Results 41 to 50 of about 173,777 (119)

Verteporfin-Loaded Anisotropic Poly(Beta-Amino Ester)-Based Micelles Demonstrate Brain Cancer-Selective Cytotoxicity and Enhanced Pharmacokinetics

International Journal of Nanomedicine, 2019
James G Shamul,1,2,* Sagar R Shah,1–3,* Jayoung Kim,1,2 Paula Schiapparelli,3 Carla A Vazquez-Ramos,3 Ben J Lee,1,2 Kisha K Patel,1,2 Alyssa Shin,1,2 Alfredo Quinones-Hinojosa,3 Jordan J Green1,2,4–6 1Department of Biomedical Engineering ...
Shamul JG, Shah SR, Kim J, Schiapparelli P, Vazquez-Ramos CA, Lee BJ, Patel KK, Shin A, Quinones-Hinojosa A, Green JJ   +9 more
doaj  

Predicting Survival in Glioblastoma Using Gene Expression Databases: A Neural Network Analysis [PDF]

International Journal of Molecular and Cellular Medicine
Glioblastoma (GBM) is the most aggressive and lethal brain tumor. Artificial neural networks (ANNs) have the potential to make accurate predictions and improve decision making. The aim of this study was to create an ANN model to predict 15-month survival
Parisa Azimi, Taravat Yazdanian, Amirhosein Zohrevand, Abolhassan Ahmadiani   +3 more
doaj  

Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma

International Journal of Nanomedicine, 2020
Li Peng,1,2,* Yanling Liang,1,* Xinxin Zhong,1 Zhiman Liang,1,2 Yinghong Tian,3 Shuji Li,1 Jingxue Liang,4 Ransheng Wang,4 Yuqi Zhong,4 Yusheng Shi,5 Xingmei Zhang1 1Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao ...
Peng L, Liang Y, Zhong X, Liang Z, Tian Y, Li S, Liang J, Wang R, Zhong Y, Shi Y, Zhang X   +10 more
doaj  

Master Regulators, Regulatory Networks, and Pathways of Glioblastoma Subtypes

Cancer Informatics, 2014
Glioblastoma multiforme (GBM) is the most common malignant brain tumor. GBM samples are classified into subtypes based on their transcriptomic and epigenetic profiles.
Serdar Bozdag, Aiguo Li, Mehmet Baysan, Howard A. Fine   +3 more
doaj   +1 more source

Advances in synthetic lethality modalities for glioblastoma multiforme

Open Medicine
Glioblastoma multiforme (GBM) is characterized by a high mortality rate, high resistance to cytotoxic chemotherapy, and radiotherapy due to its highly aggressive nature.
Richard Seidu A.
doaj   +1 more source

Diagnostic Innovation vs. Sustainable Disposal: The Waste Dilemma in RT-qPCR Testing and Its Ecological and Financial Costs to Public Health

Proceedings
Introduction: RT-qPCR represents a crucial diagnostic innovation in the epidemiological surveillance of respiratory viruses such as SARS-CoV-2 and influenza [...]
Luan A. A. Santos, Edejan H. Paula, Farah C. Murtadha, Fernanda Y. G. O. Andrade, Fabiano J. Q. Costa, Grasiela A. Silva, Tânia P. Costa   +6 more
doaj   +1 more source

Implication of tumor morphology and MRI characteristics on the accuracy of automated versus human segmentation of GBM areas

Scientific Reports
An assessment scheme is proposed to evaluate GBM gross tumor core and T2-FLAIR hyper-intensity segmentations on preoperative multicentric MR images as a function of tumor morphology and MRI characteristics.
Valeria Cerina, Chiara Benedetta Rui, Andrea Di Cristofori, Davide Ferlito, Giorgio Carrabba, Carlo Giussani, Gianpaolo Basso, Elisabetta De Bernardi   +7 more
doaj   +1 more source

Tumor-infiltrating CD8+ sub-populations in primary and recurrent glioblastoma: An in-silico study

Heliyon
Background: Glioblastoma multiforme (GBM) remains an incurable primary brain tumor. CD8+ tumor-infiltrating lymphocytes (TILs) can target malignant cells; however, their anti-tumoral immune responses mostly do not lead to GBM rejection in GBM patients ...
Mahdi Abdoli Shadbad, Adib Miraki Feriz, Behzad Baradaran, Hossein Safarpour   +3 more
doaj   +1 more source

Histological grade 2 and non-contrast-enhancing phenotype provide prognostic information complementary to DNA methylation classification in TERTp-mutant molecular glioblastomas

Acta Neuropathologica Communications
Glioblastoma (GBM), IDH-wildtype, is the most common and aggressive primary brain tumor in adults. According to the 2021 WHO classification, IDH-wildtype diffuse gliomas with a TERT promoter (TERTp) mutation, EGFR amplification, or combined whole ...
Hiroyuki Sueyoshi, Kenji Fujimoto, Katsumi Fujita, Kazuhito Tanaka, Hirotaka Inoue, Rin Yamada, Takahiro Yamamoto, Yutaka Nakachi, Jun-ichiro Kuroda, Naoki Shinojima, Kazuya Iwamoto, Yoshiki Mikami, Akitake Mukasa   +12 more
doaj   +1 more source

Identification of Survival-Associated miRNA Signatures in Glioblastoma Using Next-Generation Sequencing. [PDF]

Noncoding RNA
Bakó A, Torner B, Géczi D, Penyige A, Pozsgai P, Birkó Z, Klekner Á.   +6 more
europepmc   +1 more source