Nutrition and the gastrointestinal tract [PDF]
In this year’s issue, we again have a high-calibre collection of topical reviews. Gracie and Ford commence with an assessment of the role of symbiotics (i.e. probiotics and prebiotics given together) in patients with irritable bowel syndrome. They first review the many randomized trials of probiotics and the significant and persistent reductions in ...
Forbes, Alastair+1 more
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Metformin and the gastrointestinal tract [PDF]
Metformin is an effective agent with a good safety profile that is widely used as a first-line treatment for type 2 diabetes, yet its mechanisms of action and variability in terms of efficacy and side effects remain poorly understood. Although the liver is recognised as a major site of metformin pharmacodynamics, recent evidence also implicates the gut
McCreight, Laura J.+2 more
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Microbiota in the Gastrointestinal Tract [PDF]
Gut microbiota are permanent residents of humans with the highest concentrations being found in human colon. Humans get the first contact with bacteria at delivery, and microbiota are subject of permanent change during the life. The individual microbiota pattern is highly variable and varying environmental conditions, e.g., diets, antigen exposure ...
Walburga Dieterich+2 more
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Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
A Gil-Izquierdo+53 more
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Computer-Assisted Segmentation of Videocapsule Images Using Alpha-Divergence-Based Active Contour in the Framework of Intestinal Pathologies Detection [PDF]
Visualization of the entire length of the gastrointestinal tract through natural orifices is a challenge for endoscopists. Videoendoscopy is currently the “gold standard” technique for diagnosis of different pathologies of the intestinal tract.
Dray, X.+6 more
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Intestinal macromolecular transport supporting adaptive immunity [PDF]
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
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Cannabis and the Gastrointestinal Tract
Cannabis has been used for its medicinal purposes since ancient times. Its consumption leads to the activation of Cannabis receptors CB1 and CB2 that, through specific mechanisms can lead to modulation and progression of inflammation or repair. The novel findings are linked to the medical use of Cannabis in gastrointestinal (GI) system.
Manuela G. Neuman, Lawrence Cohen
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Purinergic signaling in the gastrointestinal tract [PDF]
Geoffrey Burnstock completed a BSc at King's College London and a PhD at University College London. He held postdoctoral fellowships with Wilhelm Feldberg (National Institute for Medical Research), Edith Bülbring (University of Oxford) and C.
Burnstock, G
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Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]
Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R.+2 more
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Upper gastrointestinal tract bleeding in Ilorin, Nigeria - a report of 30 cases [PDF]
Background: Upper gastrointestinal tract bleeding refers to blood loss within the intraluminal gastrointestinal tract from any location between the upper oesophagus to the duodenum at the ligament of Treitz.
Jimoh, A.A.G, Olokoba, A.B, Olokoba, L.B
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