Results 151 to 160 of about 521,325 (180)
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Specification of Drosophila hematopoietic lineage by conserved transcription factors.
Science, 2000Two major classes of cells observed within the Drosophila hematopoietic repertoire are plasmatocytes/macrophages and crystal cells. The transcription factor Lz (Lozenge), which resembles human AML1 (acute myeloid leukemia- 1) protein, is necessary for ...
T. Lebestky +3 more
semanticscholar +1 more source
Transcription factors in the development and treatment of immune disorders
Transcription, 2023Immune function is highly controlled at the transcriptional level by the binding of transcription factors (TFs) to promoter and enhancer elements. Several TF families play major roles in immune gene expression, including NF-κB, STAT, IRF, AP-1, NRs, and ...
Samantha D Patalano +2 more
semanticscholar +1 more source
Targeting transcription factors in cancer — from undruggable to reality
Nature Reviews Cancer, 2019 John H Bushweller
exaly +2 more sources
Targeting bacterial transcription factors for infection control: opportunities and challenges
Transcription, 2023The rising threat of antibiotic resistance in pathogenic bacteria emphasizes the need for new therapeutic strategies. This review focuses on bacterial transcription factors (TFs), which play crucial roles in bacterial pathogenesis.
Ahmed Al-Tohamy, A. Grove
semanticscholar +1 more source
Biochemical characterization of the human placental transcription factor GCMa/1.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 2005Glial cells missing (GCM) proteins are a novel family of zinc-containing transcription factors. Human GCMa/1 is primarily expressed in placental trophoblast cells and regulates SYNCYTIN gene expression, which mediates fusion of cytotrophoblasts to form ...
Chenchen Lin, Meiyao Lin, Hungwen Chen
semanticscholar +1 more source
Biochemical and Biophysical Research Communications - BBRC, 2000
The genomic sequence of the human GCMa/GCM1 gene, a mammalian homologue of Drosophila melanogaster GCM, was determined. Drosophila GCM is a neural transcription factor that regulates glial cell fate.
K. Yamada +7 more
semanticscholar +1 more source
The genomic sequence of the human GCMa/GCM1 gene, a mammalian homologue of Drosophila melanogaster GCM, was determined. Drosophila GCM is a neural transcription factor that regulates glial cell fate.
K. Yamada +7 more
semanticscholar +1 more source
Transcription
Hypoxia-inducible factors (HIFs) play a pivotal role as master regulators of tumor survival and growth, controlling a wide array of cellular processes in response to hypoxic stress.
Alexander McDermott, Ali Tavassoli
semanticscholar +1 more source
Hypoxia-inducible factors (HIFs) play a pivotal role as master regulators of tumor survival and growth, controlling a wide array of cellular processes in response to hypoxic stress.
Alexander McDermott, Ali Tavassoli
semanticscholar +1 more source
Bulletin of experimental biology and medicine, 2022
V. A. Gusar +5 more
semanticscholar +1 more source
V. A. Gusar +5 more
semanticscholar +1 more source