Results 11 to 20 of about 244,777 (197)
Master Regulators, Regulatory Networks, and Pathways of Glioblastoma Subtypes [PDF]
Cancer Informatics, 2014 Glioblastoma multiforme (GBM) is the most common malignant brain tumor. GBM samples are classified into subtypes based on their transcriptomic and epigenetic profiles.
Serdar Bozdag +3 more
doaj +4 more sources
Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells [PDF]
Redox Biology, 2019 Radiotherapy (RT) is the major modality for control of glioblastoma multiforme (GBM), the most aggressive brain tumor in adults with poor prognosis and low patient survival rate.
Bowen Xie, Lu Zhang, Nian Jiang
exaly +3 more sources
The role of celecoxib in glioblastoma treatment: a review of literature [PDF]
World Cancer Research Journal, 2020 Objective: Glioblastoma (GB) is the most aggressive and lethal type of brain tumor. Despite the standard treatments and improvements, the overall survival (OS) and progression free survival (PFS) are not optimal.
F. Tavakolian +3 more
doaj +1 more source
The Madeiran laurel forest endemic Goodyera macrophylla (Orchidaceae) is related to American orchids
Anales del Jardín Botánico de Madrid, 2021 Macaronesian laurel forests harbour many herbs and laurophyllous trees with Mediterranean/European or Macaronesian affinities. Traditionally, the origin of these taxa has been explained by the relict hypothesis interpreting these taxa as relics of ...
Mike Thiv +2 more
doaj +1 more source
The MiR-561 Suppresses Glioblastoma Cell Proliferation through C-myc Regulation [PDF]
Middle East Journal of Cancer, 2021 Background: Glioblastoma multiforme (GBM) is the most common primary malignat brain tumor in adults. The modulation of miRNA expression is considered both as controlling groundwork for cancer development and invasion and as a potential application in GBM-
Somayeh Karami +6 more
doaj +1 more source
Nature Cancer, 2021 Pseudouridine is the most abundant RNA modification, but its biological role remains poorly understood. A study now finds dysregulated pseudouridine synthase PUS7 in glioblastoma and demonstrates that pharmacological inhibition of PUS7 leads to reduced tumorigenesis, which underpins the therapeutic potential of targeting epitranscriptomic regulators in
Virginia Morón-Calvente, Sandra Blanco
openaire +3 more sources
Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma
OncoImmunology, 2021 T cell-engaging therapies involving bispecific T cell engager (BiTE) and chimeric antigen receptor T (CAR-T) cells have achieved great success in the treatment of hematological tumors.
Gaowei Li +12 more
doaj +1 more source
Anales del Jardín Botánico de Madrid, 2020 Schultz “Bipontinus” (1805-1867) described, in the Histoire Naturelle des Îles Canaries published by Webb and Berthelot in 1849, several forms of the Andryala pinnatifida complex, endemic to the Canary Islands, based on plant material collected by E ...
Maria Zita Ferreira +2 more
doaj +1 more source
Salinomycin-Loaded Iron Oxide Nanoparticles for Glioblastoma Therapy
Nanomaterials, 2020 Salinomycin is an antibiotic introduced recently as a new and effective anticancer drug. In this study, magnetic iron oxide nanoparticles (IONPs) were utilized as a drug carrier for salinomycin for potential use in glioblastoma (GBM) chemotherapy.
Mohammad Norouzi +3 more
doaj +1 more source
Cell Stress, 2022 Glioblastoma (GBM) is a fatal disease with recurrences often associated with radioresistance. Although often effective at treating newly diagnosed GBM, increasing evidence suggests that radiotherapy-induced alterations in tumor metabolism promote GBM ...
Claudia R. Oliva +3 more
doaj +1 more source