Results 21 to 30 of about 233,509 (250)

Fermi GBM GRBs' multivariate statistics [PDF]

Astronomische Nachrichten, 2018
Studying their gamma‐ray spectra may reveal some physical information on γ‐ray bursts (GRBs). The Fermi satellite has observed more than 2,000 GRBs. The FERMIGBRST catalog contains the GRB parameters (peak energy, spectral indices, intensity) estimated for both the total emission (fluence) and the emission during the interval of the peak flux. We found
Racz, Istvan I., Balázs, Lajos G., Bagoly, Zsolt, Horvath, Istvan, Tóth, L. Viktor   +4 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Proposal to Localize Fermi GBM GRBs Through Coordinated Scanning of the GBM Error Circle via Optical Telescopes [PDF]

, 2011
We investigate the feasibility of implementing a system that will coordinate ground-based optical telescopes to cover the Fermi GBM Error Circle (EC). The aim of the system is to localize GBM detected GRBs and facilitate multi-wavelength follow-up from ...
Abeysekara, A. U., Bhat, P. N., Gehrels, N., Linnemann, J. T., Sonbas, E., Tollefson, K., Ukwatta, T. N.   +6 more
core   +2 more sources

Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor. [PDF]

, 2017
BackgroundAlthough the contrast-enhancing (CE) lesion on T1-weighted MR images is widely used as a surrogate for glioblastoma (GBM), there are also non-enhancing regions of infiltrative tumor within the T2-weighted lesion, which elude radiologic ...
Autry, Adam, Cha, Soonmee, Chang, Susan M, Lupo, Janine M, Maleschlijski, Stojan, Molinaro, Annette M, Nelson, Sarah J, Phillips, Joanna J, Roy, Ritu   +8 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Earth Occultation Imaging of the Low Energy Gamma-Ray Sky with GBM

, 2014
The Earth Occultation Technique (EOT) has been applied to Fermi's Gamma-ray Burst Monitor (GBM) to perform all-sky monitoring for a predetermined catalog of hard X-ray/soft gamma-ray sources.
Camero-Arranz, A., Case, G. L., Chaplin, V., Cherry, M. L., Finger, M. H., Jenke, P., Rodi, J., Wilson-Hodge, C. A.   +7 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The Interplanetary Network Supplement to the Fermi GBM Catalog of Cosmic Gamma-Ray Bursts

, 2013
We present Interplanetary Network (IPN) data for the gamma-ray bursts in the first Fermi Gamma-Ray Burst Monitor (GBM) catalog. Of the 491 bursts in that catalog, covering 2008 July 12 to 2010 July 11, 427 were observed by at least one other instrument ...
Aptekar, R. L., Barthelmy, S., Boynton, W., Briggs, M. S., Cline, T., Connaughton, V., Cummings, J., Del Monte, E., Fellows, C., Feroci, M., Frederiks, D. D., Fukazawa, Y., Gehrels, N., Goldsten, J., Golenetskii, S. V., Golovin, D. V., Hanabata, Y., Harshman, K., Hurley, K., Kozyrev, A. S., Krimm, H. A., Litvak, M. L., Makishima, K., Marisaldi, M., Mazets, E. P., Meegan, C., Mitrofanov, I. G., Murakami, T., Ohno, M., Pal'shin, V. D., Rau, A., Sanin, A. B., Smith, D. M., Svinkin, D. S., Takahashi, T., Tashiro, M., Terada, Y., von Kienlin, A., Yamaoka, K., Zhang, X.   +39 more
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +15 more
wiley   +1 more source

Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas. [PDF]

, 2019
PurposeGlioblastoma (GBM) remains an incurable disease despite extensive treatment with surgical resection, irradiation, and temozolomide. In line with many other forms of aggressive cancers, GBM is currently under consideration as a target for ...
Kaprealian, Tania, Lee, Mi-Heon, McBride, William H, Nesseler, Jean Philippe, Nickers, Philippe, Niclou, Simone P, Schaue, Dorthe   +6 more
core