Results 81 to 90 of about 204,238 (313)

RNA-seq whole-genome signal for GBM tumors and cell lines

open access: yes, 2018
Whole-genome RNA-seq signal per million reads for primary GBM tumors and cell lines, as hg38 bigWig track files produced from Tophat2-aligned BAMs.
Battenhouse, Anna, Hall, Amelia Weber
core   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

open access: yesAdvanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake   +5 more
wiley   +1 more source

LncRNA SLC16A1-AS1 is Upregulated in Glioblastoma and Promotes Cancer Cell Proliferation by Regulating miR-149 Methylation

open access: yesCancer Management and Research, 2021
Yinbo Long, Heyang Li, Zhibin Jin, Xiang Zhang Department of Neurosurgery, Cangzhou Central Hospital, Cangzhou City, Hebei Province, 061000, People’s Republic of ChinaCorrespondence: Xiang ZhangDepartment of Neurosurgery, Cangzhou Central Hospital,
Long Y, Li H, Jin Z, Zhang X
doaj  

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

ChIP-seq whole-genome signal for epigenetic marks in GBM tumors

open access: yes, 2018
Whole-genome GBM tumor ChIP-seq signal on hg38, input-corrected and normalized for sequencing depth, from MACS2 callpeak and bdgcmp commands used to produce signal track bigWig files.
Battenhouse, Anna, Hall, Amelia Weber
core   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

open access: yesAdvanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz   +5 more
wiley   +1 more source

Dissecting Prognosis Modules and Biomarkers in Glioblastoma Based on Weighted Gene Co-Expression Network Analysis

open access: yesCancer Management and Research, 2021
Fang Cao,1,* Yinchun Fan,1,* Yunhu Yu,2 Guohua Yang,3 Hua Zhong4 1Department of Cerebrovascular Disease, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563000, People’s Republic of China; 2Clinical Research Center for ...
Cao F, Fan Y, Yu Y, Yang G, Zhong H
doaj  

Emerging Role of Tumor-associated Macrophages as Therapeutic Targets in Glioblastoma Multiforme

open access: yesNano Biomedicine and Engineering, 2014
The most common types of primary brain tumors in adults are gliomas. Glioblastoma multiforme (GBM) is the most highly aggressive type of glioma. GBM contains various numbers of cells with characteristics of activated or dysmorphic macrophages/microglia ...
Xian-Bin Lin   +3 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy