Results 51 to 60 of about 18,064 (218)
Journal of Patient-Reported Outcomes, 2020 Background Approximately 7–10% of Parkinson’s disease (PD) patients carry a GBA (Glucocerebrosidase) mutation (GBA-PD patients), which may influence the disease’s clinical course.
N. Bonner +7 more
doaj +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT Despite the growing emphasis on sustainable finance in today's corporate landscape, its impact on product responsibility remains underexplored, particularly the moderating role of board environmental expertise. This study addresses these gaps by examining non‐financial companies listed on the London Stock Exchange, chosen for the UK's ...
Bright Akwasi Gyamfi +4 more
wiley +1 more source
Gambogic acid inhibits LPS-induced macrophage pro-inflammatory cytokine production mainly through suppression of the p38 pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): In traditional Chinese medicine, gamboge can detoxify bodies, kill parasites, and act as a hemostatic agent. Recent studies have demonstrated that gambogic acid (GBA) suppressed inflammation in arthritis, and also presented antitumor effect.
Ma Jianjun +6 more
doaj +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A π‐conjugated carbazole (p‐CBZ) layer is electro‐polymerized on BiVO4 to form a p–n heterojunction that enhances charge separation and suppresses surface recombination, while a NiOOH co‐catalyst accelerates oxygen evolution kinetics. The synergistic BVO/p‐CBZ/NiOOH photoanode delivers a high photocurrent density and long‐term stability for efficient ...
Lakshman Sundar Arumugam +11 more
wiley +1 more source
Clinical Parkinsonism & Related DisordersBackground: Cognitive impairment is a major non-motor complication of Parkinson’s disease (PD). GBA mutations are associated with an increased risk, with PD-GBA+ patients typically showing earlier disease onset and faster cognitive decline.
Chiara Longo +14 more
doaj +1 more source
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Epilepsia Open, EarlyView.Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola +3 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang +22 more
wiley +1 more source
Classification of GBA Variants and Their Effects in Synucleinopathies
Movement Disorders, 2019 This is the peer reviewed version of the following article: [Gan‐Or, Z., Alcalay, R.N., Makarious, M.B., Scholz, S.W., and Blauwendraat, C. (2019). Classification of GBA Variants and Their Effects in Synucleinopathies. Movement Disorders 34, 1581–1582.], which has been published in final form at https://doi.org/10.1002/mds.27803.
Gan‐Or, Ziv +4 more
openaire +3 more sources
Journal of Clinical Laboratory Analysis, EarlyView.Verification study enabled the detection of HIV false reactivity ranging from 0‐4% across rapid diagnostic tests. A reliable three‐tests algorithm ranked First Response HIV 1‐2‐0 Card, First Response HIV1+2/Syphilis Combo or STANDARD Q as suitable test 1 to mitigate false positive events. As countries move toward HIV elimination, implementing the three‐
Rogers Ajeh Awoh +34 more
wiley +1 more source