The placental transcription factors Distal-less 3 (DLX3) and Glial cell missing-1 (GCM1) have been shown to coordinate the specific regulation of PGF in human trophoblast cell lines.
Sha Li, Mark S. Roberson
doaj +2 more sources
Placental Failure in Mice Lacking the Mammalian Homolog of Glial Cells Missing, GCMa [PDF]
The GCM family of transcription factors consists of Drosophila melanogaster GCM, an important regulator of gliogenesis in the fly, and its two mammalian homologs, GCMa and GCMb.
Riethmacher-Sonnenberg, Eva
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Embryonic hematopoiesis modulates the inflammatory response and larval hematopoiesis in Drosophila
Recent lineage tracing analyses have significantly improved our understanding of immune system development and highlighted the importance of the different hematopoietic waves.
Wael Bazzi+6 more
doaj +1 more source
Genomic control of patterning [PDF]
The development of multicellular organisms involves the partitioning of the organism into territories of cells of specific structure and function. The information for spatial patterning processes is directly encoded in the genome.
Davidson, Eric H., Peter, Isabelle S.
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Gcm proteins function in the developing nervous system [PDF]
A fundamental issue during nervous system development is how individual cells are formed from the undefined precursors. Differentiated neurons and glia, two major cell types mediating neuronal function, are acquired from immature precursors via a series ...
Mao, Haian+2 more
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Evolutionary plasticity of developmental gene regulatory network architecture [PDF]
Sea stars and sea urchins evolved from a last common ancestor that lived at the end of the Cambrian, approximately half a billion years ago. In a previous comparative study of the gene regulatory networks (GRNs) that embody the genomic program for ...
Britten+25 more
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Drosophila GATA Factor Serpent Establishes Phagocytic Ability of Embryonic Macrophages
During Drosophila embryogenesis, a large number of apoptotic cells are efficiently engulfed and degraded by professional phagocytes, macrophages. Phagocytic receptors Six-Microns-Under (SIMU), Draper (Drpr) and Croquemort (Crq) are specifically expressed
Evgeny Shlyakhover+5 more
doaj +1 more source
Isolation of pigment cell specific genes in the sea urchin embryo by differential macroarray screening [PDF]
New secondary mesenchyme specific genes, expressed exclusively in pigment cells, were isolated from sea urchin embryos using a differential screening of a macroarray cDNA library. The comparison was performed between mRNA populations of embryos having an
Calestani, Cristina+2 more
core +1 more source
glial cells missing and gcm2 Cell Autonomously Regulate Both Glial and Neuronal Development in the Visual System of Drosophila [PDF]
SummaryThe transcription factors Glial cells missing (Gcm) and Gcm2 are known to play a crucial role in promoting glial-cell differentiation during Drosophila embryogenesis.
Chotard, Carole+2 more
core +1 more source
Properties of developmental gene regulatory networks [PDF]
The modular components, or subcircuits, of developmental gene regulatory networks (GRNs) execute specific developmental functions, such as the specification of cell identity.
Davidson, Eric H., Levine, Michael S.
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