Results 71 to 80 of about 1,620,741 (300)

Proteomic Profiling of Nodal T‐Follicular Helper Cell Lymphoma Reveals Distinct Biological Signatures and Improves Prognostic Stratification Beyond the IPI

American Journal of Hematology, EarlyView.
ABSTRACT Nodal T‐follicular helper cell lymphoma (nTFHL), most commonly of angioimmunoblastic type, exhibits heterogeneous clinical outcomes that are not fully explained by current clinical and biological variables. While genetic alterations have been extensively investigated, its proteomic landscape remains largely unexplored.
David Beauvais, Yanis Zirem, Tristan Cardon, Soulaimane Aboulouard, Romain Dubois, Isabelle Fournier, Franck Morschhauser, Michel Salzet, Ibrahim Yakoub‐Agha, Marie Duhamel   +9 more
wiley   +1 more source

Case report and literature review: patient with gastroduodenal intussusception due to the gastrointestinal stromal tumor of the lesser curvature of the gastric body

BMC Surgery, 2019
Background Intussusception in adult patient is rare. Gastroduodenal intussusception due to the gastrointestinal stromal tumors is infrequently described in the literature.
Mihajlo Đokić, Jerica Novak, Miha Petrič, Branislava Ranković, Miha Štabuc, Blaž Trotovšek   +5 more
doaj   +1 more source

Gastrointestinal stromal tumor – An overview

Indian Journal of Medical and Paediatric Oncology, 2020
Gastrointestinal stromal tumors (GISTs) are rare tumors but are most common mesenchymal tumors of the digestive tract. They are commonly seen in the stomach (60%) and small intestine (30%). GISTs are likely derived from the interstitial cells of Cajal or
Anant Ramaswamy, Vikram Chaudhari, Prabhat Bhargava, Manish Bhandare, Rajiv Kumar, Shailesh V Shrikhande, Vikas Ostwal   +6 more
doaj   +1 more source

Nasal Tuft Cell Markers Are Predictive of Overall Survival in Sinonasal Neuroendocrine and Sinonasal Undifferentiated Carcinomas

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are rare aggressive malignancies with no established prognostic markers. Because features of POU2F3+ small cell lung carcinomas have been identified in both tumors, we evaluated immunostaining for POU2F3, a tuft cell transcription factor, and ...
Nikolina Dioufa, Ricardo V. Bruneto, Jennifer E. Douglas, Nithin D. Adappa, James N. Palmer, Noam A. Cohen, Michael A. Kohanski   +6 more
wiley   +1 more source

Dual‐Function Cosubstrates Enable Threonine Dehydrogenase‐Driven Chemoenzymatic Pyrrole Synthesis

Angewandte Chemie International Edition, EarlyView.
Classical Knorr chemistry meets contemporary biocatalysis. Threonine dehydrogenase generates aminoacetone from l‐threonine, which is directly intercepted in a chemoenzymatic Knorr pyrrole synthesis. A dual‐function β‐dicarbonyl substrate serves as both pyrrole precursor and hydride acceptor for integrated NAD+ recycling, affording substituted pyrroles ...
Valentina Jurkaš, Fabian M. Kulier, Jorge González‐Rodríguez, Carlotta Chiesa, Peter Both, Peter Šiška, Fabio Parmeggiani, Florian Rudroff, Margit Winkler   +8 more
wiley   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

En bloc corpectomy for late gastrointestinal stromal tumor metastasis: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background Spinal metastases of gastrointestinal stromal tumors are rare; however, the incidence has been increasing since the introduction of tyrosine kinase inhibitors, which have improved overall survival.
Takaki Shimizu, Hideki Murakami, Apiruk Sangsin, Satoru Demura, Satoshi Kato, Kazuya Shinmura, Noriaki Yokogawa, Norihiro Oku, Ryo Kitagawa, Hiroyuki Tsuchiya   +9 more
doaj   +1 more source

A Case of Massive Bleeding from Jejunal Stromal Tumor Diagnosed by Intraoperative Enteroscopy -A Case of Jejunal Stromal Tumor Bleeding- [PDF]

, 2003
Gastrointestinal stromal tumors (GISTs) are uncommon tumors that originate from primitive mesenchymal cells. Because GISTs develop throughout the gastrointestinal tract, they present variable heterogenous clinical manifestations such as gastrointestinal ...
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Ruptured Small Intestinal Stromal Tumor Causing Concurrent Gastrointestinal and Intra-Abdominal Hemorrhage: A Case Report [PDF]

Gastrointestinal stromal tumors (GISTs) originate from mesenchymal cells throughout the gastrointestinal tract. A common symptom is gastrointestinal hemorrhage; intra-abdominal hemorrhage is relatively rare.
Tokuyasu, Naruo, 4296, Matsunaga, Tomoyuki, Sakamoto, Teruhisa, キハラ, キョウイチ, Sugesawa, Ken, フジワラ, ヨシユキ, Honjo, Soichiro, ホンジョウ, ソウイチロウ, Fujiwara, Yoshiyuki, Hasegawa, Toshimichi, 3118, 100000247, Tanio, Akimitsu, マツナガ, トモユキ, Tada, Yoichiro, 多田, 陽一郎, 山本, 学, 100000393, 高野, 周一, 徳安, 成郎, トクヤス, ナルオ, 3600, 松永, 知之, Kihara, Kyoichi, Sawata, Shohei, Hara, Kazushi, Takano, Shuichi, 40314330, 377, 16739, 2048, 100001755, 16734, 100001316, 16733, 16738, 16737, 16736, Yamamoto, Manabu, 16735, サカモト, テルヒサ, タダ, ヨウイイチロウ, 16741, 16740, 本城, 総一郎, 藤原, 義之, 780, 坂本, 照尚, 100000374, Ueshima, Chihiro, 3905, 100001149, ヤマモト, マナブ, 16742, 100000935, タカノ, シュウイチ   +56 more
core   +1 more source