Results 1 to 10 of about 4,416 (128)
A transcription factor glial cell missing (Gcm) in the freshwater crayfish Pacifastacus leniusculus
Developmental & Comparative Immunology, 2020 The transcription factor glial cell missing, Gcm, is known to be an important protein in the determination of glial cell fate as well as embryonic plasmatocyte differentiation in Drosophila melanogaster. So far, no function for Gcm in crustaceans has been reported.
Kingkamon Junkunlo +2 more
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Revisiting the role of the Gcm transcription factor, from master regulator to Swiss army knife [PDF]
Fly, 2016 Master genes are known to induce the differentiation of a multipotent cell into a specific cell type. These molecules are often transcription factors that switch on the regulatory cascade that triggers cell specification. Gcm was first described as the master gene of the glial fate in Drosophila as it induces the differentiation of neuroblasts into ...
Pierre B. Cattenoz, Angela Giangrande
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Neurogenic role of Gcm transcription factors is conserved in chicken spinal cord [PDF]
Development, 2007 Although glial cells missing (gcm) genes are known as glial determinants in the fly embryo, the role of vertebrate orthologs in the central nervous system is still under debate. Here we show for the first time that the chicken ortholog of fly gcm (herein referred to as c-Gcm1), is expressed in early neuronal lineages of the developing spinal cord and ...
Laurent Soustelle +6 more
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Scientific Reports, 2016 AbstractNR5A1 is essential for the development and for the function of steroid producing glands of the reproductive system. Moreover, its misregulation is associated with endometriosis, which is the first cause of infertility in women. Hr39, the Drosophila ortholog of NR5A1, is expressed and required in the secretory cells of the spermatheca, the ...
Pierre B. Cattenoz +3 more
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Biochemical Journal, 2012 NAC (NAM/ATAF/CUC) plant transcription factors regulate essential processes in development, stress responses and nutrient distribution in important crop and model plants (rice, Populus, Arabidopsis), which makes them highly relevant in the context of crop optimization and bioenergy production.
Ditte Hededam Welner +7 more
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Analysis of cnidarian Gcm suggests a neuronal origin of glial EAAT1 function [PDF]
Scientific Reports, 2023 In bilaterian central nervous systems, coordination of neurotransmission by glial cells enables highly sophisticated neural functions. The diversity of transcription factors (TFs) involved in gliogenesis suggests multiple evolutionary origins of various ...
Larisa Sheloukhova, Hiroshi Watanabe
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Scorpion (Hottentotta tamulus) venom pre-exposure delays functional recovery in mice following peripheral nerve injury. [PDF]
PLoS ONEScorpion sting leads to profound challenges of central nervous system (CNS) impairments such as neuro-inflammation, unconsciousness, aberrant ion channels physiology, epilepsy and may become fatal due to heart failure.
Abbas Khan +5 more
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Polycomb controls gliogenesis by regulating the transient expression of the Gcm/Glide fate determinant. [PDF]
PLoS Genetics, 2012 The Gcm/Glide transcription factor is transiently expressed and required in the Drosophila nervous system. Threshold Gcm/Glide levels control the glial versus neuronal fate choice, and its perdurance triggers excessive gliogenesis, showing that its tight
Anna Popkova +8 more
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Horticulturae, 2023 Broccoli (Brassica oleracea L. var. italica) has a large, edible green flower head, which is one of its critical economic traits. A prerequisite of broccoli flower head formation is flower bud differentiation (FBD).
Wenchen Chai +10 more
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Embryonic hematopoiesis modulates the inflammatory response and larval hematopoiesis in Drosophila
eLife, 2018 Recent lineage tracing analyses have significantly improved our understanding of immune system development and highlighted the importance of the different hematopoietic waves.
Wael Bazzi +6 more
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