Results 161 to 170 of about 31,524 (206)
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Gb3-Coated Bovine Milk Exosomes as a Practical Neutralizer for Shiga Toxin
ACS Applied Bio Materials, 2023Shiga toxin (Stx) is associated with foodborne infections of some Shigella spp. and Shiga toxin-producing Escherichia coli (STEC), leading to life-threatening hemolytic uremic syndrome (HUS).
Zhimeng Wu, Zhifang Zhou, Haofei Hong
exaly +4 more sources
Peptides binding to a Gb3 mimic selected from a phage library
Biochimica Et Biophysica Acta - General Subjects, 2004Peptides binding to a Gb3 mimic were selected from 12-mer peptide library. The self-assembled monolayer (SAM) of a Gb3 mimic was formed on the gold surface, and biopanning was carried out with the phage display peptide library. After three rounds of biopanning, four individual sequences were obtained from 10 phage clones, and the selected peptides ...
Yoshiko Miura +2 more
exaly +3 more sources
Expression of the glycolipid globotriaosylceramide (Gb3) in testicular carcinoma in situ
Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin, 1995Changes in the cell membrane glycolipid composition and metabolism are frequently associated with carcinogenesis. The accumulation of globo-series glycolipids is the most notable change of the germ cell glycolipid composition observed in testicular tumours.
Joelle Wiels +2 more
exaly +3 more sources
Biochemical and Biophysical Research Communications - BBRC, 2022
N-glycosylation is a posttranslational modification that influences many protein properties, such as bioactivity, folding or solubility. The same principles apply to key enzymes in glycosylation pathways, including glycosyltransferases, that also ...
Krzysztof Mikołajczyk +4 more
semanticscholar +1 more source
N-glycosylation is a posttranslational modification that influences many protein properties, such as bioactivity, folding or solubility. The same principles apply to key enzymes in glycosylation pathways, including glycosyltransferases, that also ...
Krzysztof Mikołajczyk +4 more
semanticscholar +1 more source
High-Relaxivity Molecular MRI Contrast Agent to Target Gb3-Expressing Cancer Cells.
Bioconjugate chemistry, 2022Targeted contrast agents (CAs) can improve magnetic resonance imaging (MRI) for accurate cancer diagnosis. In this work, we used the Shiga toxin B-subunit (STxB) as a targeting agent, which binds to Gb3, a glycosphingolipid highly overexpressed on the ...
S. Deville-Foillard +6 more
semanticscholar +1 more source
Journal of Chemical Theory and Computation, 2021
The recognition of carbohydrate receptors on host cell membranes by pathogenic lectins is a crucial step in the microbial invasion. Two bacterial lectins, the B-subunit of Shiga toxin from Shigella dysenteria (StxB) and lectin I from Pseudomonas ...
Raisa Kociurzynski +3 more
semanticscholar +1 more source
The recognition of carbohydrate receptors on host cell membranes by pathogenic lectins is a crucial step in the microbial invasion. Two bacterial lectins, the B-subunit of Shiga toxin from Shigella dysenteria (StxB) and lectin I from Pseudomonas ...
Raisa Kociurzynski +3 more
semanticscholar +1 more source
Chemoenzymatic Syntheses of iGb3 and Gb3
Organic Letters, 2006Efficient chemoenzymatic syntheses of iGb3 and Gb3 have been developed. Isoglobotrihexose and globotrihexose were enzymatically synthesized by a three-enzyme system in both solid and solution phases. Then iGb3 and Gb3 were chemically synthesized by coupling of the corresponding trisaccharides with lipid.
Qingjia, Yao +4 more
openaire +2 more sources
Clinical Genetics, 2021
The purpose of this study was to examine the applicability of the use of samples in dried blood spot (DBS) for the definitive diagnosis of Fabry disease (FD) in males and females and to compare the diagnostic role of α‐galactosidase A activity (α‐Gal A),
Rocío Delarosa-Rodríguez +7 more
semanticscholar +1 more source
The purpose of this study was to examine the applicability of the use of samples in dried blood spot (DBS) for the definitive diagnosis of Fabry disease (FD) in males and females and to compare the diagnostic role of α‐galactosidase A activity (α‐Gal A),
Rocío Delarosa-Rodríguez +7 more
semanticscholar +1 more source
Comparison of Total Lipid Composition in Gb3‐Positive and Gb3‐Deficient Burkitt's Lymphoma Cells
Journal of Liquid Chromatography & Related Technologies, 2005Abstract Thin-layer chromatography was used to compare the glycolipid, phospholipid, and neutral lipid compositions of the globotriaosylceramide (Gb3)‐positive Burkitt's lymphoma Daudi cell line and the Gb3‐deficient Daudi‐derived VT500 cell line. Glycolipid compositions were determined by co‐migration of lipids with glycosphingolipid standards and ...
Mark Maloney +3 more
openaire +1 more source