Results 71 to 80 of about 204,238 (313)
Comparative analyses of gene copy number and mRNA expression in GBM tumors and GBM xenografts [PDF]
, 2009 Development of model systems that recapitulate the molecular heterogeneity observed among glioblastoma multiforme (GBM) tumors will expedite the testing of targeted molecular therapeutic strategies for GBM treatment.
James, C. David +13 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2022 Glioblastoma (GBM) is one of the most prevalent and aggressive cancers worldwide. The overall survival period of GBM patients is only 15 months even with standard combination therapy.
Kun Liu +5 more
doaj +1 more source
AIP Conference Proceedings, 2004 The GLAST Burst Monitor (GBM) will detect and localize bursts for the GLAST mission, and provide the spectral and temporal context in the traditional 10 keV to 25 MeV band for the high energy observations by the Large Area Telescope (LAT). The GBM will use traditional rate triggers in up to three energy bands, and on a variety of timescales between 16 ...
Band, D. +4 more
openaire +2 more sources
Chromatin state model for epigenetic marks in GBM tumors
, 2018 Chromatin state model based on CTCF transcription factor marks and H3K27Ac, H3K27Me3, H3K4Me1, H3K4Me3, H3K9Ac, and H3K9Me3 histone modifications in 11 primary GBM tumors, produced by ChromHMM from binarized significant ChIP-seq peaks.
Hall, Amelia Weber
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Acta Neuropathologica Communications, 2021 Short survival of glioblastoma (GBM) patients is due to systematic tumor recurrence. Our laboratory identified a GBM cell subpopulation able to leave the tumor mass (TM) and invade the subventricular zone (SVZ-GBM cells).
Marina Digregorio +5 more
doaj +1 more source
ChIP-seq peak calls for epigenetic marks in GBM tumors
, 2018 MACS2 narrowPeak files from ChIP-seq experiments for 11 primary GBM tumors, each targeting CTCF transcription factor marks and H3K27Ac, H3K27Me3, H3K4Me1, H3K4Me3, H3K9Ac, and H3K9Me3 histone modifications.
Battenhouse, Anna, Hall, Amelia Weber
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source
Advanced Functional Materials, EarlyView.Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro +25 more
wiley +1 more source