Results 41 to 50 of about 4,419 (127)

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy   +4 more
wiley   +1 more source

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids [PDF]

open access: yes, 2018
Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks change to control novel developmental phenotypes remains, in most cases, unresolved. Here, we address GRN evolution by comparing the
Davidson, Eric H.   +2 more
core   +1 more source

Evidence suggesting that di-n-butyl phthalate has anti-androgenic effects in fish [PDF]

open access: yes, 2011
This article is the pre-print version of the full and final published article.Phthalate ester plasticizers are anti-androgenic in mammals. High doses of certain phthalates consistently interfere with the normal development of male offspring exposed in ...
Adams   +39 more
core   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

open access: yesAndrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell   +12 more
wiley   +1 more source

Bridging the gap between omics and earth system science to better understand how environmental change impacts marine microbes [PDF]

open access: yes, 2015
The advent of genomic-, transcriptomic- and proteomic-based approaches has revolutionized our ability to describe marine microbial communities, including biogeography, metabolic potential and diversity, mechanisms of adaptation, and phylogeny and ...
Alexander   +129 more
core   +1 more source

Assessment of Leishmania exposure in blood donors from a non‐endemic urban area: A study in São Paulo

open access: yesVox Sanguinis, Volume 121, Issue 2, Page 160-168, February 2026.
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima   +14 more
wiley   +1 more source

Developmental gene network analysis [PDF]

open access: yes, 2003
The developmental process is controlled by the information processing functions executed by the cis-elements that regulate the expression of the participating genes.
Davidson, Eric H.   +1 more
core  

Dyson-Schwinger Equations and the Application to Hadronic Physics

open access: yes, 1994
We review the current status of nonperturbative studies of gauge field theory using the Dyson-Schwinger equation formalism and its application to hadronic physics. We begin with an introduction to the formalism and a discussion of renormalisation in this
Alkofer   +198 more
core   +1 more source

Ablation of neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression [PDF]

open access: yes, 2016
Gliomas are the most commonly diagnosed primary tumors of the central nervous system (CNS). Median times of survival are dismal regardless of the treatment approach, underlying the need to develop more effective therapies. Modulation of the immune system
Chen, D   +8 more
core   +2 more sources

Targeting the Spinal Cord‐Brain Axis: Electroacupuncture Mitigates Remote Frontal Cortex Neuroinflammation via HMGB1/TLR4 to Aid Functional Recovery After Spinal Cord Injury

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
Spinal cord injury (SCI) has been shown to trigger remote neuroinflammation in the frontal cortex via the HMGB1/TLR4/NF‐κB pathway, exacerbating neural damage and impairing functional recovery. The present study demonstrates that electroacupuncture (EA) at GV4 (Mingmen) and GV14 (Dazhui) effectively mitigates this pathological cascade.
Yu Ning   +9 more
wiley   +1 more source

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