Results 1 to 10 of about 25,632 (110)
Nonfimbrial Adhesin Mutants Reveal Divergent Escherichia coli O157:H7 Adherence Mechanisms on Human and Cattle Epithelial Cells. [PDF]
Int J Microbiol, 2021 Shiga toxin‐producing, enterohemorrhagic Escherichia coli (EHEC) serotype O157:H7 is a major foodborne pathogen causing symptoms ranging from simple intestinal discomfort to bloody diarrhea and life‐threatening hemolytic uremic syndrome in humans.
Moreau MR +6 more
europepmc +2 more sources
Island Studies Journal, 2023 Researchers are beginning to explore the impact of the COVID-19 pandemic on island populations, but little is known about the experiences of the residents of Nantucket and Martha's Vineyard in the Northeast region of the United States.
Nicole Kras, Jennifer Keenan
doaj +1 more source
A South-South Tango: China’s Soft Power Relations With Fiji Since 1975
Island Studies Journal, 2023 This paper on China's soft power relations with Fiji since 1975 provides an on-the-ground view of the scope of China's Aid, Foreign Direct Investments (FDI) and Trade with Fiji to provide an alternative narrative for China's increased presence in the ...
Asinate Mausio
doaj +1 more source
Elucidating the toxic effect and disease mechanisms associated with Lyso-Gb3 in Fabry disease
Human Molecular Genetics, 2023 Fabry disease stems from a deficiency of alpha-galactosidase and results in the accumulation of globotriaosylceramide (Gb3). However, the production of its deacylated form globotriaosylsphingosine (lyso-Gb3) is also observed and its plasma levels have ...
Valeria Nikolaenko +3 more
semanticscholar +1 more source
Journal of Translational Medicine, 2023 Background Fabry disease (FD) is a rare lysosomal storage disorder caused by mutations in the GLA gene, resulting in reduced or lack of α-galactosidase A activity.
H. Elsaid +9 more
semanticscholar +1 more source
A Shiga Toxin B-Subunit-Based Lectibody Boosts T Cell Cytotoxicity towards Gb3-Positive Cancer Cells
Cells, 2023 Aberrant glycosylation plays a crucial role in tumour progression and invasiveness. Tumour-associated carbohydrate antigens (TACAs) represent a valuable set of targets for immunotherapeutic approaches.
Jana Tomisch +10 more
semanticscholar +1 more source
Sustainable Creative Tourism on Islands and the Pandemic: The Creatour Azores Project
Island Studies Journal, 2023 As the impact of the COVID-19 pandemic was felt worldwide, the tourism sector was forced to seek ways of reinventing itself. Two decades prior to this crisis, in varied rural areas and island contexts, small-scale, community-based creative tourism had ...
Alexandra Baixinho +6 more
doaj +1 more source
Journal of Clinical Medicine, 2023 Background: Fabry disease cardiomyopathy (FDCM) has manifested some resistance to enzyme replacement therapy (ERT), particularly in its advanced phase. Recently, myocardial inflammation of autoimmune origin has been demonstrated in FDCM.
A. Frustaci +5 more
semanticscholar +1 more source
Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells
Cellular and Molecular Life Sciences, 2022 The link between cancer and aberrant glycosylation has recently become evident. Glycans and their altered forms, known as tumour-associated carbohydrate antigens (TACAs), are diverse, complex and difficult to target therapeutically. Lectins are naturally
A. V. Meléndez +10 more
semanticscholar +1 more source
Lyso-Gb3 associates with adverse long-term outcome in patients with Fabry disease
Journal of Medical Genetics, 2021 Background Fabry disease (FD) is a rare X-linked lysosomal storage disease caused by mutations in the α-galactosidase A gene (GLA) leading to deficiency of α-galactosidase A and ultimately in progressive glycosphingolipid accumulation, especially ...
A. Nowak +4 more
semanticscholar +1 more source