Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Usman M +4 more
europepmc +1 more source
Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis +7 more
wiley +1 more source
VOC Emission Screening of Consumer Products in Microchambers: Comparison of Online PTR-MS and Offline TD-GC-MS Analysis. [PDF]
Klein L +4 more
europepmc +1 more source
Here, we present a textile, wearable capacitive interface enabling multidirectional remote control by dynamically modulating electrode overlap and spacing via a freely gliding upper electrode. A forearm‐mounted prototype drives robotic and media tasks with 12–15 ms latency, maintains < 0.8% drift after 500 cycles, and remains stably functional at 90 ...
Cagatay Gumus +8 more
wiley +1 more source
First Application of QuEChERS-GC-MS Analysis for Polycyclic Aromatic Hydrocarbons Detection in Human Adipose Tissue. [PDF]
Franchin A +9 more
europepmc +1 more source
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su +10 more
wiley +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Gas Chromatography-Mass Spectrometry (GC-MS) in the Plant Metabolomics Toolbox: Sample Preparation and Instrumental Analysis. [PDF]
Frolova N +4 more
europepmc +1 more source
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source

