Results 241 to 250 of about 87,116 (304)

Making sense of TILs: recommendations for morphological assessment of tumour‐infiltrating lymphocytes in gastro‐oesophageal carcinoma

open access: yesHistopathology, Volume 88, Issue 6, Page 1126-1141, May 2026.
This review examines the role of tumour‐infiltrating lymphocytes (TILs) in gastro‐oesophageal carcinoma (GEC), focusing on their composition, clinical relevance and therapeutic utility. It proposes a framework for standardised evaluation and reporting of TILs, addressing GEC‐specific pathology challenges to support the widespread use and validation of ...
Ylva A Weeda   +38 more
wiley   +1 more source

Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G.   +5 more
wiley   +1 more source

The Prognostic and Biological Value of PGF‐Based H&E Pathomics in Hepatocellular Carcinoma

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Purpose Placental growth factor (PGF) is associated with the progression of hepatocellular carcinoma (HCC), but current research on this relationship remains limited. This study aims to establish a pathomics model for predicting PGF expression levels in H&E‐stained HCC sections, and to explore its prognostic relevance and underlying molecular ...
Long Chen   +7 more
wiley   +1 more source

Potential biomarkers for the prognosis of gastrointestinal stromal tumors. [PDF]

open access: yesWorld J Gastrointest Oncol
Sun YF, Cao XK, Wei Q, Gao YH.
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 4, Page 962-980, April 2026.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Light‐Triggered Antibody‐Photosensitizer Conjugates Disrupt P‐Glycoprotein Function to Reverse Multidrug Resistance

open access: yesAdvanced Therapeutics, Volume 9, Issue 4, April 2026.
Advanced ovarian cancer has a poor prognosis largely due to chemoresistance driven by ATP‐binding cassette (ABC) drug efflux transporters, especially P‐glycoprotein (P‐gp, or ABCB1). While photodynamic therapy (PDT) with FDA‐approved benzoporphyrin derivative (BPD) can inhibit ABC transporters, BPD alone lacks cancer selectivity.
Kathryn L. McNaughton   +6 more
wiley   +1 more source

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