Ring-Opening Polymerization of ε-Caprolactone Initiated by Ganciclovir (GCV) for the Preparation of GCV-Tagged Polymeric Micelles [PDF]
Ganciclovir (GCV) is a nucleoside analogue with antiviral activity against herpes viral infections, and the most widely used antiviral to treat cytomegalovirus infections.
Alicia J. Sawdon, C. Peng
semanticscholar +5 more sources
A GCV based Arnoldi-Tikhonov regularization method [PDF]
For the solution of linear discrete ill-posed problems, in this paper we consider the Arnoldi-Tikhonov method coupled with the Generalized Cross Validation for the computation of the regularization parameter at each iteration.
Novati, Paolo, Russo, Maria Rosaria
core +5 more sources
Gene Therapy with HSV1-sr39TK/GCV Exhibits a Stronger Therapeutic Efficacy Than HSV1-TK/GCV in Rat C6 Glioma Cells [PDF]
Although the combination of herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) with ganciclovir (GCV) has been shown as a promising suicide gene treatment strategy for glioma, the almost immunodepressive dose of GCV required for its adequate in ...
Lei-qing Li +5 more
semanticscholar +4 more sources
Hepatoma-Targeted Radionuclide Immune Albumin Nanospheres: 131I-antiAFPMcAb-GCV-BSA-NPs [PDF]
An effective strategy has been developed for synthesis of radionuclide immune albumin nanospheres (131I-antiAFPMcAb-GCV-BSA-NPs). In vitro as well as in vivo targeting of 131I-antiAFPMcAb-GCV-BSA-NPs to AFP-positive hepatoma was examined.
Mei Lin +8 more
semanticscholar +4 more sources
Practical use of robust GCV and modified GCV for spline smoothing [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
M. A. Lukas, F. Hoog, R. Anderssen
semanticscholar +2 more sources
Generalized Cross Validation (GCV) in Smoothing Spline Nonparametric Regression Models
A nonparametric regression model is utilized if the the regression curve does not contain information about the accepted shape and accepted curve is exist in a function.
M. Maharani, D. R. S. Saputro
semanticscholar +2 more sources
Performance of Robust GCV and Modified GCV for Spline Smoothing [PDF]
Abstract. While it is a popular selection criterion for spline smoothing, generalized cross‐validation (GCV) occasionally yields severely undersmoothed estimates. Two extensions of GCV called robust GCV (RGCV) and modified GCV have been proposed as more stable criteria. Each involves a parameter that must be chosen, but the only guidance has come from
M. A. Lukas, F. D. de Hoog, R. Anderssen
semanticscholar +3 more sources
GCV for Tikhonov regularization via global Golub–Kahan decomposition
SummaryGeneralized cross validation is a popular approach to determining the regularization parameter in Tikhonov regularization. The regularization parameter is chosen by minimizing an expression, which is easy to evaluate for small‐scale problems, but prohibitively expensive to compute for large‐scale ones.
C. Fenu, L. Reichel, G. Rodriguez
semanticscholar +5 more sources
GCVS problems with flare stars [PDF]
The astrometric aspect of cataloguing variable stars becomes more and more important. During the past thirty years there has been approximately an three-fold increase of the number of known variables; now the rate of new discoveries becomes extremely high, and we may expect a new twofold increase in a couple of years due to discoveries made with space ...
Elena V. Kazarovets, Nikolai N. Samus
openaire +1 more source
Hybrid and Iteratively Reweighted Regularization by Unbiased Predictive Risk and Weighted GCV for Projected Systems [PDF]
Tikhonov regularization for projected solutions of large-scale ill-posed problems is considered. The Golub-Kahan iterative bidiagonalization is used to project the problem onto a subspace and regularization then applied to find a subspace approximation ...
R. Renaut, S. Vatankhah, V. E. Ardestani
semanticscholar +1 more source

