Results 31 to 40 of about 204,238 (313)

Co-injection of anti-HS antibodies in anti-GBM-induced glomerulonephritis differentially affects glomerular PMN and macrophage influx.

, 2021
Glomerular PMN influx after (A) 2 hours, (B) 1 day and (C) 4 days, and glomerular macrophage influx after (D) 2 hours, (E) 1 day and (F) 4 days analyzed by immunofluorescence staining. Results are expressed as means ± s.e.m. from four mice in each group.
Toin H. van Kuppevelt (10013111), Nathalie J. H. G. Passmann (11873757), Markus A. Loeven (3368984), Jasper J. van Gemst (3368987), Bart Smeets (170582), Johan van der Vlag (45996), Jo H. Berden (11873763), Ton J. Rabelink (8695392), Angelique L. W. M. M. Rops (11873760)   +8 more
core   +1 more source

The bicentenary of Georg Hartung, a German pioneer geologist, explorer, and illustrator [PDF]

History of Geo- and Space Sciences, 2021
We present a tribute to Georg Friedrich Karl Hartung (1821–1891), a less-known, non-academic German geologist, on his 200th birthday anniversary. Influenced by eminent 19th century scientific personalities, such as Oswald Heer, Charles Lyell, and ...
C. A. Góis-Marques, C. A. Góis-Marques, M. Menezes de Sequeira, M. Menezes de Sequeira, J. Madeira, J. Madeira   +5 more
doaj   +1 more source

PGE₂ Is Crucial for the Generation of FAST Whole- Tumor-Antigens Loaded Dendritic Cells Suitable for Immunotherapy in Glioblastoma

Pharmaceutics, 2020
Dendritic cells (DC) are the most potent antigen-presenting cells, strongly inducers of T cell-mediated immune responses and, as such, broadly used as vaccine adjuvant in experimental clinical settings.
Sara Nava, Daniela Lisini, Simona Frigerio, Simona Pogliani, Serena Pellegatta, Laura Gatti, Gaetano Finocchiaro, Anna Bersano, Eugenio Agostino Parati   +8 more
doaj   +1 more source

The Fermi-GBM Gamma-Ray Burst Catalogs: The First Six Years [PDF]

, 2017
Since its launch in 2008, the Fermi Gamma-ray Burst Monitor (GBM) has triggered and located on average approximately two gamma-ray bursts (GRBs) every three days.
H.-F. Yu, E. Bissaldi, Yu, H., BISSALDI, Elisabetta, Bhat, P., Bhat, P. N., P. N. Bhat, Bissaldi, E., Yu, H. F.   +8 more
core   +1 more source

Identifying a Csmd3⁺ Microglial Subpopulation that Drives Cold-to-Hot Transition and Immune-Cure in Glioblastoma. [PDF]

Adv Sci (Weinh)
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Jiang HF, Gao PP, Du YW, Wu LQ, Yin EZ, An Q, Ding ZH, Shi JW, Shu Y, Chen R, Liu F, Li M, Chen XQ.   +12 more
europepmc   +2 more sources

Glioblastoma multiforme - case presentation and literature review

Journal of Education, Health and Sport, 2019
Glioblastoma multiforme is a most common primary brain tumor with extreme malignancy index. Presented case of 75y.o. patient diagnosed with GBM underwent full treatment : surgery and adjuvant proton-therapy.
Jakub Litak, Joanna Litak, Wojciech Czyżewski, Paulina Miziak   +3 more
doaj   +1 more source

Fully automatic GBM segmentation in the TCGA-GBM dataset: Prognosis and correlation with VASARI features. [PDF]

, 2015
Reproducible definition and quantification of imaging biomarkers is essential. We evaluated a fully automatic MR-based segmentation method by comparing it to manually defined sub-volumes by experienced radiologists in the TCGA-GBM dataset, in terms of ...
Dunn, William D, Rios Velazquez, Emmanuel, Aerts, Hugo, Meier, Raphael, Dunn Jr, William D., Wiest, Roland, Reyes, Mauricio, Aerts, Hugo J W L, Gutman, David A., Alexander, Brian, Bauer, Stefan, Gutman, David A   +11 more
core   +2 more sources

Efficacy and Safety of Actively Personalized Neoantigen Vaccination in the Management of Newly Diagnosed Glioblastoma: A Systematic Review

International Journal of General Medicine, 2021
Muhammad Khan,1,2 Xianming Li,1 Maosheng Yan,1 Zihuang Li,1 Hongli Yang,1 Guixiang Liao1 1Department of Oncology, Shenzhen People’s Hospital, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, 518020, People’s ...
Khan M, Li X, Yan M, Li Z, Yang H, Liao G   +5 more
doaj  

Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth

Open Life Sciences, 2023
Glioblastoma (GBM) is a malignant brain tumor. The purpose of this study is to estimate the potential effects and underlying mechanisms of a ubiquitin-specific protease 8 (USP8) small-molecule inhibitor on the phenotypic characteristics of GBM cells. The
Long Yu, Hu Zengchun, Yang Dian, Wang Fuqiang, Zhao Chen’ge, Zhang Yang, Zhang Yingqiu, Ma Hui, Lv Huiyi   +8 more
doaj   +1 more source

mRNA expression of pro-inflammatory mediators is increased after co-injection of anti-HS antibody EW3D10 in anti-GBM-induced glomerulonephritis.

, 2021
mRNA expression of (A) IL-6, (B) CXCL1, (C) ICAM-1, (D) L-selectin, (E) NF-ĸB, (F) CD11b in renal cortex from anti-GBM IgG- or EW3D10-co-injected mice after 2 hours, 1 day and 4 days. Graphs show the relative mRNA expression in experimental mice compared
Toin H. van Kuppevelt (10013111), Nathalie J. H. G. Passmann (11873757), Markus A. Loeven (3368984), Jasper J. van Gemst (3368987), Bart Smeets (170582), Johan van der Vlag (45996), Jo H. Berden (11873763), Ton J. Rabelink (8695392), Angelique L. W. M. M. Rops (11873760)   +8 more
core   +1 more source