Results 41 to 50 of about 244,777 (197)

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay [PDF]

open access: yes, 2014
The molecular mechanisms by which glioblastoma multiforme (GBM) refracts and becomes resistant to radiotherapy treatment remains largely unknown. This radioresistance is partly due to the presence of hypoxic regions, which are frequently found in GBM ...
Cerasani, Manuela   +11 more
core   +1 more source

Modelo de predicción del rendimiento académico para el curso de nivelación de la Escuela Politécnica Nacional a partir de un modelo de aprendizaje supervisado

open access: yesLatin-American Journal of Computing, 2021
En el presente artículo se aplica un modelo de aprendizaje automático supervisado que predice la probabilidad de que un estudiante de la Escuela Politécnica Nacional apruebe el curso de nivelación.
Karen Calva   +3 more
doaj  

Relation of exact Gaussian basis methods to the dephasing representation: Theory and application to time-resolved electronic spectra [PDF]

open access: yes, 2013
We recently showed that the Dephasing Representation (DR) provides an efficient tool for computing ultrafast electronic spectra and that further acceleration is possible with cellularization [M. \v{S}ulc and J. Van\'i\v{c}ek, Mol. Phys. 110, 945 (2012)].
Hernández, Henar   +3 more
core   +2 more sources

GLAST’s GBM Burst Trigger

open access: yesAIP Conference Proceedings, 2004
The GLAST Burst Monitor (GBM) will detect and localize bursts for the GLAST mission, and provide the spectral and temporal context in the traditional 10 keV to 25 MeV band for the high energy observations by the Large Area Telescope (LAT). The GBM will use traditional rate triggers in up to three energy bands, and on a variety of timescales between 16 ...
Band, D.   +4 more
openaire   +2 more sources

PWRN1 Suppressed Cancer Cell Proliferation and Migration in Glioblastoma by Inversely Regulating hsa-miR-21-5p

open access: yesCancer Management and Research, 2020
Jianxin Jiang,* Xiaolin Wang,* Jun Lu Department of Neurosurgery, Taizhou People’s Hospital, Taizhou, Jiangsu Province 225300, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun LuDepartment of ...
Jiang J, Wang X, Lu J
doaj  

Dual role of ARPC1B in regulating the network between tumor-associated macrophages and tumor cells in glioblastoma

open access: yesOncoImmunology, 2022
The tumor microenvironment (TME) plays a critical role in promoting the growth and metastasis of glioblastoma (GBM). Tumor-associated macrophages (TAMs), the most abundant myeloid cells infiltrating in TME, produce proinflammatory cytokines, regulate ...
Tianqi Liu   +10 more
doaj   +1 more source

GRB 110709A, 111117A and 120107A: Faint high-energy gamma-ray photon emission from Fermi/LAT observations and demographic implications [PDF]

open access: yes, 2012
Launched on June 11, 2008, the LAT instrument onboard the $Fermi$ Gamma-ray Space Telescope has provided a rare opportunity to study high energy photon emission from gamma-ray bursts. Although the majority of such events (27) have been iden tified by the
Abdo   +30 more
core   +2 more sources

Repairing the GBM Step by Step [PDF]

open access: yesJournal of the American Society of Nephrology, 2018
The glomerular basement membrane (GBM) lies between the glomerular endothelium and the podocyte foot processes. In conjunction with the slit diaphragm, GBM constitutes the glomerular filtration barrier that prevents proteinuria.[1][1] The GBM’s major components in the mature kidney are ...
openaire   +2 more sources

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

open access: yesOncoImmunology, 2018
The use of inhibitory checkpoint blockade in the management of glioblastoma has been studied in both preclinical and clinical settings. TIGIT is a novel checkpoint inhibitor recently discovered to play a role in cancer immunity.
Alice L. Hung   +22 more
doaj   +1 more source

Insight into the Progress in CAR-T Cell Therapy and Combination with Other Therapies for Glioblastoma

open access: yesInternational Journal of General Medicine, 2023
Tingyu Liang,* Yixuan Song,* Lingui Gu, Yu Wang, Wenbin Ma Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China*These ...
Liang T, Song Y, Gu L, Wang Y, Ma W
doaj  

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