Results 51 to 60 of about 35,918 (226)

Controversies in NEN: An ENETS position statement on the endoscopic management of localised gastric, duodenal and rectal neuroendocrine neoplasms

Journal of Neuroendocrinology, EarlyView.
Abstract Gastric, duodenal and rectal neuroendocrine tumours (NETs) are increasingly detected due to advances in endoscopic imaging. While international guidelines provide criteria for endoscopic management, several aspects remain controversial due to limited high‐quality evidence.
Francesco Panzuto, Dermot O'Toole, Günter Klöppel, Ulrich Peter Knigge, Günter Josef Krejs, Marina Tsoli, Marco Volante, Tu Vinh Luong   +7 more
wiley   +1 more source

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

Neurogastroenterology &Motility, EarlyView.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi, Rudolf Bauer, Thomas Efferth, Mohamed T. Khayyal, Michael Schemann, Gudrun Ulrich‐Merzenich, Christine Feinle‐Bisset   +6 more
wiley   +1 more source

Therapeutic Role of Probiotics for the Treatment of Dyspepsia: A Review of the Literature

Neurogastroenterology &Motility, EarlyView.
Recent studies suggest that microbiota imbalance plays a significant role in the development of functional dyspepsia (FD). Specifically, patients with FD have shown increased levels of Streptococcus and decreased levels of Prevotella, Veillonella, and Actinomyces.
Giovanni Marasco, Miriam Fiocca, Cesare Cremon, Luigi Colecchia, Marcello Maida, Elton Dajti, Maria Raffaella Barbaro, Vincenzo Stanghellini, Giovanni Barbara   +8 more
wiley   +1 more source

Identification and cardiotropic actions of sulfakinin peptides in the American lobster Homarus americanus [PDF]

, 2007
In arthropods, a group of peptides possessing a -Y(SO3H)GHM/ LRFamide carboxy-terminal motif have been collectively termed the sulfakinins. Sulfakinin isoforms have been identified from numerous insect species. In contrast, members of this peptide family
Brennan, Henry R., Christie, Andrew E., Dickinson, Patsy S., Goiney, Christopher C., Li, Lingjun, Rus, Szymon, Smith, Christine M., Stevens, Jake S., Towle, David W.   +8 more
core   +1 more source

Single‐cell transcriptomics of human organoid‐derived enteroendocrine cell populations from the small intestine

The Journal of Physiology, EarlyView.
Abstract figure legend Human intestinal organoids were genetically modified to express a fluorescent protein in enteroendocrine cells (EECs), which were then separated by flow cytometry and analysed by single‐cell RNA sequencing. High numbers of human EECs were thereby available for cluster analysis and differential gene expression, revealing ...
Christopher A. Smith, Van B. Lu, Rula Bany Bakar, Emily Miedzybrodzka, Adam Davison, Deborah Goldspink, Frank Reimann, Fiona M. Gribble   +7 more
wiley   +1 more source

Food-pharma convergence in medical nutrition [PDF]

, 2013
At present, industries within the health and life science sector are moving towards one another resulting in new industries such as the medical nutrition industry.
Claassen, H.J.H.M. (Eric), Commandeur, H.R. (Harry), Pronker, E.S. (Esther), Ramezanpour, B. (Bahar), Weenen, T.C. (Tamar)   +4 more
core   +1 more source

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

Cell cycle dependent expression of the CCK2 receptor by gastrointestinal myofibroblasts: putative role in determining cell migration. [PDF]

, 2017
The well-known action of the gastric hormone gastrin in stimulating gastric acid secretion is mediated by activation of cholecystokinin-2 receptors (CCK2R).
Dockray, Graham J, Dodd, Steven, Hegyi, Peter, Kumar, Jothi Dinesh, Simpson, Alec WM, Varga, Akos, Varro, Andrea   +6 more
core   +1 more source

Antitumor efficacy of intermittent low‐dose erlotinib plus sulindac via MHC upregulation and remodeling of the immune cell niche

International Journal of Cancer, Volume 157, Issue 2, Page 355-370, 15 July 2025.
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi, Jorge E. Tovar Perez, Sabeeta Kapoor, Ahmed Muhsin, Wan Mohaiza Dashwood, Yunus Demirhan, Melek Demirhan, Alessandro Shapiro, Altaf Mohammed, Shizuko Sei, Jacklyn Thompson, Mahira Zaheer, Krishna M. Sinha, Powel H. Brown, Michelle I. Savage, Eduardo Vilar, Praveen Rajendran, Roderick H. Dashwood   +17 more
wiley   +1 more source

Identification of a tachykinin-related peptide with orexigenic properties in the German cockroach [PDF]

, 2017
A number of evidences suggest that tachykinin-related peptides (TRPs) of insects can stimulate food consumption after being released from the midgut to the hemolymph.
Andreu, David, Bellés, Xavier, Chiva, Cristina, Maestro, José L., Pascual Duran, Nuria   +4 more
core   +1 more source