Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]
, 2019 Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R. +2 more
core +1 more source
Protein degradation technology: a strategic paradigm shift in drug discovery
Journal of Hematology & Oncology, 2021 Targeting pathogenic proteins with small-molecule inhibitors (SMIs) has become a widely used strategy for treating malignant tumors. However, most intracellular proteins have been proven to be undruggable due to a lack of active sites, leading to a ...
Haobin Li +5 more
doaj +1 more source
Extensive transmission of microbes along the gastrointestinal tract
bioRxiv, 2018 The gastrointestinal tract is abundantly colonized by microbes, yet the translocation of oral species to the intestine is considered a rare aberrant event, and a hallmark of disease.
T. Schmidt +16 more
semanticscholar +1 more source
Cannabis and the Gastrointestinal Tract
Journal of Pharmacy & Pharmaceutical Sciences, 2020 Cannabis has been used for its medicinal purposes since ancient times. Its consumption leads to the activation of Cannabis receptors CB1 and CB2 that, through specific mechanisms can lead to modulation and progression of inflammation or repair. The novel findings are linked to the medical use of Cannabis in gastrointestinal (GI) system.
Manuela G. Neuman, Lawrence Cohen
openaire +5 more sources
Radiological findings spectrum of asymptomatic coronavirus (COVID-19) patients
The Egyptian Journal of Radiology and Nuclear Medicine, 2020 Background Radiological examinations of COVID-19 positive patients play a vital role in early diagnosis and assessment of disease course, as most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns ...
Rasha Mostafa Mohamed Ali +1 more
doaj +1 more source
Post-COVID-19 pneumonia lung fibrosis: a worrisome sequelae in surviving patients
The Egyptian Journal of Radiology and Nuclear Medicine, 2021 Background Progressive fibrotic lung disease is one of the possible consequences of COVID-19 pulmonary pneumonia, and it is one of the most worrying long-term complications. Pulmonary fibrosis is associated with non-reversible lung dysfunction.
Rasha Mostafa Mohamed Ali +1 more
doaj +1 more source
Gastrointestinal Amyloidosis: Diagnostic Approach and Treatment [PDF]
, 2015 Amyloidosis is a disease marked by deposition of misfolded proteins, known as amyloids, in the extracellular space, including gastrointestinal tract.
Budyono, C. (Catarina) +2 more
core +2 more sources
INFOGEST static in vitro simulation of gastrointestinal food digestion
Nature Protocols, 2019 Developing a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract.
A. Brodkorb +34 more
semanticscholar +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2021 Background Crohn’s disease (CD) is a ruinous bowel disease, which, if left uncured, leads to penetrating bowel complications. Computed tomography enterography (CTE) is nowadays accepted as a principal modality for the assessment of small bowel diseases ...
Rasha Mostafa Mohamed Ali +1 more
doaj +1 more source
Computer-Assisted Segmentation of Videocapsule Images Using Alpha-Divergence-Based Active Contour in the Framework of Intestinal Pathologies Detection [PDF]
, 2014 Visualization of the entire length of the gastrointestinal tract through natural orifices is a challenge for endoscopists. Videoendoscopy is currently the “gold standard” technique for diagnosis of different pathologies of the intestinal tract.
Dray, X. +6 more
core +6 more sources