Results 21 to 30 of about 521,325 (180)

The hypoparathyroidism-associated mutation in Drosophila Gcm compromises protein stability and glial cell formation

open access: yesScientific Reports, 2017
Differentiated neurons and glia are acquired from immature precursors via transcriptional controls exerted by factors such as proteins in the family of Glial Cells Missing (Gcm).
Xiao Xi   +11 more
semanticscholar   +1 more source

CXCL16/CXCR6 axis drives microglia/macrophages phenotype in physiological conditions and plays a crucial role in glioma [PDF]

open access: yes, 2018
Microglia are patrolling cells that sense changes in the brain microenvironment and respond acquiring distinct phenotypes that can be either beneficial or detrimental for brain homeostasis.
Antonangeli, Fabrizio   +6 more
core   +1 more source

Enhanced osteoprogenitor elongated collagen fiber matrix formation by bioactive glass ionic silicon dependent on Sp7 (osterix) transcription.

open access: yesJournal of Biomedical Materials Research. Part A, 2016
Bioactive glasses release ions, those enhance osteoblast collagen matrix synthesis and osteogenic marker expression during bone healing. Collagen matrix density and osteogenic marker expression depend on osteogenic transcription factors, (e.g., Osterix ...
V. Varanasi   +5 more
semanticscholar   +1 more source

Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo [PDF]

open access: yes, 2008
We dissect the transcriptional regulatory relationships coordinating the dynamic expression patterns of two signaling genes, wnt8 and delta, which are central to specification of the sea urchin embryo endomesoderm.
Alifragis   +34 more
core   +3 more sources

Diversification of oral and aboral mesodermal regulatory states in pregastrular sea urchin embryos [PDF]

open access: yes, 2013
Specification of the non-skeletogenic mesoderm (NSM) in sea urchin embryos depends on Delta signaling. Signal reception leads to expression of regulatory genes that later contribute to the aboral NSM regulatory state.
Davidson, Eric H.   +3 more
core   +1 more source

Logic of gene regulatory networks [PDF]

open access: yes, 2007
Regulatory networks of transcription factors and signaling molecules lie at the heart of development. Their architecture implements logic functions whose execution propels cells from one regulatory state to the next, thus driving development forward.
Davidson, Eric H., Materna, Stefan C.
core   +2 more sources

Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria

open access: yesAngewandte Chemie, Volume 137, Issue 25, June 17, 2025.
A structurally distinct glycopeptide, saarvienin A, represents a new family of glycopeptide antibiotics consisting of five sugar/aminosugar units connected to a halogenated peptide core. Saarvienin A overcomes vancomycin resistance and shows strong activity against drug‐resistant Gram‐positive bacteria, in particular, high‐priority pathogens such as ...
Amninder Kaur   +7 more
wiley   +2 more sources

Structural requirements for DNA binding of GCM proteins.

open access: yesNucleic Acids Research, 1998
Members of the GCM family of transcription factors contain a DNA binding domain unrelated to any other known DNA binding domain and bind to a DNA sequence motif not recognized by any other known transcription factor.
J. Schreiber, Janna Enderich, M. Wegner
semanticscholar   +1 more source

The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage [PDF]

open access: yes, 2009
As the result of early specification processes, sea urchin embryos eventually form various mesodermal cell lineages and a gut consisting of fore-, mid- and hindgut.
Davidson, Eric H., Peter, Isabelle S.
core   +1 more source

eyeless/Pax6 controls the production of glial cells in the visual center of Drosophila melanogaster [PDF]

open access: yes, 2016
Pax6 is known as a neurogenic factor in the development of the central nervous system and regulates proliferation of neuronal progenitor cells and promotes neuronal differentiation.
Sato, Makoto   +2 more
core   +1 more source

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