Results 71 to 80 of about 521,325 (180)

Genome-wide assessment of differential effector gene use in embryogenesis [PDF]

, 2015
Six different populations of cells were isolated by FACS from disaggregated late blastula and gastrula stage sea urchin embryos according to the regulatory states expressed in these cells, as reported by recombineered BACs producing fluorochromes ...
Barsi, Julius C., Calestani, Cristina, Davidson, Eric H., Tu, Qiang   +3 more
core   +2 more sources

Multidimensional Engineering of Escherichia coli for Efficient Adipic Acid Synthesis From Cyclohexane

Advanced Science, Volume 12, Issue 14, April 10, 2025.
An engineered Escherichia coli is developed to efficiently produce adipic acid (AA) from cyclohexanol, KA oil (a mixture of cyclohexanol and cyclohexanone), or cyclohexane through a combination of enzyme screening, protein fusion, and genome editing techniques. This approach has achieved the highest recorded productivity for biological AA production to
Fei Wang, Huiqi Sun, Di Deng, Yuanqing Wu, Jing Zhao, Qian Li, Aitao Li   +6 more
wiley   +1 more source

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids [PDF]

, 2018
Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks change to control novel developmental phenotypes remains, in most cases, unresolved. Here, we address GRN evolution by comparing the
Davidson, Eric H., Erkenbrack, Eric M., Peter, Isabelle S.   +2 more
core   +1 more source

Tracheal development in the Drosophila brain is constrained by glial cells [PDF]

, 2007
The Drosophila brain is tracheated by the cerebral trachea, a branch of the first segmental trachea of the embryo. During larval stages the cerebral trachea splits into several main (primary) branches that grow around the neuropile, forming a ...
Cruz, Luis, Hartenstein, Volker, Pereanu, Wayne, Spindler, Shana   +3 more
core   +1 more source

PlantTFDB 4.0: toward a central hub for transcription factors and regulatory interactions in plants

Nucleic Acids Res., 2016
With the goal of providing a comprehensive, high-quality resource for both plant transcription factors (TFs) and their regulatory interactions with target genes, we upgraded plant TF database PlantTFDB to version 4.0 (http://planttfdb.cbi.pku.edu.cn ...
Jinpu Jin, Feng Tian, Dechang Yang, Yuqi Meng, Lei Kong, Jingchu Luo, Ge Gao   +6 more
semanticscholar   +1 more source

Building developmental gene regulatory networks [PDF]

, 2009
Animal development is an elaborate process programmed by genomic regulatory instructions. Regulatory genes encode transcription factors and signal molecules, and their expression is under the control of cis-regulatory modules that define the logic of ...
Davidson, Eric H., Li, Enhu
core   +1 more source

Specific functions of the Wnt signaling system in gene regulatory networks throughout the early sea urchin embryo [PDF]

, 2014
Wnt signaling affects cell-fate specification processes throughout embryonic development. Here we take advantage of the well-studied gene regulatory networks (GRNs) that control pregastrular sea urchin embryogenesis to reveal the gene regulatory ...
Cui, Miao, Davidson, Eric H., Li, Enhu, Peter, Isabelle S., Siriwon, Natnaree   +4 more
core   +2 more sources

Early asymmetric cues triggering the Dorsal/Ventral Gene Regulatory Network of the sea urchin embryo [PDF]

, 2014
Dorsal/ventral (DV) patterning of the sea urchin embryo relies on a ventrally-localized organizer expressing Nodal, a pivotal regulator of the DV gene regulatory network.
Agca, Angerer, Angerer, Ben-Tabou de-Leon, Bergeron, Bessodes, Bolouri, Bradham, Bradham, Brandhorst, Cameron, Cavalieri, Cavalieri, Cavalieri, Cavalieri, Cavalieri, Cavalieri, Cavalieri, Chen, Child, Coffman, Coffman, Coffman, Coffman, Czihak, De Robertis, Di Bernardo, Di Bernardo, Driesch, Duboc, Duboc, Duboc, Flowers, Flytzanis, Franks, Hoey, Horstadius, Houde, Hough-Evans, Hurley, Kitamura, Lapraz, Li, Li, Materna, Materna, Molina, Nam, Oliveri, Oliveri, Oliveri, Pease, Range, Range, Ransick, Revilla-i-Domingo, Röttinger, Saudemont, Smith, Su, Svingen, Wang, Yaguchi, Yaguchi, Yaguchi, Yamazaki, Zhou   +66 more
core   +3 more sources

Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I. [PDF]

, 2013
Verrucosidin (VCD) belongs to a group of fungal metabolites that were identified in screening programs to detect molecules that preferentially kill cancer cells under glucose-deprived conditions.
Chen, Thomas C, Gonzalez, Reyna, Hofman, Florence M, Louie, Stan G, Pao, Peng-Wen, Pirrung, Michael C, Schönthal, Axel H, Sharma, Natasha, Thomas, Simmy   +8 more
core   +2 more sources

Deciphering the dynamic code: DNA recognition by transcription factors in the ever-changing genome

Transcription
Transcription factors (TFs) intricately navigate the vast genomic landscape to locate and bind specific DNA sequences for the regulation of gene expression programs.
Yumi Minyi Yao, Irina Miodownik, Michael P O'Hagan, Muhammad Jbara, Ariel Afek   +4 more
semanticscholar   +1 more source