Results 61 to 70 of about 444,530 (310)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Analysis of the effects of BrdU on DLKP human lung cancer cells by two-dimensional difference gel electrophoresis and mass spectrometry [PDF]
, 2007 Bromodeoxyuridine (BrdU) is a thymidiie analogue that incorporates into DNA of dividing cells during the S-phase of the cell cycle. Previous work in laboratories reported that treatment with lOyM BrdU in the human lung carcinoma cell line (DLKP) resulted
Henry, Michael
core
Screening, Enrichment and Structural Identification of Bitter Almond Antibacterial Peptides
Shipin gongye ke-jiTo explore the preparation, enrichment, and structural analysis of bitter almond antimicrobial peptides, in this experiment, the protein was extracted from the defatted bitter almonds, and the protein was hydrolyzed by enzymes to prepare bitter almond ...
Tao ZHANG +5 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Molecular Weight Characterisation of Pinus radiata Bark Condensed Tannins [PDF]
, 2007 Crude condensed tannins extracted from Pinus radiata bark (sourced from Tokoroa) with various solvents (Hot water (HW), methanol/water/acetic acid (MWA), acetone/water (AW) and hot aqueous 2% sulphite/urea solution (SFU)) were subjected to Sephadex LH-20
Bogun, Ben Rowan
core
Identification of bile alcohols in urine from healthy humans.
Journal of Lipid Research, 1984 Bile alcohols present in urine from healthy adults were studied. Urine was extracted with octadecylsilane-bonded silica gel, and a neutral fraction and a glucuronide fraction were isolated by ion exchange chromatography on piperidinohydroxypropyl ...
M Kuwabara +4 more
doaj +1 more source
Studies on the chemical compositions of Hyptis suaveolens (L.) Poit [PDF]
Journal of the Serbian Chemical Society, 2019 This study aimed at identifying the chemical compounds isolated from the aerial parts and roots of Hyptis suaveolens (L.) Poit. The compounds were isolated and purified by a combination of various chromatographic techniques including silica gel column ...
Tang Gengqiu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Desenvolvimento e aplicação de fases extratoras para técnicas de preparação de amostras [PDF]
, 2009 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Químca.A fragilidade da sílica fundida e a necessidade de suportes robustos para microextração em fase sólida (SPME) têm ...
Budziak, Dilma
core
Purification of the Rv0045c protein by ion exchange chromatography and gel filtration chromatography. [PDF]
, 2013 The Rv0045c protein was purified by anion exchange chromatography (A), cation exchange chromatography (B), and gel filtration chromatography (C). The purity was checked by SDS-PAGE analysis after each purification procedure.
Kehui Xu (361209) +8 more
core +1 more source