Results 61 to 70 of about 87,116 (304)
A rare case of mesenteric gastrointestinal stromal tumor presenting as acute abdomen
Nigerian Journal of Surgery, 2017 Gastrointestinal stromal tumours (GIST) are rare tumours arising from mesenchyme of gastrointestinal tract and overexpress C-kit protein. Mainly seen in stomach and small bowel. Mesenteric GIST are rarely reported as they constitute less than 1% of total
Anant Sadanand Ramani +2 more
doaj +1 more source
Studies on the treatment of malignant tumors with fibroblast-inhibiting agent III. Effects of chloroquine on human cancers [PDF]
, 1964 A fibroblast-inhibiting agent, chloroquine, used in the treatment of animal tumors led to a reasonably good result, and this approach was extended to the treatment of human cancers.
Hiraki, Kiyoshi, Kimura, Ikuro
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma. [PDF]
, 2017 Intratumoral heterogeneity (ITH) is a prominent feature of kidney cancer. It is not known whether it has utility in finding associations between protein expression and clinical parameters. We used ITH that is detected by immunohistochemistry (IHC) to aid
Devarajan, Karthik +10 more
core +3 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Study of gastrointestinal stromal tumors with c-kit immunostaining
Journal of Pathology of Nepal, 2011 Background: Mutation of the C-KIT oncogene is the central event in gastrointestinal stromal tumors which are the most common mesenchymal tumors arising from the tubular gastrointestinal tract.
B Sigdel, S Vaidya, Sabira KC
doaj +1 more source
Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]
, 2016 Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G +4 more
core +1 more source
Advanced Materials Technologies, EarlyView.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Gastrointestinal stromal tumor: case report
Archivo Médico de Camagüey, 2018 Background: the gastrointestinal stromal tumors, are mesenchymal tumors that appear in any place of gastrointestinal tract. Many of them can be pediculate and difficult pre-operatory diagnosis.
Yon Luis Trujillo-Pérez +4 more
doaj
Radiomics in the differential diagnosis of gastrointestinal stromal tumors and leiomyomas. A literature review [PDF]
Digital Diagnostics. BACKGROUND: A limited number of studies have been conducted in Russian and world literature on the differential diagnosis of gastrointestinal stromal tumors with other intra-abdominal tumors.
Elina A. Martirosyan +3 more
doaj +1 more source