Jaborandi (Pilocarpus microphyllus) essential oil is obtained by removal and characterization using GC‐MS, revealing γ‐cadinene and trans‐caryophyllene as major constituents. The oil exhibits biological activity, with antifungal action against Candida spp.
Juniel Cruz Silva +15 more
wiley +1 more source
Alx1, a member of the Cart1/Alx3/Alx4 subfamily of Paired-class homeodomain proteins, is an essential component of the gene network controlling skeletogenic fate specification in the sea urchin embryo [PDF]
In the sea urchin embryo, the large micromeres and their progeny function as a critical signaling center and execute a complex morphogenetic program.
De Jong, Deborah L. +3 more
core +1 more source
Wheat Flour Intake Promotes Weight Gain and Metabolic Changes in Mice
When given a choice between standard chow and wheat‐based foods such as bread or baked wheat flour, mice consistently preferred the wheat products. This selective intake led to significant weight gain despite unchanged total caloric consumption. Wheat flour intake was associated with reduced energy expenditure, enhanced hepatic fatty acid synthesis ...
Shigenobu Matsumura +14 more
wiley +1 more source
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. [PDF]
International ...
Amelie Avet-Rochex +9 more
core +4 more sources
Expanding the Genetic and Phenotypic Spectrum of POLRMT‐Related Mitochondrial Disease
We identified potentially damaging monoallelic and biallelic POLRMT variants in affected individuals from six unrelated families, thus extending both the clinical and genetic phenotypes of POLRMT‐related mitochondrial disease. ABSTRACT Mitochondrial diseases are a complex group of conditions exhibiting significant phenotypic and genetic heterogeneity ...
Mahmoud R. Fassad +20 more
wiley +1 more source
A gene regulatory network controlling the embryonic specification of endoderm [PDF]
Specification of endoderm is the prerequisite for gut formation in the embryogenesis of bilaterian organisms. Modern lineage labelling studies have shown that in the sea urchin embryo model system, descendants of the veg1 and veg2 cell lineages produce ...
Davidson, Eric H., Peter, Isabelle S.
core
Parents’ views on how health professionals should work with them now to get the best for their child in the future [PDF]
Background Pregnancy and the first years of life are important times for future child well-being. Early identification of families and children who might be likely to experience poorer outcomes could enable health professionals and parents to work ...
Appleton +32 more
core +1 more source
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu +9 more
wiley +1 more source
A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity [PDF]
Previously, we discovered a conserved interaction between RB proteins and the Condensin II protein CAP-D3 that is important for ensuring uniform chromatin condensation during mitotic prophase.
AJ Nappi +93 more
core +5 more sources
This study provides the first mitogenome of the endangered Peacock Softshell Turtle (Nilssonia hurum), revealing its evolutionary relationships and moderate genetic diversity across river basins. Species distribution modeling predicts up to 85% habitat loss under future climate scenarios, alongside severe declines in functional connectivity and rising ...
Imon Abedin +7 more
wiley +1 more source

