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Approaches to PET Imaging of Glioblastoma
Molecules, 2020 Glioblastoma multiforme (GBM) is the deadliest type of brain tumor, affecting approximately three in 100,000 adults annually. Positron emission tomography (PET) imaging provides an important non-invasive method of measuring biochemically specific targets
Lindsey R. Drake +2 more
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Cancer Medicine, 2023 Glioblastoma Multiforme (GBM) remains the most common malignant primary brain tumor with a dismal prognosis that rarely exceeds beyond 2 years despite extensive therapy, which consists of maximal safe surgical resection, radiotherapy, and/or chemotherapy.
B. Decraene +9 more
doaj +1 more source
The role of checkpoints in the treatment of GBM [PDF]
Journal of Neuro-Oncology, 2015 Targeted immunotherapy is founded on the principle that augmentation of effector T cell activity in the tumor microenvironment can translate to tumor regression. Targeted checkpoint inhibitors in the form of agonist or antagonist monoclonal antibodies have come to the fore as a promising strategy to activate systemic immunity and enhance T cell ...
Jennifer E, Kim, Michael, Lim
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Analysis of sentiments on the onset of Covid-19 using Machine Learning Techniques
Advances in Distributed Computing and Artificial Intelligence Journal, 2022 The novel coronavirus (Covid-19) pandemic has struck the whole world and is one of the most striking topics on social media platforms. Sentiment outbreak on social media enduring various thoughts, opinions, and emotions about the Covid-19 disease ...
Vishakha Arya +2 more
doaj +1 more source
Therapeutic approach in glioblastoma multiforme with primitive neuroectodermal tumor components: case report and review of the literature [PDF]
, 2018 Glioblastoma multiforme (GBM) is the most common and aggressive malignant glioma that is treated with first-line therapy, using surgical resection followed by local radiotherapy and concomitant/adjuvant temozolomide (TMZ) treatment.
Berrios J. R. G. +12 more
core +1 more source
Renal Failure, 2020 Objective Autoantibodies to the α3 chain noncollagen 1 domain of type IV collagen (α3(IV)NC1) are a serological hallmark in the diagnosis of anti-glomerular basement membrane (GBM) disease.
Ying Tan +3 more
doaj +1 more source
Dexamethasone in glioblastoma multiforme therapy : mechanisms and controversies [PDF]
, 2019 Glioblastoma multiforme (GBM) is the most common and malignant of the glial tumors. The world-wide estimates of new cases and deaths annually are remarkable, making GBM a crucial public health issue.
Luigi Sforna +8 more
core +2 more sources
Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors [PDF]
, 2018 Background Reprogramming of cancers into normal-like tissues is an innovative strategy for cancer treatment. Recent reports demonstrate that defined factors can reprogram cancer cells into pluripotent stem cells. Glioblastoma multiforme (GBM) is the most
Hallahan, Dennis +7 more
core +2 more sources
Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. [PDF]
, 2016 Natural killer (NK) cells are functionally suppressed in the glioblastoma multiforme (GBM) tumor microenvironment. We have recently shown that survival and differentiation of cancer stem-like cells (CSCs)/poorly differentiated tumors are controlled ...
Bui, Vickie T +8 more
core +1 more source
Advances in nanotechnology for the treatment of GBM
Frontiers in Neuroscience, 2023 Glioblastoma (GBM), a highly malignant glioma of the central nervous system, is the most dread and common brain tumor with a high rate of therapeutic resistance and recurrence. Currently, the clinical treatment methods are surgery, radiotherapy, and chemotherapy. However, owning to the highly invasive nature of GBM, it is difficult to completely resect
Dongyan Wei +5 more
openaire +3 more sources