Results 51 to 60 of about 521,325 (180)

Characterization of Cis-Regulatory Elements Controlling Repo Transcription in Drosophila Melanogaster [PDF]

, 2011
The glial cells missing (gcm) gene has been identified as a master regulator of glial cell fate in the fruit fly Drosophila . However, the gcm gene is also expressed in and required for the development of larval macrophages and tendon cells, and lamina
Johnson, Robert
core   +1 more source

The performance of different methods in characterizing soil live prokaryotic diversity and abundance is highly variable

iMetaOmics, Volume 2, Issue 2, June 2025.
We systematically compared and assessed the commonly used methods for studying live soil microbes, including alkaline buffer washing, propidium monoazide (PMA) treatment, DNase pre‐digestion, and rRNA‐based analysis, based on soils collected across the western region of China.
Yuan Du, Zelin Wang, Kaifang Liu, Guanyu Chai, Yuan Chi, Ting Li, Yi Duan, Tianjiao Xia, Dong Liu, Rongxiao Che   +9 more
wiley   +1 more source

Alx1, a member of the Cart1/Alx3/Alx4 subfamily of Paired-class homeodomain proteins, is an essential component of the gene network controlling skeletogenic fate specification in the sea urchin embryo [PDF]

, 2003
In the sea urchin embryo, the large micromeres and their progeny function as a critical signaling center and execute a complex morphogenetic program.
De Jong, Deborah L., Ettensohn, Charles A., Illies, Michele R., Oliveri, Paola   +3 more
core   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

iMeta, Volume 4, Issue 3, June 2025.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang, Rong Li, Yasong Liu, Jinliang Liang, Yihang Gong, Cuicui Xiao, Jianye Cai, Tingting Wang, Qiang You, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Yingcai Zhang, Yang Yang, Hua Li, Jia Yao, Qi Zhang, Jun Zheng   +17 more
wiley   +1 more source

Modularity and design principles in the sea urchin embryo gene regulatory network [PDF]

, 2009
The gene regulatory network (GRN) established experimentally for the pre-gastrular sea urchin embryo provides causal explanations of the biological functions required for spatial specification of embryonic regulatory states.
Amore, Barolo, Bolouri, Davidson, Davidson, Davidson, Eric H. Davidson, Evans, Geiss, Gurdon, Howard-Ashby, Howard-Ashby, Isabelle S. Peter, Kumano, Kurokawa, Logan, Mahmud, Materna, Minokawa, Nam, Oliveri, Oliveri, Oliveri, Oliveri, Otim, Owraghi, Pehrson, Range, Range, Ransick, Ransick, Ransick, Ransick, Ransick, Ransick, Revilla-i-Domingo, Rizzo, Sethi, Sherwood, Smith, Smith, Smith, Smith, Su, Sweet, Tu, Wang, Wikramanayake   +47 more
core   +1 more source

Phytochemistry, Antibacterial and Antioxidant Activities of Grewia lasiocarpa E. Mey. Ex Harv. Fungal Endophytes: A Computational and Experimental Validation Study

Chemistry &Biodiversity, Volume 22, Issue 5, May 2025.
Schematics workflow for the isolation and characterisation of endophytic fungi from grewia lasiocarpa and their biological activity. Abstract The genus Grewia are well‐known for their medicinal properties and are widely used in traditional remedies due to their rich phytochemical composition and potential health benefits.
Nneka Augustina Akwu, Yougasphree Naidoo, Moganavelli Singh, Johnson Lin, Jamiu Olaseni Aribisala, Saheed Sabiu, Makhotso Lekhooa, Adeyemi Oladapo Aremu   +7 more
wiley   +1 more source

MANF silencing, immunity induction or autophagy trigger an unusual cell type in metamorphosing Drosophila brain [PDF]

, 2014
Glia are abundant cells in the brain of animals ranging from flies to humans. They perform conserved functions not only in neural development and wiring, but also in brain homeostasis.
Heino, Tapio, Stratoulias, Vassilis
core   +1 more source

Impact of Zn‐Modified Hydroxyapatite Whiskers on Physicochemical and Biological Properties of Poly(ε‐Caprolactone) Composites Intended for Implantable Medical Devices

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 5, May 2025.
ABSTRACT Poly(ε‐caprolactone) (PCL)‐hydroxyapatite (HAP) biocomposites were produced by thermal processing to test the impact of HAP addition on the physicochemical and biological properties of PCL. Two different HAPs: zinc‐modified and unmodified, were added to the polymer matrix to enhance their biocompatibility, surface properties, and antimicrobial
Monika Biernat, Joanna Pagacz, Paweł Piszko, Małgorzata Siwińska, Emilia Zachanowicz, Sylwia Michlewska, Agnieszka Antosik, Paulina Tymowicz‐Grzyb, Anna Sylla, Piotr Szterner, Adrian Najmrodzki, Mateusz Urbaniak, Paulina Rusek‐Wala, Aleksandra Szwed‐Georgiou, Karolina Rudnicka, Konrad Szustakiewicz   +15 more
wiley   +1 more source

Characterization of transcription of genomic regions harboring HERV-W elements [PDF]

, 2014
Human endogenous retroviruses (HERV) comprise 8% of the human genome and can be classified into at least 31 families. A typical HERV provirus consists of internal gag, pol and env genes, flanked by two long terminal repeats (LTRs).
Li, Fang
core   +1 more source

Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis

FASEB BioAdvances, Volume 7, Issue 5, May 2025.
Iron deficiency and anemia are frequent complications of inflammatory bowel disease (IBD) and patients are treated with oral iron supplements. To compare the outcome of iron‐deficiency or iron‐supplementation on the severity of inflammation, wild‐type mice were fed an iron‐deficient, iron‐adequate or iron‐supplemented diet.
Thanina Medjbeur, Ugo Sardo, Prunelle Perrier, Kevin Cormier, Maryline Roy, Anne Dumay, Léon Kautz   +6 more
wiley   +1 more source