R) is overexpressed under pathological conditions. PET is a suitable non‐invasive imaging technique for diagnosing disease states, but requires a radiotracer that binds to CB2R with high affinity and selectivity. Currently, there is no suitable candidate routinely used in the clinics.
Lea Ueberham +4 more
wiley +1 more source
Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine
European Journal of Organic Chemistry, EarlyView.Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng +2 more
wiley +1 more source
Effects of myoinhibitory peptides on food intake in the German cockroach [PDF]
, 2017 Insect myoinhibitory peptides were discovered through their inhibitory activity on visceral muscle contraction. The present study tests the antimyotropic gut properties of three galanin-related myoinhibitory peptides (Mas-MIP II: GWQDLNSAW-NH2; Grb-AST ...
Aguilar, Ruth +2 more
core +1 more source
Divergent roles for ferric ions in the biological activity of amidated and non-amidated gastrins.
Journal of Endocrinology, 2004 Amidated forms of the peptide hormone gastrin act via the cholecystokinin-2 receptor to stimulate gastric acid secretion, whereas non-amidated forms stimulate colonic mucosal proliferation via a novel, as yet uncharacterised, receptor.
Julie Pannequin +4 more
semanticscholar +1 more source
The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan +5 more
wiley +1 more source
Identification of gastrin molecular variants in gastrinoma syndrome [PDF]
, 1987 The molecular species of gastrin in the circulation and in tumor extracts were studied in two groups of patients: (1) with benign gastrinoma and (2) with gastrinoma with liver metastases. Radioimmunoassays (RIAs) and immunoaffinity chromatography for the
Kothary, Piyush C. +2 more
core +1 more source