Results 81 to 90 of about 1,620,741 (300)

Gastrointestinal Stromal Tumor of the Tongue

Philippine Journal of Otolaryngology Head and Neck Surgery, 2013
Objective: To report a case of a gastrointestinal stromal tumor presenting as a recurrent tongue mass Methods: Study Design: Case Report Setting: Tertiary Public Hospital Participant: One patient Results: A 40-year-old Filipino soldier ...
Andrie Jeremy Formanez, Grace Naomi B. Galvan-Bravo   +1 more
doaj   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Anti-Tumor Effects of TRAIL-Expressing Mesenchymal Stromal Cells in a Mouse Xenograft Model of Human Mesothelioma [PDF]

, 2015
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment which contributes to tumor initiation, development, severity, and propagation. We reasoned that
Sage, E, Janes, SM
core  

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Large gastrointestinal stromal tumor size does not imply early recurrence

, 2010
Mohamed Abdel-GhaffarConsultant of Surgery, Sadat General Hospital, First zone, Madinet Al Sadat, Menoufia, EgyptAbstract: A 28-year-old female presented with a huge intra-abdominal mass. Initially a mesenteric mass was diagnosed, but her tumor was found
Mohamed Abdel-Ghaffar
core  

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

British Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said, Robert B. de Mooij, Dian Jiao, Reitze J. Ovelgonne, Rami Biram, Juan Delgado‐SanMartin, Alexander M. K. Rothman, Sofia S. Villar, Andreas A. Roussakis, Jurjan Aman, Ron A. A. Mathôt, Eleonora L. Swart, Martin R. Wilkins, Imke H. Bartelink   +13 more
wiley   +1 more source

Gastrointestinal stromal tumor mesenchymal neoplasms: the offspring that choose the wrong path

, 2013
Nikolaos Machairiotis,1 Ioanna Kougioumtzi,1 Paul Zarogoulidis,2 Aikaterini Stylianaki,1 Konstantinos Tsimogiannis,3 Nikolaos Katsikogiannis11Surgery Department (National Health System), University General Hospital of Alexandroupolis, Alexandroupolis ...
Tsimogiannis K, Katsikogiannis N, Stylianaki A, Machairiotis N, Kougioumtzi I, Zarogoulidis P   +5 more
core  

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Deteksi Dini Gastrointestinal Stromal Tumor

Indonesian Journal of Cancer, 2008
Gastro Intestinal Stromal Tumor (GIST) merupakan keganasan yang berasal dari jaringan mesenkhim dan dapat ditemukan diseluruh jaringan mesenkhim. Istilah gastrointestinal dipakai karena keganasan ini mula-mula aan terbanyak (dua pertiga tumor stromal ...
Dukut Respati Kastomo
doaj   +1 more source

Gastrointestinal Stromal Tumor [PDF]

Mayo Clinic Proceedings, 2019
Ruifeng, Guo, Lori A, Erickson
openaire   +2 more sources