Results 61 to 70 of about 25,057 (208)

Magnetoelectric BaTiO3/CoFe2O4 Thin‐Film Meshes for Neuronal Differentiation

open access: yesAdvanced Science, EarlyView.
We engineer an epitaxial BaTiO3/CoFe2O4 magnetoelectric mesh that overcomes boundary‐induced mechanical clamping. Progressively reducing the mechanical constraint, from substrate‐clamped to PDMS‐transferred and ultimately freestanding, enhances magnetic‐to‐electric transduction and strengthens magnetoelectric coupling.
Mathieu Mirjolet   +13 more
wiley   +1 more source

GBA variants in REM sleep behavior disorder: a multicenter study [PDF]

open access: yes, 2020
Objective: To study the role of GBA variants in the risk for isolated rapid-eye-movement (REM)-sleep behavior disorder (iRBD) and conversion to overt neurodegeneration.
Asayesh, Farnaz   +97 more
core   +1 more source

Intelligent Systems for Inorganic Nanomaterial Synthesis

open access: yesNanomaterials
Inorganic nanomaterials are pivotal foundational materials driving traditional industries’ transformation and emerging sectors’ evolution. However, their industrial application is hindered by the limitations of conventional synthesis methods, including ...
Chang’en Han   +5 more
doaj   +1 more source

Quality of Plant-Based Ground Beef Alternatives in Comparison with Ground Beef of Various Fat Levels

open access: yesMeat and Muscle Biology, 2021
The objective of this study was to compare the quality characteristics of current plant-based protein ground beef alternatives (GBA) to ground beef (GB) patties of varying fat percentages.
Anthony J. Tarpoff   +10 more
doaj   +2 more sources

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

open access: yesAdvanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu   +7 more
wiley   +1 more source

Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis

open access: yesAdvanced Science, EarlyView.
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko   +8 more
wiley   +1 more source

Dataset related to article "Impulse control behavior in GBA-mutated parkinsonian patients"

open access: yes, 2021
This record contains raw data related to article “Impulse control behavior in GBA-mutated parkinsonian patients" Objective: To assess the prevalence and phenomenology of Impulse control behavior (ICB) in Parkinson's disease (PD) patients carrying ...
Federica Invernizzi   +4 more
core   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng   +7 more
wiley   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

open access: yesAdvanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye   +15 more
wiley   +1 more source

CARDIOVASCULAR AUTONOMIC IMPAIRMENT IN GBA PARKINSONIAN PATIENTS [PDF]

open access: yes
Background: Mutations in the Beta-glucocerebrosidase (GBA) gene are the most common genetic risk factor for Parkinson’s disease (PD). GBA-associated PD (GBA-PD) has been linked to a higher prevalence of non-motor symptoms compared to idiopathic PD (I-PD),
COCCO, ANTONIANGELA
core   +1 more source

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