Results 11 to 20 of about 233,509 (250)

GLAST’s GBM Burst Trigger

AIP Conference Proceedings, 2004
The GLAST Burst Monitor (GBM) will detect and localize bursts for the GLAST mission, and provide the spectral and temporal context in the traditional 10 keV to 25 MeV band for the high energy observations by the Large Area Telescope (LAT). The GBM will use traditional rate triggers in up to three energy bands, and on a variety of timescales between 16 ...
Band, D., Briggs, M., Connaughton, V., Kippen, M., Preece, R.   +4 more
openaire   +2 more sources

Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment [PDF]

, 2019
The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit.
Pastor Loro, Ángel Manuel, Rodríguez Matarredona, Esperanza   +1 more
core   +1 more source

Differentiation of Human GBM From Non-GBM Brain Tissue With Polarization Imaging Technique

Frontiers in Oncology, 2022
As for optical techniques, it is difficult for the 5-aminolevulinic (5-ALA) fluorescence guidance technique to completely detect glioma due to residual cells in the blind area and the dead angle of vision under microscopy. The purpose of this research is to characterize different microstructural information and optical properties of formalin-soaked ...
Yi-Rong Liu, Yi-Rong Liu, Hong-Hui He, Jian Wu   +3 more
openaire   +3 more sources

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay [PDF]

, 2014
The molecular mechanisms by which glioblastoma multiforme (GBM) refracts and becomes resistant to radiotherapy treatment remains largely unknown. This radioresistance is partly due to the presence of hypoxic regions, which are frequently found in GBM ...
Cerasani, Manuela, Ciccarelli, Carmela, Di Cesare, Ernesto, Di Genova, Daniela, Festuccia, Claudio, Ficorella, Corrado, Fratticci, Amato, Gravina, Giovanni Luca, Mancini, Marta, Marampon, Francesco, Popov, Vladimir M, Zani, Bianca Maria   +11 more
core   +1 more source

Spectral and temporal analysis of the joint Swift/BAT-Fermi/GBM GRB sample [PDF]

, 2011
Using the gamma-ray bursts simultaneously detected by Swift/BAT and Fermi/GBM we performed a joint spectral and temporal analysis of the prompt emission data and confirm the rough correlation between the BAT-band photon index Gamma_BAT and the peak ...
Amati, Amati, Amati, Band, Band, Barthelmy, Barthelmy, Barthelmy, Barthelmy, Barthelmy, Barthelmy, Barthelmy, Barthelmy, Barthelmy, Baumgartner, Baumgartner, Baumgartner, Bing Zhang, Bissaldi, Cui, Cummings, Cummings, Cummings, Cummings, Enwei Liang, Francisco J. Virgili, Gehrels, Ghirlanda, Ghirlanda, Ghirlanda, Gruber, Kocevski, Kouveliotou, Krimm, Krimm, Krimm, Li, Liang, Markwardt, Markwardt, Markwardt, Markwardt, Markwardt, Nakar, Nava, Palmer, Palmer, Palmer, Palmer, Preece, Sakamoto, Sakamoto, Sakamoto, Sakamoto, Sakamoto, Sakamoto, Scargle, Stamatikos, Stamatikos, Stamatikos, Stamatikos, Ukwatta, Ukwatta, Ukwatta, Ukwatta, Ying Qin, Yonetoku, Zhang, Zhang, Zhang, Zhang   +70 more
core   +1 more source

Relation of exact Gaussian basis methods to the dephasing representation: Theory and application to time-resolved electronic spectra [PDF]

, 2013
We recently showed that the Dephasing Representation (DR) provides an efficient tool for computing ultrafast electronic spectra and that further acceleration is possible with cellularization [M. \v{S}ulc and J. Van\'i\v{c}ek, Mol. Phys. 110, 945 (2012)].
Hernández, Henar, Martínez, Todd J., Vaníček, Jiří, Šulc, Miroslav   +3 more
core   +2 more sources

Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers

European Journal of Pharmaceutics and Biopharmaceutics, 2021
Glioblastoma multiforme (GBM) is the most common primary brain cancer. GBM has aggressive development, and the pharmacological treatment remains a challenge due to GBM anatomical characteristics' (the blood-brain barrier and tumor microenvironment) and the increasing resistance to marketed drugs, such as temozolomide (TMZ), the first-line drug for GBM ...
Delello Di Filippo, Leonardo, Hofstätter Azambuja, Juliana, Paes Dutra, Jessyca Aparecida, Tavares Luiz, Marcela, Lobato Duarte, Jonatas, Nicoleti, Luiza Ribeiro, Olalla Saad, Sara Teresinha, Chorilli, Marlus   +7 more
openaire   +4 more sources

Monitoring the Low-Energy Gamma-Ray Sky Using Earth Occultation with GLAST GBM [PDF]

, 2007
Long term all-sky monitoring of the 20 keV – 2 MeV gamma-ray sky using the Earth occultation technique was demonstrated by the BATSE instrument on the Compton Gamma Ray Observatory.
Case, G. L., Cherry, M. L., Kippen, R. M., Ling, J. C., Radocinski, R. G., Wheaton, W. A., Wilson-Hodge, C. A.   +6 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source