Results 61 to 70 of about 2,027,318 (403)

Primary Gastrointestinal Tract Lymphoma [PDF]

, 2010
Extranodular lymphomacanbe found in almostallorgan. One third of the cases found in gastrointestinal(GI) tract, whichisthemost commonformofextranodular lymphoma.All thesubtypesof lymphomamayoccurasprimarylesionalongingastrointestinaltract ...
Samosir, D. R. (David), Simadibrata, M. (Marcellus)   +1 more
core  

Phascolarctobacterium faecium abundant colonization in human gastrointestinal tract.

Experimental and Therapeutic Medicine, 2017
Phascolarctobacterium can produce short-chain fatty acids, including acetate and propionate, and can be associated with the metabolic state and mood of the host.
Feifan Wu, Xianfeng Guo, Jiachun Zhang, Min Zhang, Zihao Ou, Yongzheng Peng   +5 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8+ T cells in dMMR/MSI-H gastric cancer

Scientific Reports
Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) gastric cancer (GC) exhibits an immune-active tumor microenvironment (TME) compared to MMR proficient (pMMR)/microsatellite stable/Epstein-Barr virus-negative [EBV (−)] GC.
Ryo Kanoda, Shotaro Nakajima, Satoshi Fukai, Motonobu Saito, Katsuharu Saito, Hiroya Suzuki, Tomohiro Kikuchi, Azuma Nirei, Hirokazu Okayama, Kosaku Mimura, Hiroyuki Hanayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono   +14 more
doaj   +1 more source

Trametes robiniophila Murr Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Modulating Tumor Microenvironment

Frontiers in Pharmacology, 2022
Trametes robiniophila Murr (TRM) is a traditional Chinese medicine which has been used in clinics for enhancing immunity and improving the efficacy of chemotherapy. However, the mechanisms of action of TRM are unknown.
Jing-Li Xu, Li Yuan, Li Yuan, Li Yuan, Can Hu, Chun-Yan Weng, Han-Dong Xu, Yun-Fu Shi, Ling Huang, Ling Huang, Ling Huang, Jie-Er Ying, Jie-Er Ying, Jie-Er Ying, Zhi-Yuan Xu, Zhi-Yuan Xu, Zhi-Yuan Xu, Jiang-Jiang Qin, Jiang-Jiang Qin, Jiang-Jiang Qin, Xiang-Dong Cheng, Xiang-Dong Cheng, Xiang-Dong Cheng   +22 more
doaj   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Moderate Physical Exercise Activates ATR2 Receptors, Improving Inflammation and Oxidative Stress in the Duodenum of 2K1C Hypertensive Rats

Frontiers in Physiology, 2021
Background: In addition to the cardiovascular and renal systems, the gastrointestinal tract also contains angiotensin ATR1a, ATR1b, and ATR2. We previously observed that the 2Kidney-1Clip hypertension model elicits physical exercise and gastrointestinal ...
Alda Cássia Alves da Silva, Alda Cássia Alves da Silva, Juliana Soares Severo, Juliana Soares Severo, Brenda Lois Barros dos Santos, Pedro Henrique Moraes Mendes, Lívia Maria Soares Nobre, Ana Patrícia de Oliveira, Francisco Cleber Silva Ferreira, Jand Venes Rolim Medeiros, Jand Venes Rolim Medeiros, Roberto Cesar Lima-Junior, Alexandre Havt, Raimundo Campos Palheta-Junior, Armênio Aguiar dos Santos, Moisés Tolentino, Moisés Tolentino, Moisés Tolentino   +17 more
doaj   +1 more source

Microbial Ecology along the Gastrointestinal Tract

Microbes and Environments, 2017
The ecosystem of the human gastrointestinal (GI) tract traverses a number of environmental, chemical, and physical conditions because it runs from the oral cavity to the anus.
Ethan T. Hillman, Hang Lu, Tianming Yao, C. Nakatsu   +3 more
semanticscholar   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

The impact of CLDN18.2 expression on effector cells mediating antibody-dependent cellular cytotoxicity in gastric cancer

Scientific Reports
Activating antibody-dependent cellular cytotoxicity (ADCC) by targeting claudin-18 isoform 2 (CLDN18.2) using zolbetuximab, a monoclonal antibody against CLDN18.2, has been considered a promising novel therapeutic strategy for gastric cancer (GC ...
Akira Matsuishi, Shotaro Nakajima, Motonobu Saito, Katsuharu Saito, Satoshi Fukai, Hideaki Tsumuraya, Ryo Kanoda, Tomohiro Kikuchi, Azuma Nirei, Akinao Kaneta, Hirokazu Okayama, Kosaku Mimura, Hiroyuki Hanayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono   +16 more
doaj   +1 more source