Characterization of transcription of genomic regions harboring HERV-W elements [PDF]
Human endogenous retroviruses (HERV) comprise 8% of the human genome and can be classified into at least 31 families. A typical HERV provirus consists of internal gag, pol and env genes, flanked by two long terminal repeats (LTRs).
Li, Fang
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Radiation‐induced biological effects are an extremely complex and extensive mechanism that involves multiple aspects of physiological activities in organisms. In the medical field, utilizing the damaging effects of radiation to treat tumors is a commonly employed therapeutic approach.
Zhihe Hu +5 more
wiley +1 more source
Defective Artemis causes mild telomere dysfunction [PDF]
This article has been made available through the Brunel Open Access Publishing Fund.Background: Repair of DNA double strand breaks by non-homologous end joining (NHEJ) requires several proteins including Ku, DNA-PKcs, Artemis, XRCC4, Ligase IV and XLF ...
Slijepcevic, P, Yasaei, H
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Neurofly 2008 abstracts : the 12th European Drosophila neurobiology conference 6-10 September 2008 Wuerzburg, Germany [PDF]
This volume consists of a collection of conference ...
Buchner, Erich, Heisenberg, Martin
core
The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy [PDF]
Myocarditis is a diverse group of heart-specific immune processes classified by clinical and histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with inflammation or viral infection.
Cooper, Leslie T. +3 more
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Placental Failure in Mice Lacking the Mammalian Homolog of Glial Cells Missing, GCMa [PDF]
The GCM family of transcription factors consists of Drosophila melanogaster GCM, an important regulator of gliogenesis in the fly, and its two mammalian homologs, GCMa and GCMb.
Riethmacher-Sonnenberg, Eva
core
Autoregulation of the Glial Gene Reversed Polarity in Drosophila Melanogaster [PDF]
Autoregulation is the process where an encoded protein is able to bind to and positively or negatively regulate its own expression. Autoregulatory loops are crucial for sustained gene expression, and such loops have been demonstrated to be important for ...
Suiter, Chase
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Muscle plasticity related to changes in tubulin and αB-crystallin levels induced by eccentric contraction in rat skeletal muscles [PDF]
We used the model of eccentric contraction of the hindlimb muscle by Ochi et al. to examine the role of eccentric contraction in muscle plasticity. This model aims to focus on stimulated skeletal muscle responses by measuring tissue weights and tracing ...
Hatta, H +5 more
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HES5 silencing is an early and recurrent change in prostate tumourigenesis. [PDF]
Prostate cancer is the most common cancer in men, resulting in over 10 000 deaths/year in the UK. Sequencing and copy number analysis of primary tumours has revealed heterogeneity within tumours and an absence of recurrent founder mutations, consistent ...
Brewer, Daniel S +16 more
core +4 more sources
Robust and stable transcriptional repression in Giardia using CRISPRi. [PDF]
Giardia lamblia is a binucleate protistan parasite causing significant diarrheal disease worldwide. An inability to target Cas9 to both nuclei, combined with the lack of nonhomologous end joining and markers for positive selection, has stalled the ...
Booker, J +7 more
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