Results 141 to 150 of about 244,777 (197)

Identification of hsa-miR-144-3p as a novel immunotherapeutic target for glioblastoma based on disulfidptosis-related analysis. [PDF]

Discov Oncol
Li M, Li J, Yuan Y, Li Z, Liu G, Guo Y, Zhou Y, Chai Z, Wang C, Fu X, Bu X, Kong XT, Ma C.   +12 more
europepmc   +1 more source

Ferroptosis and metabolic reprogramming in the immunosuppressive microenvironment of glioblastoma: emerging mechanisms and novel strategies. [PDF]

Front Immunol
Han L, Wang Z, Jiang Y, Zhou H, Zhou H.
europepmc   +1 more source

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Seeing the GBM diversity spectrum

Nature Cancer, 2021
The complexity of glioblastoma is becoming increasingly recognized. Three recent studies used single-cell approaches that integrate cellular states, transcriptional trajectories, and metabolic alterations to uncover multiple dimensions of cellular and molecular heterogeneity and provide a framework for additional functional investigation and ...
Christopher G. Hubert, Justin D. Lathia
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Current Status of the GBM Project

AIP Conference Proceedings, 2007
One of the scientific goals of the Large‐Area Telescope (LAT) on GLAST is the study of gamma‐ray bursts (GRBs) in the energy range from ∼20 MeV to ∼300 GeV. In order to extend the energy measurement towards lower energies a secondary instrument, the GLAST Burst Monitor (GBM), will measure GRBs from ∼10 keV to ∼30 MeV and will therefore allow the ...
Lichti, G., Bhat, N., Briggs, M., Connaughton, V., Diehl, R., Fishman, G., Greiner, J., Kippen, R., Kouveliotou, C., Meegan, C., Paciesas, W., Preece, R., Steinle, H., Kienlin, A.   +13 more
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Immune checkpoint inhibitors in GBM

Journal of Neuro-Oncology, 2021
The purpose of this review is to summarize recent updates regarding immune checkpoint inhibitor therapy in GBM patients including updates in brain immunology, clinical trials, mechanisms of resistance, and biomarkers of response.PubMed was searched to identify recent relevant articles on immune checkpoint inhibitor therapy as it pertains to GBM ...
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Opposing roles of PGD2 in GBM

Prostaglandins & Other Lipid Mediators, 2018
The World Health Organization classifies glioblastoma (GBM) as a grade IV astrocytoma. Despite the advances in chemotherapy, surgery, and radiation treatments that improve a patient's length of survival, the overall trajectory of the disease remains unchanged. GBM cells produce significant levels of various types of bioactive lipids.
Matthew Thomas, Ferreira, Renata Nascimento, Gomes, Alexandros Theodoros, Panagopoulos, Fernando Gonçalves, de Almeida, José Carlos Esteves, Veiga, Alison, Colquhoun   +5 more
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The validity of EORTC GBM prognostic calculator on survival of GBM patients in the West of Scotland

British Journal of Neurosurgery, 2013
It is now accepted that the addition of temozolomide to radiotherapy in the treatment of patients with newly diagnosed glioblastoma multiforme (GBM) significantly improves survival. In 2008, a subanalysis of the original study data was performed, and an online "GBM Calculator" was made available on the European Organisation for Research and Treatment ...
Mario, Teo, Brian, Clark, Mairi, MacKinnon, Willie, Stewart, James, Paul, Jerome, St George   +5 more
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GBM Immunotherapy: Macrophage Impacts

Immunological Investigations
Glioblastoma (GBM) is an extremely aggressive form of brain tumor with low survival rates. Current treatments such as chemotherapy, radiation, and surgery are problematic due to tumor growth, invasion, and tumor microenvironment. GBM cells are resistant to these standard treatments, and the heterogeneity of the tumor makes it difficult to find a ...
Nina Loginova, Denis Aniskin, Peter Timashev, Ilya Ulasov, Rajesh Kumar Kharwar   +4 more
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Anti-GBM disease in pregnancy

BMJ Case Reports
We present the case of a pregnant woman in her 20s who presented in her second trimester with severe pulmonary haemorrhage and dialysis-dependent acute kidney failure due to antiglomerular basement membrane (GBM) disease. Responding to therapy, she recovered kidney function and delivered a baby.
Abdul Hadi, Kafagi, Anna S, Li, David, Jayne, Silke R, Brix   +3 more
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