Results 1 to 10 of about 159,192 (308)

Experimental study and clinical significance of the impact of gastrointestinal motility disorders on hepatic blood perfusion [PDF]

Frontiers in Medicine
IntroductionThe gastrointestinal tract and liver maintain intricate hemodynamic relationships through the portal venous system. While gastrointestinal motility disorders are known to affect digestive function, their impact on hepatic blood perfusion ...
Jin Tonghui, Liu Tiejun, Liu Chaoyue, Wang Han, Wang Han   +4 more
doaj   +2 more sources

The mechanisms of nerve injury caused by viral infection in the occurrence of gastrointestinal motility disorder-related diseases [PDF]

Virology Journal, 2023
Gastrointestinal motility refers to the peristalsis and contractility of gastrointestinal muscles, including the force and frequency of gastrointestinal muscle contraction.
Yaqian Li, Qiuyu Chen, Liwei Wang, Xin Chen, Bangmao Wang, Weilong Zhong   +5 more
doaj   +2 more sources

Therapeutic role of Wuda granule in gastrointestinal motility disorder through promoting gastrointestinal motility and decreasing inflammatory level [PDF]

Frontiers in Pharmacology, 2023
Introduction: Previous studies indicated that Wuda Granule (WDG) has been applied in the treatment of gastrointestinal motility disorder (GMD), but the effect and underlying mechanisms is yet to be elucidated.
Zhi Jiang, Qiuping Zou, Qiuping Zou, Qicheng Chen, Junhong Zhang, Hailin Tang, Jingbao Chen, You Qin, Liming Yang, Zhiqiang Chen, Lixing Cao   +10 more
doaj   +2 more sources

Circadian rhythm disruption modulates enteric neural precursor cells differentiation leading to gastrointestinal motility dysfunction via the NR1D1/NF-κB axis [PDF]

Journal of Translational Medicine
Objectives Circadian rhythm disruption (CRD) is implicated with numerous gastrointestinal motility diseases, with the enteric nervous system (ENS) taking main responsibility for the coordination of gastrointestinal motility.
Yurui Zhang, Shizhao Xu, Mengke Fan, Hailing Yao, Chen Jiang, Qi He, Huiying Shi, Rong Lin   +7 more
doaj   +2 more sources

A Systematic and a Scoping Review on the Psychometrics and Clinical Utility of the Volume-Viscosity Swallow Test (V-VST) in the Clinical Screening and Assessment of Oropharyngeal Dysphagia

Foods, 2021
(1) Background: The volume-viscosity swallow test (V-VST) is a clinical tool for screening and diagnosis of oropharyngeal dysphagia (OD). Our aims were to examine the clinical utility of the V-VST against videofluoroscopy (VFS) or fiberoptic endoscopic ...
Stephanie A. Riera, Sergio Marin, Mateu Serra-Prat, Noemí Tomsen, Viridiana Arreola, Omar Ortega, Margaret Walshe, Pere Clavé   +7 more
doaj   +1 more source

Transmembrane Protein 100 Inhibits the Progression of Colorectal Cancer by Promoting the Ubiquitin/Proteasome Degradation of HIF-1α

Frontiers in Oncology, 2022
Transmembrane protein 100 (TMEM100) is involved in embryonic cardiovascular system development. However, the biological role of TMEM100 in human cancers, particularly colorectal cancer (CRC), is unclear.
Ying Zheng, Yitong Zhao, Jiong Jiang, Baicang Zou, Lei Dong   +4 more
doaj   +1 more source

CCL13 and human diseases

Frontiers in Immunology, 2023
CCL13/MCP-4 belongs to the CC chemokine family, which induces chemotaxis in many immune cells. Despite extensive research into its function in numerous disorders, a thorough analysis of CCL13 is not yet accessible.
Laifu Li, Laifu Li, Fei Dai, Fei Dai, Lianli Wang, Lianli Wang, Yating Sun, Yating Sun, Lin Mei, Lin Mei, Yan Ran, Yan Ran, Fangchen Ye, Fangchen Ye   +13 more
doaj   +1 more source

The excitatory effect of hydrogen sulfide on rat colonic muscle contraction and the underlying mechanism

Journal of Pharmacological Sciences, 2022
H2S is a well-known relaxant regulator in muscle contraction but little attention has been paid to its excitatory effect on colonic motility. To investigate the excitation of H2S on rat colonic contraction and the underlying mechanism, the muscle ...
Xiaojing Quan, Wei Chen, Bin Qin, Jinhai Wang, Hesheng Luo, Fei Dai   +5 more
doaj   +1 more source

CARM1 promotes gastric cancer progression by regulating TFE3 mediated autophagy enhancement through the cytoplasmic AMPK-mTOR and nuclear AMPK-CARM1-TFE3 signaling pathways

Cancer Cell International, 2022
Background The role of CARM1 in tumors is inconsistent. It acts as an oncogene in most cancers but it inhibits the progression of liver and pancreatic cancers.
Suzhen Yang, Jing Zhang, Di Chen, Jiayi Cao, Ying Zheng, Yuying Han, Yirong Jin, Shuhui Wang, Ting Wang, Lin Ma, Tingting Luo, Yan Wang, Wen Qin, Lei Dong   +13 more
doaj   +1 more source

α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism. [PDF]

, 2016
Coordinated gastrointestinal smooth muscle contraction is critical for proper nutrient absorption and is altered in a number of medical disorders. In this work, we demonstrate a critical role for the RGD-binding integrin α8β1 in promoting nutrient ...
Atabai, Kamran, Azary, Saeedeh, Ha, Arnold, Hart, Daniel, Khalifeh-Soltani, Amin, McCarthy, Donald A, McKleroy, William, Podolsky, Michael J, Sakuma, Stephen, Stahl, Andreas, Tharp, Kevin M, Wu, Nanyan, Yokosaki, Yasuyuki   +12 more
core   +2 more sources